(Q35892821)

English

Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disorders

scientific article published on 17 February 2012

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disorders (English)

1 reference

Europe PubMed Central

11 August 2017

neurodevelopmental disorder

1 reference

based on heuristic

inferred from title

Robert O Wright

4

object named as

Robert O Wright

1 reference

Europe PubMed Central

11 August 2017

author name string

Kirstie H Stansfield

1

1 reference

Europe PubMed Central

11 August 2017

J Richard Pilsner

2

1 reference

Europe PubMed Central

11 August 2017

Quan Lu

3

1 reference

Europe PubMed Central

11 August 2017

Tomás R Guilarte

5

1 reference

Europe PubMed Central

11 August 2017

publication date

17 February 2012

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Europe PubMed Central

11 August 2017

Toxicological Sciences

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Europe PubMed Central

11 August 2017

127

1 reference

Europe PubMed Central

11 August 2017

1

1 reference

Europe PubMed Central

11 August 2017

277-295

1 reference

Europe PubMed Central

11 August 2017

Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's disease

1 reference

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The continuing impact of lead dust on children's blood lead: comparison of public and private properties in New Orleans

1 reference

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BDNF-TrkB signalling in fear learning: from genetics to neural networks

1 reference

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Molecular neurobiology of lead (Pb(2+)): effects on synaptic function

1 reference

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Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.

1 reference

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Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling

1 reference

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Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival.

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Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.

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Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.

1 reference

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Blood lead concentrations < 10 microg/dL and child intelligence at 6 years of age.

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MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production

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BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae.

1 reference

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The relationship between early childhood blood lead levels and performance on end-of-grade tests

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Fetal lead exposure at each stage of pregnancy as a predictor of infant mental development

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Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

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The ups and downs of BDNF in Rett syndrome

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Blood lead levels in children after phase-out of leaded gasoline in Bombay, India

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Low-level environmental lead exposure and children's intellectual function: an international pooled analysis

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The excitoprotective effect of N-methyl-D-aspartate receptors is mediated by a brain-derived neurotrophic factor autocrine loop in cultured hippocampal neurons

1 reference

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Calcium/calmodulin-dependent protein kinase II activity and expression are altered in the hippocampus of Pb2+- exposed rats

1 reference

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Neurotrophin-mediated rapid signaling in the central nervous system: mechanisms and functions

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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

1 reference

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The synaptic vesicle cycle

1 reference

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Prenatal lead exposure, delta-aminolevulinic acid, and schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

1 reference

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11 July 2018

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Neurotrophin secretion: current facts and future prospects

1 reference

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11 July 2018

Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Trk receptors: roles in neuronal signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Environmental enrichment reverses cognitive and molecular deficits induced by developmental lead exposure

1 reference

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11 July 2018

Mechanism of TrkB-mediated hippocampal long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Brain-derived neurotrophic factor-induced potentiation of Ca(2+) oscillations in developing cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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Regulation of cell survival by secreted proneurotrophins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

N-methyl-D-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

11 July 2018

CoREST: a functional corepressor required for regulation of neural-specific gene expression

1 reference

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11 July 2018

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327871

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Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

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1 reference

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Retrograde signaling in the development and modification of synapses

2 references

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11 July 2018

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Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons.

1 reference

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11 July 2018

Neurotrophins live or let die: does p75NTR decide?

1 reference

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1 reference

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1 reference

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Transphosphorylation of the neurotrophin Trk receptors

1 reference

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1 reference

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Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation

1 reference

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The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins

1 reference

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Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead.

1 reference

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1 reference

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1 reference

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Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons

1 reference

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1 reference

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

1 reference

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24 September 2018

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

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24 September 2018

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1 reference

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24 September 2018

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24 September 2018

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24 September 2018

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1 reference

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24 September 2018

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1 reference

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24 September 2018

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24 September 2018

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12 December 2020

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Lead poisoning among Arab American and African American children in the Detroit metropolitan area, Michigan

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https://pubmed.ncbi.nlm.nih.gov/22345308

12 December 2020

based on heuristic

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Neonatal lead exposure alters the dendritic development of hippocampal dentate granule cells

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https://pubmed.ncbi.nlm.nih.gov/22345308

12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/22345308

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Synapsins as mediators of BDNF-enhanced neurotransmitter release

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https://pubmed.ncbi.nlm.nih.gov/22345308

12 December 2020

based on heuristic

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Identifiers

10.1093/TOXSCI/KFS090

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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