(Q35895616)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

Zachary Charlop-Powers

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

5

Sean F Brady

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

author name string

Daniel Montiel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Hahk-Soo Kang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Fang-Yuan Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

language of work or name

English

0 references

publication date

6 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

18 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

issue

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

page(s)

8953-8958

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors

18 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Mutations in the proteolipid subunits of the vacuolar H+-ATPase provide resistance to indolotryptoline natural products

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

A roadmap for natural product discovery based on large-scale genomics and metabolomics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Expression of codon optimized genes in microbial systems: current industrial applications and perspectives.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Challenges and triumphs to genomics-based natural product discovery

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Reassembly of functionally intact environmental DNA-derived biosynthetic gene clusters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Interfering with pH regulation in tumours as a therapeutic strategy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Cloning and characterization of an environmental DNA-derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Genomic basis for natural product biosynthetic diversity in the actinomycetes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Function, structure and regulation of the vacuolar (H+)-ATPases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Yeast DNA ligase IV mediates non-homologous DNA end joining

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Micro-homology mediated PCR targeting in Saccharomyces cerevisiae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Essential structure ofE. colipromoter effect of spacer length between the two consensus sequences on promoter function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Compilation and analysis of DNA sequences associated with apparent streptomycete promoters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Reconstruction of cladoniamide biosynthesis reveals nonenzymatic routes to bisindole diversity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Synthesis and assignment of the absolute configuration of indenotryptoline bisindole alkaloid BE-54017.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

The construction of a library of synthetic promoters revealed some specific features of strong Streptomyces promoters.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

V-ATPase inhibitors and implication in cancer treatment.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Divergent pathways in the biosynthesis of bisindole natural products

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4517240

Synthetic Biology in Streptomyces Bacteria

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1507606112

Triggering cryptic natural product biosynthesis in microorganisms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26150486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mining microbial genomes for new natural products and biosynthetic pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26150486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cladoniamides A−G, Tryptophan-Derived Alkaloids Produced in Culture byStreptomyces uncialis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26150486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1507606112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26150486%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference