(Q36057369)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491935%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491935%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

1 reference

7

1 reference

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28 January 2020

author name string

Xiao-qin Zhao

1

1 reference

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28 January 2020

Jing-dun Xie

2

1 reference

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28 January 2020

Xing-gui Chen

3

1 reference

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28 January 2020

Hong May Sim

4

1 reference

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28 January 2020

Xu Zhang

5

1 reference

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28 January 2020

Yong-ju Liang

6

1 reference

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28 January 2020

Tanaji T Talele

8

1 reference

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28 January 2020

Yueli Sun

9

1 reference

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28 January 2020

Suresh V Ambudkar

10

1 reference

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28 January 2020

Zhe-Sheng Chen

11

1 reference

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28 January 2020

Li-wu Fu

12

1 reference

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28 January 2020

publication date

4 April 2012

1 reference

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28 January 2020

published in

Molecular Pharmacology

1 reference

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28 January 2020

volume

82

1 reference

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28 January 2020

issue

1

1 reference

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28 January 2020

page(s)

47-58

1 reference

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describes a project that uses

28 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3382829/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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A genome-wide RNAi screen identifies novel targets of neratinib sensitivity leading to neratinib and paclitaxel combination drug treatments.

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Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.

2 October 2017

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Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects

2 October 2017

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Impact of ABCB1 allelic variants on QTc interval prolongation

2 October 2017

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Present and future evolution of advanced breast cancer therapy

2 October 2017

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Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer

2 October 2017

1 reference

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Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function

2 October 2017

1 reference

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Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance

2 October 2017

1 reference

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Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

2 October 2017

1 reference

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Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2.

2 October 2017

1 reference

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Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage

2 October 2017

1 reference

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

2 October 2017

1 reference

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Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein

2 October 2017

1 reference

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HKI-272 in non small cell lung cancer.

2 October 2017

1 reference

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Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.

2 October 2017

1 reference

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Targeting multidrug resistance in cancer

2 October 2017

1 reference

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ERK activation by thymosin-beta-4 (TB4) overexpression induces paclitaxel-resistance

2 October 2017

1 reference

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Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers

2 October 2017

1 reference

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Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo

2 October 2017

1 reference

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Optimization of 6,7-disubstituted-4-(arylamino)quinoline-3-carbonitriles as orally active, irreversible inhibitors of human epidermal growth factor receptor-2 kinase activity.

2 October 2017

1 reference

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Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318.

2 October 2017

1 reference

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Antitumor activity of HKI-272, an orally active, irreversible inhibitor of the HER-2 tyrosine kinase

2 October 2017

1 reference

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Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Multidrug resistance in cancer: role of ATP-dependent transporters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2 October 2017

1 reference

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The human ATP-binding cassette (ABC) transporter superfamily

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Screening novel, potent multidrug-resistant modulators from imidazole derivatives

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

FDA drug approval summary: gefitinib (ZD1839) (Iressa) tablets

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Reversible Covalent Binding of Neratinib to Human Serum Albumin In Vitro

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor: results of a phase II trial in patients with advanced non-small-cell lung cancer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

A phase I study with neratinib (HKI-272), an irreversible pan ErbB receptor tyrosine kinase inhibitor, in patients with solid tumors

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

FDA drug approval summary: erlotinib (Tarceva) tablets

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

Characterization of tetrandrine, a potent inhibitor of P-glycoprotein-mediated multidrug resistance

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382829

23 September 2018

Identifiers

DOI

10.1124/MOL.111.076299

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491935%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491935%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

22491935

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491935%20AND%20SRC:MED&resulttype=core&format=json