(Q35882448)

10 August 2017

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title

Isoprenoids: remarkable diversity of form and function (English)

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10 August 2017

Sarah A Holstein

1

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10 August 2017

Raymond J Hohl

series ordinal

2

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10 August 2017

publication date

1 April 2004

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10 August 2017

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10 August 2017

volume

39

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10 August 2017

issue

4

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10 August 2017

page(s)

293-309

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Regulatory adaptation of isoprenoid biosynthesis and the LDL receptor pathway in fibroblasts from patients with mevalonate kinase deficiency

10 August 2017

cites work

1 reference

12 December 2020

Trans-beta-farnesene as a feeding stimulant for the sand fly Lutzomyia longipalpis (Diptera: Psychodidae).

1 reference

12 December 2020

Prokaryotic hopanoids: the biosynthesis of the bacteriohopane skeleton. Formation of isoprenic units from two distinct acetate pools and a novel type of carbon/carbon linkage between a triterpene and D-ribose

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12 December 2020

Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes.

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12 December 2020

Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level.

1 reference

12 December 2020

Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii

1 reference

12 December 2020

Stimulation of prostaglandin production by (2E,6Z,10E)-7-hydroxymethyl-3,11,15-trimethyl-2,6,10,14-++ +hexadecatetrae n-1-ol (plaunotol), a new anti-ulcer drug, in vitro and in vivo

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12 December 2020

Studies on mevinolin production by some fungi

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12 December 2020

Control of Rab5 and Rab7 expression by the isoprenoid pathway

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12 December 2020

Structure-activity relationships of seco-prezizaane terpenoids in gamma-aminobutyric acid receptors of houseflies and rats

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12 December 2020

Astroglial activation accompanies heat shock protein upregulation in rat brain following single oral dose of geranylgeranylacetone

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12 December 2020

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium

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12 December 2020

A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

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12 December 2020

Endothelium-dependent effects of statins

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12 December 2020

Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: isopentenyl monophosphate kinase catalyzes the terminal enzymatic step

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12 December 2020

Differential effects of monoterpenes and lovastatin on RAS processing

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12 December 2020

Therapeutic effects of ML-236B in primary hypercholesterolemia

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12 December 2020

Dihydroheptaprenyl and dihydrodecaprenyl monophosphates induce apoptosis mediated by activation of caspase-3-like protease.

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12 December 2020

Aerobic biodegradation of selected monoterpenes.

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12 December 2020

Specific inhibition of desmosterol synthesis by ML--236B in mouse LM cells grown in suspension in a lipid-free medium

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12 December 2020

Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.

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12 December 2020

Human liver alcohol dehydrogenases catalyze the oxidation of the intermediary alcohols of the shunt pathway of mevalonate metabolism

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12 December 2020

Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase

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12 December 2020

Biosynthesis of the labdane diterpene marrubiin in Marrubium vulgare via a non-mevalonate pathway

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12 December 2020

Metabolism of farnesol: phosphorylation of farnesol by rat liver microsomal and peroxisomal fractions

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12 December 2020

New terpene hydrocarbons from the alligatoridae (crocodylia, reptilia).

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12 December 2020

A new dehydrogeranylgeraniol antioxidant from Saururus cernuus that inhibits intracellular reactive oxygen species (ROS)-catalyzed oxidation within HL-60 cells.

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12 December 2020

Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.

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12 December 2020

PURIFICATION OF GERANYLGERANYL PYROPHOSPHATE SYNTHETASE FROM MICROCOCCUS LYSODEIKTICUS

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12 December 2020

Alcanivorax which prevails in oil-contaminated seawater exhibits broad substrate specificity for alkane degradation

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12 December 2020

Mevalonic aciduria: an inborn error of cholesterol biosynthesis?

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12 December 2020

Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

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12 December 2020

Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol.

