(Q42413615)

30 October 2017

Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress (English)

1 reference

30 October 2017

4

1 reference

30 October 2017

Scott M Welford

1

1 reference

30 October 2017

Mary Jo Dorie

series ordinal

2

1 reference

30 October 2017

Xiaofeng Li

series ordinal

3

1 reference

30 October 2017

Amato J Giaccia

series ordinal

5

1 reference

30 October 2017

language of work or name

English

0 references

publication date

2 August 2010

1 reference

Molecular and Cellular Biology

30 October 2017

1 reference

30 October 2017

30

1 reference

30 October 2017

19

1 reference

30 October 2017

4595-4603

1 reference

The impact of O2 availability on human cancer

30 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

DNA double-strand breaks: a potential causative factor for mammalian aging?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Exposure of human diploid fibroblasts to hypoxia extends proliferative life span

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

HIF1alpha delays premature senescence through the activation of MIF.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

BRAFE600-associated senescence-like cell cycle arrest of human naevi

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oxygen: modulator of metabolic zonation and disease of the liver

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

A proinflammatory cytokine inhibits p53 tumor suppressor activity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oxygen toxicity: a radical explanation.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Nephrotoxicity of Paraquat in Man

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

A negative feedback signaling network underlies oncogene-induced senescence

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

Oxygen sensing by primary cardiac fibroblasts: a key role of p21(Waf1/Cip1/Sdi1).

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2950534

The oxygen supply of the rat kidney: Measurements of intrarenalpO2

16 August 2018

1 reference

12 December 2020

Low oxygen concentration extends the lifespan of cultured human diploid cells

1 reference

12 December 2020

Growth of functional primary cultures of kidney epithelial cells in defined medium

1 reference

12 December 2020

Histochemical evaluation of mouse and rat kidneys with lectin-horseradish peroxidase conjugates

1 reference

12 December 2020

Pharmacokinetic profile of paraquat following intravenous administration to the rabbit

1 reference

12 December 2020

Kinetics of Toxic Doses of Paraquat and the Effects of Hemoperfusion in the Dog

1 reference

12 December 2020

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

12 December 2020

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 December 2020

The cytotoxic effect of paraquat to isolated renal proximal tubular segments from rabbits

1 reference

12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.01618-09

1 reference

30 October 2017

1 reference

30 October 2017

1 reference