(Q35997721)

11 August 2017

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title

Erythropoietin on a tightrope: balancing neuronal and vascular protection between intrinsic and extrinsic pathways (English)

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11 August 2017

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3

Kenneth Maiese

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11 August 2017

Faqi Li

1

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PubMed ID

15627815

11 August 2017

Zhao Zhong Chong

series ordinal

2

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11 August 2017

1 November 2004

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11 August 2017

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11 August 2017

13

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11 August 2017

6

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11 August 2017

265-289

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Erythropoietin in the control of red cell production

11 August 2017

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Isolation and characterization of genomic and cDNA clones of human erythropoietin

21 January 2018

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Comparative structural study of N-linked oligosaccharides of urinary and recombinant erythropoietins

21 January 2018

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The role of carbohydrate in recombinant human erythropoietin

21 January 2018

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Erythropoietin stimulates proliferation and interferes with differentiation of myoblasts.

21 January 2018

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Human, nonhuman primate, and rat pancreatic islets express erythropoietin receptors

21 January 2018

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Erythropoietin: cytoprotection in vascular and neuronal cells

21 January 2018

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Angiogenesis and plasticity: role of erythropoietin in vascular systems

21 January 2018

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Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin

21 January 2018

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Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA.

21 January 2018

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Regulated human erythropoietin receptor expression in mouse brain.

21 January 2018

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Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

21 January 2018

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A potential role for erythropoietin in focal permanent cerebral ischemia in mice.

21 January 2018

1 reference

Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer

21 January 2018

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Purification and characterization of hypoxia-inducible factor 1

21 January 2018

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

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Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons.

21 January 2018

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Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis

21 January 2018

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Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture

21 January 2018

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Erythropoietin and bone morphogenetic protein 7 mediate ascorbate-induced dopaminergic differentiation from embryonic mesencephalic precursors

21 January 2018

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Neurotrophic effect of hematopoietic cytokines on cholinergic and other neurons in vitro.

21 January 2018

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In vivo evidence that erythropoietin protects neurons from ischemic damage

21 January 2018

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Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats

21 January 2018

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Erythropoietin prevents place navigation disability and cortical infarction in rats with permanent occlusion of the middle cerebral artery.

21 January 2018

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Single intravenous injection of naked plasmid DNA encoding erythropoietin provides neuroprotection in hypoxia-ischemia rats

21 January 2018

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Beneficial effects of systemic administration of recombinant human erythropoietin in rabbits subjected to subarachnoid hemorrhage

21 January 2018

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Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: effect on lipid peroxidation and early ultrastructural findings.

21 January 2018

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Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades

21 January 2018

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HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

21 January 2018

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Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury

21 January 2018

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Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability.

21 January 2018

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Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases

21 January 2018

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Mechanisms of angiogenesis

21 January 2018

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Intussusceptive angiogenesis--the alternative to capillary sprouting

21 January 2018

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

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Erythropoietin and VEGF exhibit equal angiogenic potential

21 January 2018

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Protection against cisplatin-induced nephrotoxicity by recombinant human erythropoietin

21 January 2018

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Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury.

21 January 2018

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Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts.

21 January 2018

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Erythropoietin in cardiovascular diseases.

21 January 2018

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Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway.

21 January 2018

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Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats

21 January 2018

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Changes in left ventricular size, wall thickness, and function in anemic patients treated with recombinant human erythropoietin

21 January 2018

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Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling

21 January 2018

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The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study

21 January 2018

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The effect of correction of anaemia in diabetics and non-diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron

21 January 2018

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Annexin I Is an Endogenous Ligand that Mediates Apoptotic Cell Engulfment

21 January 2018

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

21 January 2018

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Fractalkine and fractalkine receptors in human neurons and glial cells

21 January 2018

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Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

21 January 2018

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Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts

21 January 2018

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Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation

21 January 2018

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Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells

21 January 2018

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Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain

21 January 2018

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Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways

21 January 2018

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Akt1 protects against inflammatory microglial activation through maintenance of membrane asymmetry and modulation of cysteine protease activity

21 January 2018

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Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6.

21 January 2018

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Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition.

21 January 2018

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Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway.

21 January 2018

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Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

21 January 2018

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Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

21 January 2018

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Time course of microglia activation and apoptosis in various brain regions after permanent focal cerebral ischemia in mice.

21 January 2018

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Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms.

21 January 2018

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Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8.