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12 December 2020

Identification of a nuclear receptor for bile acids

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12 December 2020

Identification of a nuclear receptor that is activated by farnesol metabolites

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12 December 2020

Pleurotus fungi produce mevinolin, an inhibitor of HMG CoA reductase

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12 December 2020

Gas chromatographic separation of diastereomeric isoprenoids as molecular markers of oil pollution

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12 December 2020

Incorporation of radioactivity into amino acids and fatty acids after administration of 14C-geranylgeranylacetone to rats

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12 December 2020

Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis

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12 December 2020

Geranylgeranylacetone suppresses spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric pit cells

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12 December 2020

Evidence for farnesol-mediated isoprenoid synthesis regulation in a halophilic archaeon, Haloferax volcanii

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12 December 2020

Acyclo-retinoic acid induces apoptosis in human prostate cancer cells

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12 December 2020

Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A

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12 December 2020

Genetic distinction between sterol-mediated transcriptional and posttranscriptional control of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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12 December 2020

Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some gram-negative bacteria and mycobacteria

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12 December 2020

Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells

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12 December 2020

Isoprenoid Pyrophosphate Analogues Regulate Expression of Ras-Related Proteins

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12 December 2020

Phase I and pharmacokinetic study of D-limonene in patients with advanced cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee

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12 December 2020

Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase

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12 December 2020

Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites.

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12 December 2020

Induction of heat shock protein-70 (hsp-70) by intraarterial administration of geranylgeranylacetone

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12 December 2020

Lovastatin biosynthesis by Aspergillus terreus in a chemically defined medium

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12 December 2020

Statins as cellular antithrombotics

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12 December 2020

[On the biosynthesis of terpenes. XIV. On the determination of phosphomevalonic acid kinase and pyrophosphomevalonic acid decarboxylase in cell extracts]

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12 December 2020

Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome

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12 December 2020

Mechanism of aminobisphosphonate action: characterization of alendronate inhibition of the isoprenoid pathway

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12 December 2020

Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol

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12 December 2020

Polyprenyl diphosphate synthases

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12 December 2020

Suppression of Helicobacter pylori-induced interleukin-8 production in gastric cancer cell lines by an anti-ulcer drug, geranylgeranylacetone

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12 December 2020

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

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12 December 2020

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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12 December 2020

Mevinolin: a highly specific inhibitor of microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase of radish plants

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12 December 2020

Identification of an active site alanine in mevalonate kinase through characterization of a novel mutation in mevalonate kinase deficiency

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12 December 2020

Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum

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12 December 2020

Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines

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12 December 2020

Antiulcer effect of geranylgeranylacetone, a new acyclic polyisoprenoid on experimentally induced gastric and duodenal ulcers in rats

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12 December 2020

Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.

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12 December 2020

Characterization of two distinct allyl pyrophosphatase activities from rat liver microsomes

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12 December 2020

Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation

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12 December 2020

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

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12 December 2020

Determination of isopentenyl diphosphate and farnesyl diphosphate in tissue samples with a comment on secondary regulation of polyisoprenoid biosynthesis

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12 December 2020

Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation

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12 December 2020

A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days

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12 December 2020

Effect of plaunotol on superoxide production activity in vivo

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12 December 2020

Temperature dependence of mutant mevalonate kinase activity as a pathogenic factor in hyper-IgD and periodic fever syndrome

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12 December 2020

Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate

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12 December 2020

Prevention and therapy of cancer by dietary monoterpenes

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12 December 2020

THE BIOSYNTHESIS OF MEVALONIC ACID.

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12 December 2020

Cholesterol biosynthesis in preparations of liver from normal, fasting, x-irradiated, cholesterol-fed, triton, or delta 4-cholesten-3-one-treated rats.

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12 December 2020

Some nutritional factors influencing mevinolin production by Aspergillus terreus strain

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12 December 2020

Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta

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12 December 2020

5′-AMP is a direct precursor of cytokinin in Dictyostelium discoideum

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12 December 2020

Purification and characterization of an autoregulatory substance capable of regulating the morphological transition in Candida albicans

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12 December 2020

Blood glucose- and triglyceride-lowering effect of trans-dehydrocrotonin, a diterpene from Croton cajucara Benth., in rats

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12 December 2020

Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum

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12 December 2020

Microbial degradation of monoterpenes in the absence of molecular oxygen.

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12 December 2020

Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras.

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12 December 2020

Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus

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12 December 2020

Kinetic Analysis of the Reaction Catalyzed by Rat-Liver 3-Hydroxy-3-methylglutaryl-coenzyme-A Reductase Using Two Specific Inhibitors

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12 December 2020

Effects of HMG-CoA reductase inhibitors on coagulation and fibrinolysis processes

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12 December 2020

Cloning and nucleotide sequence of the ispA gene responsible for farnesyl diphosphate synthase activity in Escherichia coli

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12 December 2020

Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast

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12 December 2020

Preferential induction of apoptosis of leukaemic cells by farnesol

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12 December 2020

Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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12 December 2020

Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.

