(Q36003890)

11 August 2017

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title

Involvement of quinolinic acid in AIDS dementia complex (English)

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11 August 2017

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Stephen J Kerr

2

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Gilles J. Guillemin

object named as

Gilles J Guillemin

series ordinal

1

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Bruce J Brew

object named as

Bruce J Brew

series ordinal

3

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ORCID Public Data File 2021

publication date

1 January 2005

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11 August 2017

Neurotoxicity Research

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11 August 2017

7

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11 August 2017

1-2

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11 August 2017

103-123

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https://scigraph.springernature.com/pub.10.1007/bf03033781

11 August 2017

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cites work

Tryptophan metabolism in rabbits

2 references

https://api.crossref.org/works/10.1007%2FBF03033781

21 January 2018

12 December 2020

Tryptophan metabolism along the kynurenine pathway in rats

2 references

https://api.crossref.org/works/10.1007%2FBF03033781

21 January 2018

12 December 2020

Quinolinic acid neurotoxicity in the nucleus basalis antagonized by kynurenic acid

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Cerebrospinal fluid beta 2 microglobulin in patients infected with human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Quinolinic acid in the cerebrospinal fluid of children with symptomatic human immunodeficiency virus type 1 disease: relationships to clinical status and therapeutic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Neopterin and interferon-gamma in serum and cerebrospinal fluid of patients with HIV-associated neurologic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Expression of the kynurenine pathway enzymes in human microglia and macrophages

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FBF03033781

21 January 2018

12 December 2020

A beta 1-42 induces production of quinolinic acid by human macrophages and microglia

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Neuroactive kynurenines in Lyme borreliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Human microglia convert l-tryptophan into the neurotoxin quinolinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Cytokines and HIV-1: interactions and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

The role of monocytes and macrophages in the pathogenesis of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

The AIDS dementia complex: II. Neuropathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Purification of quinolinic acid phosphoribosyltransferase from rat liver and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Zidovudine treatment prolongs survival and decreases virus load in the central nervous system of rhesus macaques infected perinatally with simian immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Increased human immunodeficiency virus (HIV) type 1 DNA content and quinolinic acid concentration in brain tissues from patients with HIV encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Subtypes of NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033781

Activated human microglia produce the excitotoxin quinolinic acid

21 January 2018

1 reference

12 December 2020

HIV-1 propagates in human neuroblastoma cells

1 reference

12 December 2020

Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vitro and in vivo studies

1 reference

12 December 2020

The relationship between AIDS dementia complex and the presence of macrophage tropic and non-syncytium inducing isolates of human immunodeficiency virus type 1 in the cerebrospinal fluid.

1 reference

12 December 2020

Atorvastatin suppresses interferon-gamma -induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines.

1 reference

12 December 2020

Tryptophan and the immune response

1 reference

12 December 2020

Brain tryptophan. Normal and disturbed control

1 reference

12 December 2020

CPI-1189 attenuates effects of suspected neurotoxins associated with AIDS dementia: a possible role for ERK activation

1 reference

12 December 2020

Chemokine coreceptor usage by diverse primary isolates of human immunodeficiency virus type 1

1 reference

12 December 2020

Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury

1 reference

12 December 2020

The glutamate receptor ion channels

1 reference

12 December 2020

Gp120 can revert antagonism at the glycine site of NMDA receptors mediating GABA release from cultured hippocampal neurons

1 reference

12 December 2020

Expression of the kynurenine enzymes in macrophages and microglial cells: regulation by immune modulators

1 reference

12 December 2020

The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures

1 reference

12 December 2020

N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx

1 reference

12 December 2020

Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

1 reference

12 December 2020

Stimulation of enveloped virus infection by beta-amyloid fibrils

1 reference

12 December 2020

Neuroprotective effects of kynurenine-3-hydroxylase inhibitors in models of brain ischemia