21 January 2018

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Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis

21 January 2018

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Pleckstrin homology domains and the cytoskeleton

21 January 2018

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AKT1 drives endothelial cell membrane asymmetry and microglial activation through Bcl-xL and caspase 1, 3, and 9

21 January 2018

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Release of annexin V-binding membrane microparticles from cultured human umbilical vein endothelial cells after treatment with camptothecin

21 January 2018

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Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death

21 January 2018

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Erythropoietin depresses nitric oxide synthase expression by human endothelial cells

21 January 2018

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Chemical hypoxia-ischemia induces apoptosis in cerebromicrovascular endothelial cells

21 January 2018

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Apoptosis in Alzheimer's disease--an update

21 January 2018

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Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

21 January 2018

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Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta

21 January 2018

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Molecular targets to promote central nervous system regeneration

21 January 2018

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Essential cellular regulatory elements of oxidative stress in early and late phases of apoptosis in the central nervous system

21 January 2018

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Lubeluzole protects hippocampal neurons from excitotoxicity in vitro and reduces brain damage caused by ischemia

21 January 2018

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PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

21 January 2018

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Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin

21 January 2018

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Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors

21 January 2018

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Activation and inhibition of erythropoietin receptor function: role of receptor dimerization

21 January 2018

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

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Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

21 January 2018

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The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain

21 January 2018

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Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia

21 January 2018

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Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

21 January 2018

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cDNA cloning and functional analysis of a truncated STAT5a protein from autonomously growing FDCP-1 cells

21 January 2018

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

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Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

21 January 2018

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Akt1 regulates a JNK scaffold during excitotoxic apoptosis

21 January 2018

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Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells

21 January 2018

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Crosstalk between p38, Hsp25 and Akt in spinal motor neurons after sciatic nerve injury

21 January 2018

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Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity

21 January 2018

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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

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The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential

21 January 2018

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Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells

21 January 2018

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Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

21 January 2018

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Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

21 January 2018

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Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism

21 January 2018

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Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity

21 January 2018

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Erythropoietin exerts anti-apoptotic effects on rat microglial cells in vitro.

21 January 2018

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Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss

21 January 2018

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Protective effect of heat shock proteins in the nervous system

21 January 2018

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Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

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Apoptosis-regulating proteins as targets for drug discovery

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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Inhibition of JNK activation through NF-kappaB target genes

21 January 2018

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Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

21 January 2018

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

21 January 2018

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Apoptosis Occurs in a New Model of Thermal Brain Injury

21 January 2018

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NF-kappaB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression

21 January 2018

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Protective effect of erythropoietin in neonatal hypoxic ischemia in mice

21 January 2018

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Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.

21 January 2018

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Prevention of nitric oxide-induced neuronal injury through the modulation of independent pathways of programmed cell death.

21 January 2018

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Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

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The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

21 January 2018

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

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Caspase activation: revisiting the induced proximity model

21 January 2018

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The CARD domain: a new apoptotic signalling motif

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

21 January 2018

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Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process

21 January 2018

1 reference

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

21 January 2018

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Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein

21 January 2018

1 reference

Neuroprotection of immortalized hippocampal neurones by brain-derived neurotrophic factor and Raf-1 protein kinase: role of extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase

21 January 2018

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

21 January 2018

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Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

21 January 2018

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Differential MAP kinases activation during semaphorin3A-induced repulsion or apoptosis of neural progenitor cells

21 January 2018

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Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury

21 January 2018

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Serine/threonine protein kinases and apoptosis.

21 January 2018

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A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

21 January 2018

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Protein kinase C alpha controls erythropoietin receptor signaling

21 January 2018

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Acute cardioprotective effects of erythropoietin in infant rabbits are mediated by activation of protein kinases and potassium channels

21 January 2018

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Erythropoietin modulates intracellular calcium in a human neuroblastoma cell line.

21 January 2018

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Effects of erythropoietin on neuronal activity.

21 January 2018

1 reference

Epoetin alfa. Clinical evolution of a pleiotropic cytokine

21 January 2018

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Blood pressure response to erythropoietin injection in hemodialysis and predialysis patients.

21 January 2018

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Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway

21 January 2018

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Nitric oxide metabolism in erythropoietin-induced hypertension: effect of calcium channel blockade.

21 January 2018

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Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin.

21 January 2018

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Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice

21 January 2018

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Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization

21 January 2018

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Effect of active oxygen radicals on protein and carbohydrate moieties of recombinant human erythropoietin

21 January 2018

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/citations/10.3109/10715769709065769

Identifiers

DOI

10.1159/000081963

1 reference

11 August 2017

1 reference

PubMed ID

15627815