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Renal cancer: oxygen meets metabolism
scientific article published on 3 March 2012
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Europe PubMed Central
PMC publication ID
3334413
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
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25 January 2020
title
Renal cancer: oxygen meets metabolism
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
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25 January 2020
author
Volker H. Haase
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
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25 January 2020
author name string
Volker H Haase
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1
1 reference
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Europe PubMed Central
PMC publication ID
3334413
retrieved
11 August 2017
language of work or name
English
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publication date
3 March 2012
1 reference
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Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Experimental Cell Research
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stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
318
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Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
1057-1067
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stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
cites work
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
VHL inactivation induces HEF1 and Aurora kinase A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxic regulation of erythropoiesis and iron metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Mitochondrial metabolism and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia-inducible factor 2 regulates hepatic lipid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Regulation of endocytosis via the oxygen-sensing pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The VHL tumor suppressor and HIF: insights from genetic studies in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Screening, diagnosis, and treatment of cancer in long-term dialysis patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
pVHL and GSK3beta are components of a primary cilium-maintenance signalling network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Role of primary cilia in the pathogenesis of polycystic kidney disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Sorafenib in advanced clear-cell renal-cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Primary cilium formation requires von hippel-lindau gene function in renal-derived cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
p53 stabilization and transactivation by a von Hippel-Lindau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia-inducible factors in the kidney
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Integration of oxygen signaling at the consensus HRE.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Role of VHL gene mutation in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Oxygen sensing by HIF hydroxylases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Searching for the hereditary causes of renal-cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Analysis of the Birt-Hogg-Dubé (BHD) tumour suppressor gene in sporadic renal cell carcinoma and colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
von Hippel-Lindau disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
27 July 2018
pH control mechanisms of tumor survival and growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Understanding the Warburg effect: the metabolic requirements of cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
The tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Regulation of E-cadherin expression by VHL and hypoxia-inducible factor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene and VHL-haplotype analysis in patients with presumable congenital erythrocytosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Lack of mutation of the folliculin gene in sporadic chromophobe renal cell carcinoma and renal oncocytoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Inactivation of BHD in sporadic renal tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
Analysis of the TSC1 and TSC2 genes in sporadic renal cell carcinomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334413
retrieved
24 September 2018
The Mainz Classification of Renal Cell Tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Identification of the von Hippel-Lindau disease tumor suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Genotype-phenotype correlations in von Hippel-Lindau disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Renal cysts, renal cancer and von Hippel-Lindau disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Collagen matrix assembly is driven by the interaction of von Hippel-Lindau tumor suppressor protein with hydroxylated collagen IV alpha 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.026
retrieved
7 January 2021
Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22406000
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.YEXCR.2012.02.026
1 reference
stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PMC publication ID
3334413
1 reference
stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed publication ID
22406000
1 reference
stated in
Europe PubMed Central
PMC publication ID
3334413
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22406000%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
ResearchGate publication ID
221692011
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