1 reference

12 December 2020

Endogenous neurotoxins from tryptophan

1 reference

12 December 2020

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

1 reference

12 December 2020

Quinolinic acid is a potent lipid peroxidant in rat brain homogenates

1 reference

12 December 2020

The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (-) 2-amino-7-phosphonoheptanoic acid

1 reference

12 December 2020

Increased neopterin levels in brains of patients with human immunodeficiency virus type 1 infection

1 reference

12 December 2020

Chemokine immunobiology in HIV-1 pathogenesis

1 reference

12 December 2020

Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia

1 reference

12 December 2020

Differential induction of chemokines in human microglia by type I and II interferons

1 reference

12 December 2020

Differential vulnerability of central neurons of the rat to quinolinic acid

1 reference

12 December 2020

HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy

1 reference

12 December 2020

Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

1 reference

12 December 2020

Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS.

1 reference

12 December 2020

Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors

1 reference

12 December 2020

Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection

1 reference

12 December 2020

Clinical-neuropathologic correlation in HIV-associated dementia

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12 December 2020

Cytokine expression in the brain during the acquired immunodeficiency syndrome

1 reference

12 December 2020

Tumor necrosis factor alpha and transforming growth factor beta upregulate astrocyte expression of monocyte chemoattractant protein-1

1 reference

12 December 2020

MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis

1 reference

12 December 2020

Marked improvement in survival following AIDS dementia complex in the era of highly active antiretroviral therapy

1 reference

12 December 2020

Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes

1 reference

12 December 2020

Neuronal injury associated with HIV-1: approaches to treatment

1 reference

12 December 2020

N-Methyl-D-aspartate receptor subtype-selectivity of homoquinolinate: an electrophysiological and radioligand binding study using both native and recombinant receptors

1 reference

12 December 2020

Correlation between neurological progression and astrocyte apoptosis in HIV-associated dementia

1 reference

12 December 2020

Endogenous kynurenines as targets for drug discovery and development

1 reference

12 December 2020

Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia

1 reference

12 December 2020

Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia

1 reference

12 December 2020

Immunopathogenesis of HIV-associated dementia

1 reference

12 December 2020

Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain

1 reference

12 December 2020

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.

1 reference

12 December 2020

Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis-necrosis continuum.

1 reference

12 December 2020

CSF quinolinic acid levels are determined by local HIV infection: cross-sectional analysis and modelling of dynamics following antiretroviral therapy.

1 reference

12 December 2020

Quinolinate neurotoxicity in cortical cell culture.

1 reference

12 December 2020

Cytokines and HIV infection: is AIDS a tumor necrosis factor disease?

1 reference

12 December 2020

Inflammatory processes in amyotrophic lateral sclerosis

1 reference

12 December 2020

Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes

1 reference

12 December 2020

Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains

1 reference

12 December 2020

Gamma interferon expression and major histocompatibility complex induction during measles and vesicular stomatitis virus infections of the brain

1 reference

12 December 2020

Astrocyte activation and apoptosis: their roles in the neuropathology of HIV infection

1 reference

12 December 2020

The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia

1 reference

12 December 2020

HIV-1 associated dementia: clinical features and pathogenesis.

1 reference

12 December 2020

Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children

1 reference

12 December 2020

Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.

1 reference

12 December 2020

Prevention of allogeneic fetal rejection by tryptophan catabolism

1 reference

12 December 2020

AIDS and the brain: is there a chemokine connection?

1 reference

12 December 2020

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity

1 reference

12 December 2020

N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition

1 reference

12 December 2020

Neurocytotoxity of quinolinic acid in human brain cultures

1 reference

12 December 2020

Restricted HIV-1 infection of human astrocytes: potential role of nef in the regulation of virus replication.

1 reference

12 December 2020

Glia: the not so innocent bystanders.

1 reference

12 December 2020

Developmental changes in arachidonic acid potentiation of NMDA currents in cortical neurones.