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12 December 2020

Hyperimmunoglobulinaemia D and periodic fever: a new syndrome

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12 December 2020

Geranylgeranylacetone, a novel anti-ulcer drug, stimulates mucus synthesis and secretion in rat gastric cultured cells

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12 December 2020

Conjugated triene oxidation products of alpha-farnesene induce symptoms of superficial scald on stored apples

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12 December 2020

Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients

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12 December 2020

Metabolism of [3H]farnesol to cholesterol and cholesterogenic intermediates in the living rat eye

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12 December 2020

Antibodies to N6-(delta2-isopentenyl) adenosine and its nucleotide: interaction with purified tRNAs and with bases, nucleosides and nucleotides of the isopentenyladenosine family

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12 December 2020

In vitro antileishmanial effects of antibacterial diterpenes from two Ethiopian Premna species: P. schimperi and P. oligotricha

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12 December 2020

Inhibition of the transcription factor NF-kappa B by sesquiterpene lactones from Podachaenium eminens

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12 December 2020

Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.

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12 December 2020

Purification of a mammalian protein geranylgeranyltransferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex

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12 December 2020

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12 December 2020

Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes

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12 December 2020

Evaluation of morphogenic regulatory activity of farnesoic acid and its derivatives against Candida albicans dimorphism

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12 December 2020

Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate synthase from Capsicum annuum: correlative increase in enzyme activity and transcript level during fruit ripening

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12 December 2020

Geranyl pyrophosphate synthase: characterization of the enzyme and evidence that this chain-length specific prenyltransferase is associated with monoterpene biosynthesis in sage (Salvia officinalis)

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12 December 2020

Enzymic synthesis of juvenile hormone in locust corpora allata: evidence for a microsomal cytochrome P-450 linked methyl farnesoate epoxidase

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12 December 2020

Early use of statins in acute coronary syndromes

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12 December 2020

Biodegradation of free phytol by bacterial communities isolated from marine sediments under aerobic and denitrifying conditions.

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12 December 2020

Formation of (R)-2,3-dihydrogeranylgeranoic acid from geranylgeraniol in rat thymocytes

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12 December 2020

Identification and characterization of three novel missense mutations in mevalonate kinase cDNA causing mevalonic aciduria, a disorder of isoprene biosynthesis

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12 December 2020

Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

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12 December 2020

Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase

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12 December 2020

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

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12 December 2020

Substrate specificity for the epoxidation of terpenoids and active site topology of house fly cytochrome P450 6A1.

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12 December 2020

Male jeffrey pine beetle, Dendroctonus jeffreyi, synthesizes the pheromone component frontalin in anterior midgut tissue

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12 December 2020

Mevalonic aciduria: pathobiochemical effects of mevalonate kinase deficiency on cholesterol metabolism in intact fibroblasts

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12 December 2020

The mechanism of geranylgeraniol-induced apoptosis involves activation, by a caspase-3-like protease, of a c-jun N-terminal kinase signaling cascade and differs from mechanisms of apoptosis induced by conventional chemotherapeutic drugs

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12 December 2020

The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms

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12 December 2020

Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy

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12 December 2020

Biodegradation of cis-1,4-polyisoprene rubbers by distinct actinomycetes: microbial strategies and detailed surface analysis.

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12 December 2020

Phosphorylation of geranyl and farnesyl pyrophosphates by Nm23 proteins/nucleoside diphosphate kinases

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12 December 2020

Inhibitory effects on lipid metabolism in cultured cells of ML-236B, a potent inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase

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12 December 2020

Effects of geranylgeranoic acid in bone: induction of osteoblast differentiation and inhibition of osteoclast formation

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12 December 2020

Insect antifeedant activity of clerodane diterpenes and related model compounds

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12 December 2020

Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection

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12 December 2020

Polyketide biosynthesis: a millennium review

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12 December 2020

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

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12 December 2020

Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol

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12 December 2020

Plaunotol prevents indomethacin-induced gastric mucosal injury in rats by inhibiting neutrophil activation

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12 December 2020

Isoprenoid enzyme systems of silkworm. II. Formation of the juvenile hormone skeletons by farnesyl pyrophosphate synthetase II.

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12 December 2020

Bile acids: natural ligands for an orphan nuclear receptor

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12 December 2020

Antifungal diterpenes from Hypoestes serpens (Acanthaceae).

