(Q35980667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Development of Small Molecules that Specifically Inhibit the D-loop Activity of RAD51 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

2

1 reference

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31 March 2020

author name string

Wei Lv

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Michal Pawlowski

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Philip P Connell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Alan P Kozikowski

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

language of work or name

English

0 references

publication date

21 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medicinal Chemistry

31 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

page(s)

4511-4525

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5473336/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist

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Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

2 October 2017

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Targeting the homologous recombination pathway by small molecule modulators

2 October 2017

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Targeting homologous recombination-mediated DNA repair in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.

2 October 2017

1 reference

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Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis

2 October 2017

1 reference

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RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells

2 October 2017

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Inhibition of homologous recombination in human cells by targeting RAD51 recombinase

2 October 2017

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

2 October 2017

1 reference

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DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

2 October 2017

1 reference

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Use of the Rad51 promoter for targeted anti-cancer therapy

2 October 2017

1 reference

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A chemical compound that stimulates the human homologous recombination protein RAD51

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

The consequences of Rad51 overexpression for normal and tumor cells

2 October 2017

1 reference

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Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin.

2 October 2017

1 reference

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Genetic steps of mammalian homologous repair with distinct mutagenic consequences

2 October 2017

1 reference

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Synthesis, antimalarial activity, and molecular modeling of new pyrrolo[1,2-a]quinoxalines, bispyrrolo[1,2-a]quinoxalines, bispyrido[3,2-e]pyrrolo[1,2-a]pyrazines, and bispyrrolo[1,2-a]thieno[3,2-e]pyrazines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Elevated levels of Rad51 recombination protein in tumor cells.

2 October 2017

1 reference

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BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

2 October 2017

1 reference

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Homologous recombinational repair of DNA ensures mammalian chromosome stability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

2 October 2017

1 reference

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Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Homologous recombinational repair vis-à-vis chlorambucil resistance in chronic lymphocytic leukemia

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5473336

Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo[1,2-a]quinoxalines as antileishmanial agents

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27049177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27049177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACS.JMEDCHEM.5B01762

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27049177%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

27049177

1 reference