(Q43975942)

28 November 2017

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives (English)

1 reference

28 November 2017

Alfredo F Braña

3

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Carmen Méndez

object named as

Carmen Méndez

5

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author name string

César Sánchez

1

1 reference

28 November 2017

Igor A Butovich

2

1 reference

28 November 2017

Jürgen Rohr

4

1 reference

28 November 2017

José A Salas

6

1 reference

28 November 2017

1 April 2002

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28 November 2017

Chemistry and Biology

1 reference

28 November 2017

9

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28 November 2017

4

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28 November 2017

519-531

1 reference

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

28 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Isolation and structure of rebeccamycin - a new antitumor antibiotic from nocardia aerocoligenes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Production and biological activity of rebeccamycin, a novel antitumor agent.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Recent developments of rebeccamycin analogues as topoisomerase I inhibitors and antitumor agents

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Microbial biosynthesis of halometabolites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Cloning and expression of a gene encoding N-glycosyltransferase (ngt) from Saccarothrix aerocolonigenes ATCC39243.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A new shuttle cosmid vector, pKC505, for streptomycetes: its use in the cloning of three different spiramycin-resistance genes from a Streptomyces ambofaciens library

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Antimicrobial activities of indolocarbazole and bis-indole protein kinase C inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

The biosynthetic origins of rebeccamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Biosynthesis of staurosporine, 2. Incorporation of tryptophan

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Identification of indolepyruvic acid as an intermediate of rebeccamycin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Purification and cloning of an apoptosis-inducing protein derived from fish infected with Anisakis simplex, a causative nematode of human anisakiasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Complete genome sequence of Caulobacter crescentus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Production, isolation and structure determination of novel fluoroindolocarbazoles from Saccharothrix aerocolonigenes ATCC 39243.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Biosynthesis of violacein: intact incorporation of the tryptophan molecule on the oxindole side, with intramolecular rearrangement of the indole ring on the 5-hydroxyindole side.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Crystal structure of the reduced form of p-hydroxybenzoate hydroxylase refined at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

The mobile flavin of 4-OH benzoate hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A hydroxylase-like gene product contributes to synthesis of a polyketide spore pigment in Streptomyces halstedii

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Molecular evolution of P450 superfamily and P450-containing monooxygenase systems

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Identification and Analysis of the Balhimycin Biosynthetic Gene Cluster and Its Use for Manipulating Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Conservation of the pyrrolnitrin biosynthetic gene cluster among six pyrrolnitrin-producing strains.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Isolation of a bromo analog of rebeccamycin from Saccharothrix aerocolonigenes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: a prototype of a new Flavin:NAD(P)H reductase subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Identification of a flavin:NADH oxidoreductase involved in the biosynthesis of actinorhodin. Purification and characterization of the recombinant enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Comparative molecular analysis of Na+/H+ exchangers: a unified model for Na+/H+ antiport?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Natural Metabolic Diversity Encoded by the Enterocin Biosynthesis Gene Cluster

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A subfamily of MalT-related ATP-dependent regulators in the LuxR family.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2).

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency, stereoselectivity and regulation with implications for function.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A novel fusidic acid resistance gene from Streptomyces lividans 66 encodes a highly specific esterase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Promoter constructions for efficient secretion expression in Streptomyces lividans.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Synthesis of N-alkyl substituted indolocarbazoles as potent inhibitors of human cytomegalovirus replication

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Lambdoid phages that simplify the recovery of in vitro recombinants

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

DNA sequencing with chain-terminating inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

A comprehensive set of sequence analysis programs for the VAX

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900126-6

7 January 2021

10.1016/S1074-5521(02)00126-6

Identifiers

DOI

1 reference

28 November 2017

1 reference