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12 December 2020

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates

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12 December 2020

Creating isoprenoid diversity

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12 December 2020

A hydroxymethylglutaryl-CoA reductase inhibitor synthesized by yeasts

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12 December 2020

Anti-inflammatory and immunomodulatory effects of statins.

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12 December 2020

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

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12 December 2020

Structure and juvenile hormone-mediated regulation of the HMG-CoA reductase gene from the Jeffrey pine beetle, Dendroctonus jeffreyi

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12 December 2020

Farnesol-induced generation of reactive oxygen species via indirect inhibition of the mitochondrial electron transport chain in the yeast Saccharomyces cerevisiae.

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12 December 2020

Regulation of HMG-CoA reductase activity in plants.

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12 December 2020

Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro

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12 December 2020

Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells

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12 December 2020

Mevalonic kinase: purification and properties.

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12 December 2020

Inhibition of squalene synthase and squalene epoxidase in tobacco cells triggers an up-regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase

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12 December 2020

Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells

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12 December 2020

A cytochrome P450 terpenoid hydroxylase linked to the suppression of insect juvenile hormone synthesis

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12 December 2020

Farnesol biosynthesis in Candida albicans: cellular response to sterol inhibition by zaragozic acid B.

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12 December 2020

Identification and characterization of geranylgeraniol kinase and geranylgeranyl phosphate kinase from the Archaebacterium Sulfolobus acidocaldarius.

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12 December 2020

Aerobic and anaerobic metabolism of squalene by a denitrifying bacterium isolated from marine sediment

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12 December 2020

Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene

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12 December 2020

Hypolipidemic effects in monkeys of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase

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12 December 2020

Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart

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12 December 2020

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

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12 December 2020

Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death

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12 December 2020

Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases.

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12 December 2020

Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials.

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12 December 2020

Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease

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12 December 2020

Prokaryotic triterpenoids. A novel hopanoid from the ethanol-producing bacterium Zymomonas mobilis

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12 December 2020

Intensive statin therapy--a sea change in cardiovascular prevention

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12 December 2020

Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats

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12 December 2020

Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha

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12 December 2020

Long-chain betulaprenol-type polyprenols from the leaves of Ginkgo biloba

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12 December 2020

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

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12 December 2020

Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes

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12 December 2020

Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents

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12 December 2020

3-Hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured fibroblasts from patients with mevalonate kinase deficiency: differential response to lipid supplied by fetal bovine serum in tissue culture medium

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12 December 2020

Activation of mammalian retinoid X receptors by the insect growth regulator methoprene

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12 December 2020

Strategies for transgenic manipulation of monoterpene biosynthesis in plants

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12 December 2020

Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene

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12 December 2020

Phase I study of perillyl alcohol in patients with refractory malignancies

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12 December 2020

Statins have biphasic effects on angiogenesis

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12 December 2020

African elephant sesquiterpenes

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12 December 2020

Farnesyl analogues inhibit vasoconstriction in animal and human arteries

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12 December 2020

Geranylgeraniol, an intermediate product in mevalonate pathway, induces apoptotic cell death in human hepatoma cells: death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression

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12 December 2020

Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol

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12 December 2020

Selective farnesol toxicity and translocation of protein kinase C in neoplastic HeLa-S3K and non-neoplastic CF-3 cells

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12 December 2020

Clinical and biochemical phenotype in 11 patients with mevalonic aciduria.

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12 December 2020

Non-sterol compounds that regulate cholesterogenesis. Analogues of farnesyl pyrophosphate reduce 3-hydroxy-3-methylglutaryl-coenzyme A reductase levels.

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12 December 2020

Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model

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12 December 2020

Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome

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12 December 2020

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

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12 December 2020

Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase

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12 December 2020

A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway

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12 December 2020

Modulation of neuronal voltage-gated calcium channels by farnesol.

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12 December 2020

Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule

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12 December 2020

Regression of rat primary mammary tumors following dietary d-limonene

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12 December 2020

Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day

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12 December 2020

Squalene synthetase. 3. Mechanism of the reaction

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12 December 2020

Phase I clinical trial of perillyl alcohol administered daily.

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12 December 2020

Farnesol Inhibits L-type Ca2+Channels in Vascular Smooth Muscle Cells

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12 December 2020

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates

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12 December 2020

Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii.

