(Q36006453)

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Physical contact with endothelial cells through β1- and β2- integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells.

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19 January 2020

Physical contact with endothelial cells through β1- and β2- integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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1 reference

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inferred from title

chronic lymphocytic leukemia

1 reference

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1

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19 January 2020

Jenny Bulgarelli

3

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19 January 2020

Silvia Martinelli

4

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19 January 2020

12

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19 January 2020

14

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19 January 2020

Roberto Marasca

15

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19 January 2020

Valeria Coluccio

9

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Valeria Coluccio

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19 January 2020

Goretta Bonacorsi

10

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Goretta Bonacorsi

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19 January 2020

Patrizia Zucchini

11

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Patrizia Zucchini

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19 January 2020

Stefania Fiorcari

2

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Stefania Fiorcari

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19 January 2020

6

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Silvia Deaglio

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19 January 2020

7

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Giulia Debbia

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19 January 2020

author name string

Ilaria Castelli

5

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19 January 2020

Marcella Fontana

8

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19 January 2020

Giuseppe Torelli

13

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19 January 2020

publication date

29 December 2011

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19 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

97

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19 January 2020

6

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Europe PubMed Central

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19 January 2020

952-960

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Nurture versus nature: the microenvironment in chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation andDe novoGene Transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Increased angiogenesis induced by chronic lymphocytic leukemia B cells is mediated by leukemia-derived Ang2 and VEGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Endoglin (CD105): a marker of tumor vasculature and potential target for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Bone biopsy derived marrow stromal elements rescue chronic lymphocytic leukemia B-cells from spontaneous and drug induced cell death and facilitates an "angiogenic switch".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

The clinical and biologic importance of neovascularization and angiogenic signaling pathways in chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

The endothelin axis: emerging role in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

The role of thrombospondin-1 in tumor progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Vascular-specific growth factors and blood vessel formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

Apoptosis and interleukin 7 gene expression in chronic B-lymphocytic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

2 October 2017

High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

27 July 2018

Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Increased expression of angiopoietin-2 characterizes early B-cell chronic lymphocytic leukemia with poor prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Prognostic value of enhanced bone marrow angiogenesis in early B-cell chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366665

23 September 2018

Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 expression on B-cell chronic lymphocytic leukemic cells is strongly correlated with vascular endothelial growth factor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation centres in B-cell malignant lymphoma, lymphocytic (B-CLL): an immunophenotypic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of thrombospondin receptor (CD36) in B-cell chronic lymphocytic leukemia as an indicator of tumor cell dissemination

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of CD23 in the proliferation centers of chronic lymphocytic leukemia in lymph nodes and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 dimers produced by endothelial cells inhibit apoptosis of B-chronic lymphocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis is increased in B-cell chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22207686

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3324/HAEMATOL.2011.054924

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22207686%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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