(Q36037981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

mild cognitive impairment

23 January 2020

main subject

Alzheimer's disease

0 references

1 reference

based on heuristic

inferred from title

cognitive dysfunction

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Nobuto Kakuda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Hiroyuki Arai

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Katsutoshi Furukawa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Takeshi Ikeuchi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Kohei Akazawa

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Mako Takami

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Hiroyuki Hatsuta

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Shigeo Murayama

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Yasuhiro Hashimoto

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Masakazu Miyajima

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Hajime Arai

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Yu Nagashima

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Haruyasu Yamaguchi

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ryozo Kuwano

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Kazuhiro Nagaike

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Yasuo Ihara

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Japanese Alzheimer's Disease Neuroimaging Initiative

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

1 reference

21 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

published in

EMBO Molecular Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

344-352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Potent amyloidogenicity and pathogenicity of Aβ43.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Active gamma-secretase is localized to detergent-resistant membranes in human brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Amyloid beta1-40 quantification in CSF: comparison between chromatographic and immunochemical methods

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Alzheimer's disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: a hypothesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

The role of presenilin cofactors in the gamma-secretase complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Accumulation of amyloid beta-protein in the low-density membrane domain accurately reflects the extent of beta-amyloid deposition in the brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Alzheimer's disease: genes, proteins, and therapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376855

Neuropathological asymmetry in argyrophilic grain disease.

11 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

The beta APP717 Alzheimer mutation increases the percentage of plasma amyloid-beta protein ending at A beta42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

The validity of the family history method for identifying Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Biochemical markers in persons with preclinical familial Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Amyloid beta 38, 40, and 42 species in cerebrospinal fluid: more of the same?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Gamma-secretase activity is present in rafts but is not cholesterol-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEMMM.201200214

Angiotensin-converting enzyme converts amyloid beta-protein 1-42 (Abeta(1-42)) to Abeta(1-40), and its inhibition enhances brain Abeta deposition

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22354516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Guidelines for management of idiopathic normal pressure hydrocephalus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22354516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/EMMM.201200214

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22354516%20AND%20SRC:MED&resulttype=core&format=json