(Q35917834)

11 August 2017

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title

Proteomics analysis in Alzheimer's disease: new insights into mechanisms of neurodegeneration (English)

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11 August 2017

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1

D Allan Butterfield

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11 August 2017

Debra Boyd-Kimball

2

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11 August 2017

publication date

1 January 2004

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International Review of Neurobiology

11 August 2017

published in

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11 August 2017

volume

61

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11 August 2017

page(s)

159-188

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Mass spectrometry in proteomics

11 August 2017

cites work

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Oxidative modification of creatine kinase BB in Alzheimer's disease brain.

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7 January 2021

Protein oxidation in the brain in Alzheimer's disease

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7 January 2021

The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease

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7 January 2021

The use of seldi proteinchip arrays to monitor production of Alzheimer's betaamyloid in transfected cells.

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7 January 2021

Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease

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7 January 2021

Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.

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7 January 2021

An improved formulation of SYPRO Ruby protein gel stain: comparison with the original formulation and with a ruthenium II tris (bathophenanthroline disulfonate) formulation

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7 January 2021

The metallobiology of Alzheimer's disease

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7 January 2021

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

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7 January 2021

Amyloid &#946;-Peptide [1-42]-Associated Free Radical-Induced Oxidative Stress And Neurodegeneration in Alzheimers Disease Brain: Mechanisms and Consequences

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7 January 2021

Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain

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7 January 2021

Proteomics for the identification of specifically oxidized proteins in brain: technology and application to the study of neurodegenerative disorders

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7 January 2021

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

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7 January 2021

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

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7 January 2021

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

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7 January 2021

Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration

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7 January 2021

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

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7 January 2021

A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.

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7 January 2021

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

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7 January 2021

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

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7 January 2021

Proteomic identification of nitrated proteins in Alzheimer's disease brain

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7 January 2021

Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl-terminal hydrolase L-1, reveals oxidation of key proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Anti-apoptotic proteins are oxidized by Abeta25-35 in Alzheimer's fibroblasts.

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Alteration of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Expression of apoptosis related proteins in brains of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Proteome analysis by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Analysis of proteins from membrane-enriched cerebellar preparations by two-dimensional gel electrophoresis and mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Caspase activation in the limbic cortex of subjects with early Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Analysis of the mouse proteome. (I) Brain proteins: separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Cholinergic function and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Phosphoprotein isotope-coded affinity tag approach for isolating and quantitating phosphopeptides in proteome-wide analyses

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Advances in protein solubilisation for two-dimensional electrophoresis

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Improved protein solubility in two-dimensional electrophoresis using tributyl phosphine as reducing agent.

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Preparative two-dimensional gel electrophoresis at alkaline pH using narrow range immobilized pH gradients

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Methods for fractionation, separation and profiling of proteins and peptides

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification

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https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Advances in Alzheimer's disease

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7 January 2021

Impaired proteasome function in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Brain alpha-endosulfine is manifold decreased in brains from patients with Alzheimer's disease: a tentative marker and drug target?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The reduction of NADH ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Decreased levels of complex III core protein 1 and complex V beta chain in brains from patients with Alzheimer's disease and Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Phosphospecific proteolysis for mapping sites of protein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

An Introduction to Quadrupole Ion Trap Mass Spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Oxidative stress hypothesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Two-dimensional electrophoresis of membrane proteins using immobilized pH gradients.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Current trends in differential expression proteomics: isotopically coded tags

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Preparative two-dimensional gel electrophoresis of membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Species analysis of metallothionein isoforms in human brain cytosols by use of capillary electrophoresis hyphenated to inductively coupled plasma-sector field mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Phosphoprotein isotope-coded solid-phase tag approach for enrichment and quantitative analysis of phosphopeptides from complex mixtures.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Use of thiourea to increase the solubility of membrane proteins in two-dimensional electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The substantia innominata in Alzheimer's disease: an histochemical and biochemical study of cholinergic marker enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Contribution of neuroimaging in the diagnosis of Alzheimer's disease and other dementias

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Proteomic analysis of the brain in Alzheimer’s disease: Molecular phenotype of a complex disease process

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Brain t-complex polypeptide 1 (TCP- 1) related to its natural substrate beta1 tubulin is decreased in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Deciphering the genetic basis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Presenilin, Notch, and the genesis and treatment of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

High-throughput proteomic-based identification of oxidatively induced protein carbonylation in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Proteomic analysis of the synaptic plasma membrane fraction isolated from rat forebrain.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Differential expression of brain proteins in glycogen synthase kinase-3 transgenic mice: a proteomics point of view

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Proteomics analysis of the neurodegeneration in the brain of tau transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Analysis of brain proteins in Alzheimer's disease using high-resolution two-dimensional gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

The inhibitory and facilitatory actions of amyloid-beta peptides on nicotinic ACh receptors and AMPA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Proteomic profiling and neurodegeneration in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Multidimensional nano-HPLC for analysis of protein complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Multi-dimensional liquid phase based separations in proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

A method for the comprehensive proteomic analysis of membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Changes of voltage-dependent anion-selective channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2804%2961007-5

7 January 2021

10.1016/S0074-7742(04)61007-5

Identifiers

DOI

1 reference

11 August 2017

1 reference