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12 December 2020

The preferred route of kynurenine metabolism in the rat

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12 December 2020

[Quinolinic acid depolarizes the spinal motoneurons of newborn rats by activating NMDA receptors]

1 reference

12 December 2020

Expression of beta-chemokines and chemokine receptors in human fetal astrocyte and microglial co-cultures: potential role of chemokines in the developing CNS.

1 reference

12 December 2020

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

1 reference

12 December 2020

Quinolinate differentiates between forebrain and cerebellar NMDA receptors

1 reference

12 December 2020

Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method

1 reference

12 December 2020

Dopamine and glutamate control each other's release in the basal ganglia: a microdialysis study of the entopeduncular nucleus and substantia nigra

1 reference

12 December 2020

The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity

1 reference

12 December 2020

Quinolinate and kainate neurotoxicity in neostriatal cultures is potentiated by co-culturing with neocortical neurons.

1 reference

12 December 2020

HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones

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12 December 2020

Elevated alpha-tumor necrosis factor levels in spinal fluid from HIV-1-infected patients with central nervous system involvement

1 reference

12 December 2020

Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons.

1 reference

12 December 2020

Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists.

1 reference

12 December 2020

Enzyme activities along the kynurenine pathway in mice.

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12 December 2020

Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines

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12 December 2020

Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. AIDS Clinical Trials Group

1 reference

12 December 2020

Enzyme activities of tryptophan metabolism along the kynurenine pathway in various species of animals

1 reference

12 December 2020

Production and function of monocyte chemoattractant protein-1 and other beta-chemokines in murine glial cells

1 reference

12 December 2020

Short- and long-term consequences of intracranial injections of the excitotoxin, quinolinic acid, as evidenced by GFA immunohistochemistry of astrocytes.

1 reference

12 December 2020

The messenger RNAs for the N-methyl-D-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain

1 reference

12 December 2020

Excitatory effects of kynurenine and its metabolites, amino acids and convulsants administered into brain ventricles: differences between rats and mice

1 reference

12 December 2020

Energetic dysfunction in quinolinic acid-lesioned rat striatum

1 reference

12 December 2020

Elevated IFN-gamma and decreased IL-2 gene expression are associated with HIV infection

1 reference

12 December 2020

Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products

1 reference

12 December 2020

Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1.

1 reference

12 December 2020

Neuronal loss in the frontal cortex in HIV infection

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12 December 2020

Quinolinic acid accumulation and functional deficits following experimental spinal cord injury

1 reference

12 December 2020

Quinolinic acid and active oxygens. Possible contribution of active Oxygens during cell death in the brain

1 reference

12 December 2020

Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent

1 reference

12 December 2020

Simian immunodeficiency virus mac251 infection of astrocytes

1 reference

12 December 2020

Cerebrospinal fluid beta 2-microglobulin in patients with AIDS dementia complex: an expanded series including response to zidovudine treatment

1 reference

12 December 2020

The kynurenine pathway and neurologic disease. Therapeutic strategies

1 reference

12 December 2020

Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction

1 reference

12 December 2020

Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures

1 reference

12 December 2020

NMDA and non-NMDA ionotropic glutamate receptors modulate striatal acetylcholine release via pre- and postsynaptic mechanisms.

1 reference

12 December 2020

Neuropathogenesis of acquired immunodeficiency syndrome dementia

1 reference

12 December 2020

Human immunodeficiency virus-associated dementia

1 reference

12 December 2020

Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system

1 reference

12 December 2020

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

1 reference

12 December 2020

An overview of AIDS dementia complex

1 reference

12 December 2020

The effect of quinolinate on rat brain lipid peroxidation is dependent on iron

1 reference

12 December 2020

Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes

1 reference

12 December 2020

Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine

1 reference

12 December 2020

Brain virus burden and indoleamine-2,3-dioxygenase expression during lentiviral infection of rhesus monkey are concomitantly lowered by 6-chloro-2',3'-dideoxyguanosine

1 reference

12 December 2020

Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients

1 reference

12 December 2020

Subchronic intraventricular infusion of quinolinic acid produces working memory impairment--a model of progressive excitotoxicity.