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12 December 2020

Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 24(S),25-oxidolanosterol

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12 December 2020

Rapid loss in the mitochondrial membrane potential during geranylgeranoic acid-induced apoptosis

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12 December 2020

Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia

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12 December 2020

Clinical and molecular variability in childhood periodic fever with hyperimmunoglobulinaemia D.

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12 December 2020

In-vitro and in-vivo antibacterial activity of plaunotol, a cytoprotective antiulcer agent, against Helicobacter pylori

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12 December 2020

Interactions of plaunotol with bacterial membranes.

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12 December 2020

Inhibition of isoprenoid biosynthesis and the post-translational modification of pro-p21.

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12 December 2020

Isolation and characterization of a prenylcysteine lyase from bovine brain

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12 December 2020

Chemistry of male dominance in the house mouse, Mus domesticus

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12 December 2020

Isoprenyl diphosphate synthases

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12 December 2020

Hydrocarbon Metabolism by Brevibacterium erythrogenes : Normal and Branched Alkanes

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12 December 2020

Identification of a mutation cluster in mevalonate kinase deficiency, including a new mutation in a patient of Mennonite ancestry.

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12 December 2020

Geranylgeraniol is a potent inducer of apoptosis in tumor cells

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12 December 2020

Interspecific variation in terpenoid composition of defensive secretions of European Reticulitermes termites

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12 December 2020

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

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12 December 2020

Sex attractant pheromone of the red-shouldered stink bug Thyanta pallidovirens: a pheromone blend with multiple redundant components.

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12 December 2020

Anaerobic mineralization of cholesterol by a novel type of denitrifying bacterium

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12 December 2020

Anti-tumor promoting diterpenes from the stem bark of Thuja standishii (Cupressaceae).

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12 December 2020

On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts.

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12 December 2020

Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity

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12 December 2020

Geranylgeranylacetone, a heat shock protein inducer, prevents primary graft nonfunction in rat liver transplantation

1 reference

12 December 2020

The statins as anticancer agents

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12 December 2020

Variable product specificity of microsomal dehydrodolichyl diphosphate synthase from rat liver.

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12 December 2020

Biochemistry and molecular biology of de novo isoprenoid pheromone production in the Scolytidae

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12 December 2020

cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase

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12 December 2020

Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

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12 December 2020

Mammalian protein geranylgeranyltransferase. Subunit composition and metal requirements

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12 December 2020

Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway

1 reference

12 December 2020

Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells

1 reference

12 December 2020

Monoterpene regulation of Ras and Ras-related protein expression

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12 December 2020

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents

1 reference

12 December 2020

Geranylgeraniol causes a decrease in levels of calreticulin and tyrosine phosphorylation of a 36-kDa protein prior to the appearance of apoptotic features in HL-60 cells

1 reference

12 December 2020

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

12 December 2020

Growth inhibition of yeast by compactin (ML-236B) analogues

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12 December 2020

Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors

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12 December 2020

Control of RAS mRNA level by the mevalonate pathway

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12 December 2020

Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver

1 reference

12 December 2020

Isoprenoids influence expression of Ras and Ras-related proteins

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12 December 2020

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

1 reference

12 December 2020

Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells

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12 December 2020

Perillyl alcohol, an inhibitor of geranylgeranyl transferase, induces apoptosis of immortalized human vascular smooth muscle cells in vitro

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12 December 2020

Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa

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12 December 2020

Feedback Control of Mevalonate Synthesis by Dietary Cholesterol

1 reference

12 December 2020

Distinct sterol and nonsterol signals for the regulated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

12 December 2020

Identification of urinary and microsomal metabolites of geranylgeranylacetone in rats

1 reference

12 December 2020

Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions

1 reference

12 December 2020

Decreased plasma ubiquinone-10 concentration in patients with mevalonate kinase deficiency

1 reference

12 December 2020

Daucane phytoestrogens: a structure-activity study

1 reference

12 December 2020

Metabolism of mevalonic acid in cell-free homogenates of bovine retinas. Formation of novel isoprenoid acids

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12 December 2020

Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis

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12 December 2020

2-Methylhopanoids as biomarkers for cyanobacterial oxygenic photosynthesis

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12 December 2020

The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways.

1 reference

12 December 2020

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1 reference

12 December 2020

Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro

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12 December 2020

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.32.852

Identifiers

DOI

10.1007/S11745-004-1233-3

1 reference

10 August 2017

1 reference