(Q36036700)

11 August 2017

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title

The genetics of human obesity. (English)

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11 August 2017

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3

Philippe Froguel

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Christopher G Bell

object named as

Christopher G Bell

series ordinal

1

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author name string

Andrew J Walley

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2

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11 August 2017

1 March 2005

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11 August 2017

Nature Reviews Genetics

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11 August 2017

6

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11 August 2017

3

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11 August 2017

221-234

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https://scigraph.springernature.com/pub.10.1038/nrg1556

11 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Genome-wide Linkage Analysis for Severe Obesity in French Caucasians Finds Significant Susceptibility Locus on Chromosome 19q

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Differentially expressed genes in visceral or subcutaneous adipose tissue of obese men and women

31 March 2020

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Gene expression profile of omental adipose tissue in human obesity

31 March 2020

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31 March 2020

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31 March 2020

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Genetic analysis of genome-wide variation in human gene expression

31 March 2020

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31 March 2020

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Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites

31 March 2020

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Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function

31 March 2020

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Genome-wide association studies for common diseases and complex traits

31 March 2020

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Genome-wide association studies: theoretical and practical concerns

31 March 2020

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Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

31 March 2020

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Advanced sequencing technologies: methods and goals

31 March 2020

1 reference

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

31 March 2020

1 reference

Glutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index.

31 March 2020

1 reference

Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians

31 March 2020

1 reference

Genomic variants in exons and introns: identifying the splicing spoilers

31 March 2020

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Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+)

31 March 2020

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Carbohydrate ingestion, blood glucose and mood

31 March 2020

1 reference

Regulation of appetite: role of leptin in signalling systems for drive and satiety

31 March 2020

1 reference

31 March 2020

1 reference

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome

31 March 2020

1 reference

Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes

31 March 2020

1 reference

Association of the human adiponectin gene and insulin resistance

31 March 2020

1 reference

DNA polymorphisms in the alpha 2- and beta 2-adrenoceptor genes and regional fat distribution in humans: association and linkage studies

31 March 2020

1 reference

Interactions among the α2-, β2-, and β3-adrenergic receptor genes and obesity-related phenotypes in the Quebec Family Study

31 March 2020

1 reference

The alpha 2-adrenergic receptor gene and body fat content and distribution: the HERITAGE Family Study.

31 March 2020

1 reference

Effect of a three-amino acid deletion in the α2B-adrenergic receptor gene on long-term body weight change in Finnish non-diabetic and type 2 diabetic subjects

31 March 2020

1 reference

Association between obesity and a polymorphism in the β1-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women

31 March 2020

1 reference

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function

31 March 2020

1 reference

Association of polymorphisms in the beta2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus

31 March 2020

1 reference

The Gln27Glu beta2-adrenergic receptor variant is associated with obesity due to subcutaneous fat accumulation in Japanese men

31 March 2020

1 reference

Impact of polymorphisms of the human β 2 -adrenoceptor gene on obesity in a French population

31 March 2020

1 reference

The Q/E27 polymorphism in the beta2-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins

31 March 2020

1 reference

Effects of beta2-adrenergic receptor gene variants on adiposity: the HERITAGE Family Study

31 March 2020

1 reference

Beta2 adrenoceptor functional gene variants, obesity, and blood pressure level interactions in the general population

31 March 2020

1 reference

Relationship between β-2 adrenoceptor gene haplotypes and adipocyte lipolysis in women

31 March 2020

1 reference

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

31 March 2020

1 reference

A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.

31 March 2020

1 reference

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

31 March 2020

1 reference

The Trp64Arg polymorphism of the β3-adrenergic receptor gene and obesity in Chinese subjects with components of the metabolic syndrome

31 March 2020

1 reference

Gender specific associations of the Trp64Arg mutation in the beta3-adrenergic receptor gene with obesity-related phenotypes in a Mediterranean population: interaction with a common lipoprotein lipase gene variation

31 March 2020

1 reference

beta(3) Adrenergic receptor polymorphism and obesity-related phenotypes in hypertensive patients

31 March 2020

1 reference

A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels

31 March 2020

1 reference

Novel polymorphisms in the 5' region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity

31 March 2020

1 reference

Sequence variants in the 5' flanking region of the leptin gene are associated with obesity in women

31 March 2020

1 reference

Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight

31 March 2020

1 reference

A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women

31 March 2020

1 reference

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil

31 March 2020

1 reference

LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women

31 March 2020

1 reference

Tests of linkage and/or association of the LEPR gene polymorphisms with obesity phenotypes in Caucasian nuclear families

31 March 2020

1 reference

Association of obesity, but not diabetes or hypertension, with glucocorticoid receptor N363S variant

31 March 2020

1 reference

The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus.

31 March 2020

1 reference

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

31 March 2020

1 reference

Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.

31 March 2020

1 reference

Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

31 March 2020

1 reference

Haplotype analysis of the PPARgamma Pro12Ala and C1431T variants reveals opposing associations with body weight.

31 March 2020

1 reference

The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study.

31 March 2020

1 reference

Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.

31 March 2020

1 reference

Effect of the peroxisome proliferator activated receptor-gamma gene Pro12Ala variant on body mass index: a meta-analysis

31 March 2020

1 reference

The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood

31 March 2020

1 reference

Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males

31 March 2020

1 reference

Peroxisome proliferator-activated receptor gamma gene locus is related to body mass index and lipid values in healthy nonobese subjects.

31 March 2020

1 reference

Association of -3826 G variant in uncoupling protein-1 with increased BMI in overweight Australian women.

31 March 2020

1 reference

Effects of uncoupling protein 1 and ß3-adrenergic receptor gene polymorphisms on body size and serum lipid concentrations in Japanese women

31 March 2020

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Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio.

31 March 2020

1 reference

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

31 March 2020

1 reference

An uncoupling protein 2 gene variant is associated with a raised body mass index but not Type II diabetes.

31 March 2020

1 reference

Frequency of and interaction between polymorphisms in the beta3-adrenergic receptor and in uncoupling proteins 1 and 2 and obesity in Germans

31 March 2020

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Associations between uncoupling protein 2, body composition, and resting energy expenditure in lean and obese African American, white, and Asian children

31 March 2020

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Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

31 March 2020

1 reference

Genetic variation in uncoupling protein 3 is associated with dietary intake and body composition in females

31 March 2020

1 reference

Uncoupling protein 3 gene is associated with body composition changes with training in HERITAGE study

31 March 2020

1 reference

Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population

31 March 2020

1 reference

A genetic variation in the 5' flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1556

1 reference

11 August 2017

1 reference

PubMed ID

15703762