(Q35986327)

11 August 2017

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors (English)

1 reference

11 August 2017

Sharanya Sivanand

4

0 references

Jung-Mo Ahn

object named as

Jung-Mo Ahn

5

0 references

Betty S Pace

object named as

Betty S Pace

6

0 references

author name string

Levi Makala

1

1 reference

PMCID

3359661

11 August 2017

Salvatore Di Maro

2

1 reference

PMCID

3359661

11 August 2017

Tzu-Fang Lou

3

1 reference

11 August 2017

14 May 2012

1 reference

11 August 2017

1 reference

11 August 2017

2012

1 reference

11 August 2017

428137

1 reference

Creative Commons Attribution 3.0 Unported

11 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

2 October 2017

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Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole

2 October 2017

1 reference

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Induction of basophilic and eosinophilic differentiation in the human leukemic cell line KU812.

2 October 2017

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Efficient solid-phase synthesis of FK228 analogues as potent antitumoral agents

2 October 2017

1 reference

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A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger

2 October 2017

1 reference

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Improved total synthesis of the potent HDAC inhibitor FK228 (FR-901228)

2 October 2017

1 reference

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Hematopoietic cell transplantation for thalassemia and sickle cell disease: past, present and future

2 October 2017

1 reference

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The yin and yang of stem cell gene therapy: insights into hematopoiesis, leukemogenesis, and gene therapy safety

2 October 2017

1 reference

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Role of epigenetic modifications in normal globin gene regulation and butyrate-mediated induction of fetal hemoglobin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Histone deacetylase inhibitor FK228 is a potent inducer of human fetal hemoglobin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Short-chain fatty acids induce gamma-globin gene expression by displacement of a HDAC3-NCoR repressor complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Histone deacetylase inhibitors in programmed cell death and cancer therapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Do protein motifs read the histone code?

2 October 2017

1 reference

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Histone deacetylase inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

The role of hydroxyurea in the management of sickle cell disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Histone deacetylase inhibitors as new cancer drugs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice.

2 October 2017

1 reference

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Acetylation of a specific promoter nucleosome accompanies activation of the epsilon-globin gene by beta-globin locus control region HS2.

2 October 2017

1 reference

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Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Novel in vitro assay for the detection of pharmacologic inducers of fetal hemoglobin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Butyric acid: a small fatty acid with diverse biological functions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Thalassemia: The consequences of unbalanced hemoglobin synthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

A new antifungal antibiotic, trichostatin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Arabinosylcytosine Induces Fetal Hemoglobin in Baboons by Perturbing Erythroid Cell Differentiation Kinetics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Bipotential cell differentiation of KU-812: evidence of a hybrid cell line that differentiates into basophils and macrophage-like cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors

11 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Identification of thiols and glutathione conjugates of depsipeptide FK228 (FR901228), a novel histone protein deacetylase inhibitor, in the blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Differential modulation of signaling pathways and apoptosis of ras-transformed 10T1/2 cells by the depsipeptide FR901228.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

A new leukemia cell line with Philadelphia chromosome characterized as basophil precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Clinical effectiveness of decitabine in severe sickle cell disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Induction of fetal hemoglobin synthesis by valproate: modulation of MAP kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Fetal hemoglobin induction by the histone deacetylase inhibitor, scriptaid.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3359661

Backbone Amide Linker (BAL) Strategy for Solid-Phase Synthesis of C-Terminal-Modified and Cyclic Peptides1,2,3

24 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F428137

Treatment of severe β-thalassemia (patients) with myleran

21 January 2018

1 reference

12 December 2020

Treatment of baboon with vinblastine: insights into the mechanisms of pharmacologic stimulation of Hb F in the adult

1 reference

12 December 2020

On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC

1 reference

12 December 2020

Augmentation of Fetal-Hemoglobin Production in Anemic Monkeys by Hydroxyurea

1 reference

12 December 2020

Stimulation of fetal hemoglobin production by short chain fatty acids

1 reference

12 December 2020

Erythroid progenitor proliferation is stimulated by phenoxyacetic and phenylalkyl acids

1 reference

12 December 2020

Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/428137

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

3359661