(Q36033195)

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NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes (English)

1 reference

Europe PubMed Central

11 August 2017

cyclic ADP-ribose

1 reference

ChEBI release 2020-05-28

object named as

Marisa Brini

6

0 references

7

object named as

Elena Zocchi

1 reference

Europe PubMed Central

11 August 2017

5

object named as

Laura Sturla

1 reference

Europe PubMed Central

11 August 2017

Santina Bruzzone

10

object named as

Santina Bruzzone

1 reference

Europe PubMed Central

11 August 2017

author name string

Mirko Magnone

1

1 reference

Europe PubMed Central

11 August 2017

Inga Bauer

2

1 reference

Europe PubMed Central

11 August 2017

Alessandro Poggi

3

1 reference

Europe PubMed Central

11 August 2017

Elena Mannino

4

1 reference

Europe PubMed Central

11 August 2017

Antonio De Flora

8

1 reference

Europe PubMed Central

11 August 2017

Alessio Nencioni

9

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

30 April 2012

1 reference

Europe PubMed Central

11 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

11 August 2017

287

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Europe PubMed Central

11 August 2017

25

1 reference

Europe PubMed Central

11 August 2017

21067-21081

1 reference

Europe PubMed Central

11 August 2017

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

1 reference

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The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism

1 reference

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2 October 2017

Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling

1 reference

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Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

TRPM2: a multifunctional ion channel for calcium signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

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Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival

1 reference

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A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis

1 reference

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The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer

1 reference

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Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

1 reference

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Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside.

1 reference

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The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

1 reference

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2 October 2017

TRPM2 functions as a lysosomal Ca2+-release channel in beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

The NMN/NaMN adenylyltransferase (NMNAT) protein family.

1 reference

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2 October 2017

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

1 reference

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2 October 2017

Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress

1 reference

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Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

1 reference

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2 October 2017

The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Calcium signaling in lymphocytes

1 reference

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2 October 2017

Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition

1 reference

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2 October 2017

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

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2 October 2017

Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Nicotinamide riboside kinase structures reveal new pathways to NAD+

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Calcium signalling in lymphocyte activation and disease

1 reference

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2 October 2017

Regulation of calcium signalling by adenine-based second messengers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

NAD+ metabolism in health and disease

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Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.

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Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum

1 reference

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2 October 2017

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells

1 reference

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Second messenger function and the structure-activity relationship of cyclic adenosine diphosphoribose (cADPR).

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2 October 2017

Quantitative real-time PCR for cancer detection: the lymphoma case

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2 October 2017

Store-operated calcium channels

1 reference

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2 October 2017

Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system

1 reference

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2 October 2017

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

1 reference

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Regulation of calcium signaling by the second messenger cyclic adenosine diphosphoribose (cADPR)

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2 October 2017

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2 October 2017

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

1 reference

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Mathematics of quantitative kinetic PCR and the application of standard curves

1 reference

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Calcium signalling: dynamics, homeostasis and remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

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WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells

1 reference

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Signatures of the immune response

1 reference

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2 October 2017

Immunocyte Ca2+ influx system mediated by LTRPC2.

1 reference

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2 October 2017

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

1 reference

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2 October 2017

Gene regulation mediated by calcium signals in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Calcium signaling mechanisms in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

2 October 2017

Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38.

1 reference

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Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity

1 reference

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Thapsigargin, a high affinity and global inhibitor of intracellular Ca2+ transport ATPases

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2 October 2017

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells

1 reference

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Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375530

11 July 2018

Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells

1 reference

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11 July 2018

Activation of T cell calcium influx by the second messenger ADP-ribose

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324269

21 January 2018

The calcium-signalling saga: tap water and protein crystals.

1 reference

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21 January 2018

Calcium-sensitive photoproteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324269

21 January 2018

Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324269

21 January 2018

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme activities leading to NAD synthesis in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the pyridine nucleotide synthesis pathway in mitogen-stimulated human T-lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.324269

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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