1 reference

12 December 2020

Kynurenine pathway enzymes in guinea pigs.

1 reference

12 December 2020

Upregulated expression of interleukin-8, RANTES and chemokine receptors in human astrocytic cells infected with HIV-1.

1 reference

12 December 2020

Quinolinate immunoreactivity in experimental rat brain tumors is present in macrophages but not in astrocytes.

1 reference

12 December 2020

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

1 reference

12 December 2020

The pharmacological manipulation of glutamate receptors and neuroprotection

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12 December 2020

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

1 reference

12 December 2020

Regulation of beta-chemokine mRNA expression in adult rat astrocytes by lipopolysaccharide, proinflammatory and immunoregulatory cytokines.

1 reference

12 December 2020

The envelope glycoprotein of HIV-1 alters NMDA receptor function.

1 reference

12 December 2020

Cytotoxicity of 3-hydroxykynurenine in a neuronal hybrid cell line

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12 December 2020

Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease

1 reference

12 December 2020

Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

1 reference

12 December 2020

Cytokine regulation of CC and CXC chemokine expression by human astrocytes.

1 reference

12 December 2020

Neuroinvasion by simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/microglia and intrathecal immune activation.

1 reference

12 December 2020

Biphasic effect of quinolinate on frog spinal, but not rat cortical, neurones: N-methyl-D-aspartate-like depolarisation and a novel type of hyperpolarisation.

1 reference

12 December 2020

Quinolinic acid induces oxidative stress in rat brain synaptosomes

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12 December 2020

Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival

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12 December 2020

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.

1 reference

12 December 2020

Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients

1 reference

12 December 2020

Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

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12 December 2020

Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl

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12 December 2020

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

1 reference

12 December 2020

Prevalence of Alzheimer plaques in AIDS.

1 reference

12 December 2020

Localization of quinolinic acid metabolizing enzymes in the rat brain. Immunohistochemical studies using antibodies to 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase

1 reference

12 December 2020

HIV infection of macrophages and pathogenesis of AIDS dementia complex: interaction of the host cell and viral genotype.

1 reference

12 December 2020

Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells

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12 December 2020

A mechanism for increased quinolinic acid formation following acute systemic immune stimulation.

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12 December 2020

Quinolinic acid production is related to macrophage tropic isolates of HIV-1.

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12 December 2020

Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia

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12 December 2020

Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques

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12 December 2020

Quinolinate is a weak excitant of cortical neurons in cell culture.

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12 December 2020

Evidence for a change in AIDS dementia complex in the era of highly active antiretroviral therapy and the possibility of new forms of AIDS dementia complex

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12 December 2020

T cell apoptosis by tryptophan catabolism

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12 December 2020

Central nervous system correlates of behavioral deficits following simian immunodeficiency virus infection

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12 December 2020

Spectrum of human immunodeficiency virus-associated neocortical damage

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12 December 2020

MK-801, an N-methyl-D-aspartate receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum

1 reference

12 December 2020

HIV in central nervous system and behavioral development: an HIV-2287 macaque model of AIDS.

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12 December 2020

Neuropharmacology of quinolinic and kynurenic acids

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12 December 2020

Quinolinic acid in culture media used for in vitro neurotoxicology studies

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12 December 2020

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase

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12 December 2020

Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein.

1 reference

12 December 2020

Tolerance, DCs and tryptophan: much ado about IDO

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12 December 2020

Synaptic plasticity and physiological interactions between dopamine and glutamate in the striatum

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12 December 2020

Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

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12 December 2020

Abnormal cerebral glucose metabolism in HIV-1 seropositive subjects with and without dementia.

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12 December 2020

The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits.

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12 December 2020

Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.

1 reference

12 December 2020

HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.

