(Q36038664)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Kari Kopra

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Tero Aittokallio

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Daniel Abankwa

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Maja Šolman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Alessio Ligabue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Olga Blaževitš

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Alok Jaiswal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Yong Zhou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Hong Liang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Camilo Guzmán

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Harri Härmä

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

John F Hancock

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

14 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

e08905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4563131/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site

2 October 2017

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2 October 2017

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Drugging the undruggable RAS: Mission possible?

2 October 2017

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Small-molecule modulation of Ras signaling

2 October 2017

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2 October 2017

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The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering.

2 October 2017

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H-Ras forms dimers on membrane surfaces via a protein-protein interface.

2 October 2017

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Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

2 October 2017

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Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins

2 October 2017

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Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes

2 October 2017

1 reference

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A comprehensive survey of Ras mutations in cancer

2 October 2017

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Raf inhibitors target ras spatiotemporal dynamics

2 October 2017

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Nonsteroidal anti-inflammatory drugs alter the spatiotemporal organization of Ras proteins on the plasma membrane

2 October 2017

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Membrane mechanisms for signal transduction: the coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes

2 October 2017

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Revealing conformational substates of lipidated N-Ras protein by pressure modulation

2 October 2017

1 reference

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H-Ras nanocluster stability regulates the magnitude of MAPK signal output

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Ras membrane orientation and nanodomain localization generate isoform diversity

2 October 2017

1 reference

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A restricted spectrum of NRAS mutations causes Noonan syndrome

2 October 2017

1 reference

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Mechanisms of Ras membrane organization and signalling: Ras on a rocker.

2 October 2017

1 reference

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Mapping the nucleotide and isoform-dependent structural and dynamical features of Ras proteins

2 October 2017

1 reference

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Electrostatic interactions positively regulate K-Ras nanocluster formation and function

2 October 2017

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A novel switch region regulates H-ras membrane orientation and signal output

2 October 2017

1 reference

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Ras nanoclusters: molecular structure and assembly

2 October 2017

1 reference

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A FRET map of membrane anchors suggests distinct microdomains of heterotrimeric G proteins

2 October 2017

1 reference

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Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

2 October 2017

1 reference

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Hyperactive Ras in developmental disorders and cancer

2 October 2017

1 reference

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Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype

2 October 2017

1 reference

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H-ras, K-ras, and inner plasma membrane raft proteins operate in nanoclusters with differential dependence on the actin cytoskeleton

2 October 2017

1 reference

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A molecular timescale of eukaryote evolution and the rise of complex multicellular life

2 October 2017

1 reference

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Ras proteins: different signals from different locations

2 October 2017

1 reference

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Direct visualization of Ras proteins in spatially distinct cell surface microdomains

2 October 2017

1 reference

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Signaling pathways for PC12 cell differentiation: making the right connections

2 October 2017

1 reference

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Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

2 October 2017

1 reference

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The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

2 October 2017

1 reference

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

2 October 2017

1 reference

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Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Aggregation of lipid-anchored full-length H-Ras in lipid bilayers: simulations with the MARTINI force field

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

N-Ras forms dimers at POPC membranes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Observing cell surface signaling domains using electron microscopy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Nanoclusters of GPI-anchored proteins are formed by cortical actin-driven activity.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

Structure of a transient intermediate for GTP hydrolysis by ras.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563131

The role of G-domain orientation and nucleotide state on the Ras isoform-specific membrane interaction

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.08905

Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images

21 January 2018

1 reference

12 December 2020

A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction

1 reference

12 December 2020

Biochemical properties of Ha-ras encoded p21 mutants and mechanism of the autophosphorylation reaction

1 reference

12 December 2020

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.08905

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26274561%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26274561

1 reference