1 reference

12 December 2020

Distribution of quinolinic acid phosphoribosyltransferase in the human hippocampal formation and parahippocampal gyrus

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12 December 2020

Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice

1 reference

12 December 2020

Accumulation of beta-amyloid precursor protein in axons correlates with CNS expression of SIV gp41

1 reference

12 December 2020

Quantifying HIV-1 RNA Using the Polymerase Chain Reaction on Cerebrospinal Fluid and Serum of Seropositive Individuals With and Without Neurologic Abnormalities

1 reference

12 December 2020

Chemokine receptors and HIV-1: the fusion of two major research fields

1 reference

12 December 2020

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

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12 December 2020

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

12 December 2020

Axonal damage revealed by accumulation of beta-APP in HIV-positive individuals without AIDS.

1 reference

12 December 2020

U50,488 protection against HIV-1-related neurotoxicity: involvement of quinolinic acid suppression

1 reference

12 December 2020

Macrophage Activation Factors in the Brains of AIDS Patients

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12 December 2020

Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes

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12 December 2020

Quinolinic acid metabolism in the rat brain. Immunohistochemical identification of 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase in the hippocampal region

1 reference

12 December 2020

Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

1 reference

12 December 2020

Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

1 reference

12 December 2020

Cytokine dysregulation in HIV-associated neurological disease

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12 December 2020

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

12 December 2020

Cytokines and chemokines in HIV infection: implications for therapy.

1 reference

12 December 2020

Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120

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12 December 2020

Enhanced neuronal damage by co-administration of quinolinic acid and free radicals, and protection by adenosine A2A receptor antagonists

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12 December 2020

Evidence for bidirectional changes in nitric oxide synthase activity in the rat striatum after excitotoxically (quinolinic acid) induced degeneration

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12 December 2020

Neocortical damage during HIV infection

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12 December 2020

HIV blocked by chemokine antagonist

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12 December 2020

Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain

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12 December 2020

Immunohistochemical localization of quinolinic acid phosphoribosyltransferase in the human neostriatum

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12 December 2020

Early intrathecal events in rhesus macaques (Macaca mulatta) infected with pathogenic or nonpathogenic molecular clones of simian immunodeficiency virus

1 reference

12 December 2020

AIDS dementia complex and HIV-1 infection: a view from the clinic

1 reference

12 December 2020

Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin

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12 December 2020

Quinolinate potentiates the neurotoxicity of excitatory amino acids in hypoxic neuronal tissue in vitro.

1 reference

12 December 2020

Quinolinic acid phosphoribosyltransferase: preferential glial localization in the rat brain visualized by immunocytochemistry

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12 December 2020

Copper blocks quinolinic acid neurotoxicity in rats: contribution of antioxidant systems

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12 December 2020

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

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12 December 2020

NMDA receptors and ligands in the vertebrate CNS.

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12 December 2020

AIDS dementia complex and primary HIV brain infection

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12 December 2020

Reduction of serum melatonin levels in HIV-1-infected individuals' parallel disease progression: correlation with serum interleukin-12 levels

1 reference

12 December 2020

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

1 reference

12 December 2020

Protective effect of nimodipine against quinolinic acid-induced damage of rat hippocampus in vitro

1 reference

12 December 2020

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

12 December 2020

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients

1 reference

12 December 2020

Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system

1 reference

12 December 2020

AIDS dementia complex and HIV-1 brain infection: clinical-virological correlations

1 reference

12 December 2020

Prospective analysis of seizures occurring in human immunodeficiency virus type-1 infection

1 reference

12 December 2020

Activation of human microglial cells by HIV-1 gp41 and Tat proteins

1 reference

12 December 2020

Species heterogeneity between gerbils and rats: quinolinate production by microglia and astrocytes and accumulations in response to ischemic brain injury and systemic immune activation.

1 reference

12 December 2020

In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum

1 reference

12 December 2020

Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors

1 reference

12 December 2020

Chemokines and receptors in HIV encephalitis

1 reference

12 December 2020

The clinical spectrum and pathogenesis of HIV encephalopathy, myelopathy, and peripheral neuropathy

1 reference

12 December 2020

Effect of quinolinic acid on neurons in dissociated cultures of cells of different structures of the brain

1 reference

12 December 2020

Cytokine circuits in brain. Implications for AIDS dementia complex

1 reference

12 December 2020

Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites

1 reference

12 December 2020

Immunohistochemical identification of quinolinic acid phosphoribosyltransferase in glial cultures from rat brain

1 reference

12 December 2020

Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

1 reference

12 December 2020

Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma.

1 reference

12 December 2020

Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection.

1 reference

12 December 2020

Dopamine-glutamate interactions in the striatum: behaviourally relevant modification of excitotoxicity by dopamine receptor-mediated mechanisms.

1 reference

12 December 2020

Antioxidant treatment protects striatal neurons against excitotoxic insults

1 reference

12 December 2020

The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes

1 reference

12 December 2020

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

1 reference

12 December 2020

Differential stimulation of somatostatin but not neuropeptide Y gene expression by quinolinic acid in cultured cortical neurons

1 reference

12 December 2020

Neurotoxin quinolinic acid is selectively elevated in spinal cords of rats with experimental allergic encephalomyelitis

1 reference

12 December 2020

Differential production of and migratory response to beta chemokines by human microglia and astrocytes

1 reference

12 December 2020

Kynurenic acid protects against the neurochemical and behavioral effects of unilateral quinolinic acid injections into the nucleus basalis of rats

1 reference

12 December 2020

Characterization of striatal cultures with the effect of QUIN and NMDA.

1 reference

12 December 2020

Dopamine deficits in the brain: the neurochemical basis of parkinsonian symptoms in AIDS.

1 reference

12 December 2020

Cerebrospinal fluid neopterin in human immunodeficiency virus type 1 infection

1 reference

12 December 2020

HIV infection and pathogenesis: what about chemokines?

1 reference

12 December 2020

Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor

1 reference

12 December 2020

The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

1 reference

12 December 2020

HIV-1 gp120 does not induce Quinolinic acid production by macrophages.

1 reference

12 December 2020

Presentation and course of AIDS dementia complex: 10 years of follow-up in Amsterdam, The Netherlands.

1 reference

12 December 2020

Kynurenine pathway enzymes in different species of animals.

1 reference

12 December 2020

Rapid alterations in dendrite morphology during sublethal hypoxia or glutamate receptor activation

1 reference

12 December 2020

Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center

1 reference

12 December 2020

IL4 and IL10 as potent inhibitors of HIV1 replication in macrophages in vitro: a role for cytokines in the in vivo virus host range?

1 reference

12 December 2020

Quinolinic acid in patients with systemic lupus erythematosus and neuropsychiatric manifestations

1 reference

12 December 2020

Antibodies against microglia/brain macrophages in the cerebrospinal fluid of a patient with acute amyotrophic lateral sclerosis and presenile dementia

1 reference

12 December 2020

Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains

1 reference

12 December 2020

Quinolinic acid production by macrophages stimulated with IFN-gamma, TNF-alpha, and IFN-alpha.

1 reference

12 December 2020

Parallel decrease in neurotoxin quinolinic acid and soluble tumor necrosis factor receptor p75 in serum during highly active antiretroviral therapy of HIV type 1 disease

1 reference

12 December 2020

AIDS dementia complex

1 reference

12 December 2020

Endogenous protectant kynurenic acid in amyotrophic lateral sclerosis

1 reference

12 December 2020

Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex.

1 reference

12 December 2020

Progressive slowing of reaction time and increasing cerebrospinal fluid concentrations of quinolinic acid in HIV-infected individuals

1 reference

12 December 2020

HIV-1 infection of primary human neuroblasts

1 reference

12 December 2020

Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia.

1 reference

12 December 2020

Immunobiology of picolinic acid.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03033781

1 reference

release_mkg6ggczn5fsrbcoq2zlntoxf4

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mkg6ggczn5fsrbcoq2zlntoxf4

24 November 2022

mapped directly with Wikidata item

PubMed ID

15639803

1 reference

PubMed ID

15639803