(Q36078222)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Neil Box

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

7

D R Roop

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

E C Torchia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

C Caulin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

T Terzian

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

B J Kubick

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

3 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

2680-2690

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2011.441

13 February 2020

exact match

0 references

cites work

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2 October 2017

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Suppression of Aurora-A oncogenic potential by c-Myc downregulation

2 October 2017

1 reference

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Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.

2 October 2017

1 reference

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2 October 2017

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2 October 2017

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Biology of Aurora A kinase: implications in cancer manifestation and therapy

2 October 2017

1 reference

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Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells

2 October 2017

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Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells

2 October 2017

1 reference

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Mutant p53 drives invasion by promoting integrin recycling

2 October 2017

1 reference

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Pharmacological activation of the p53 pathway in haematological malignancies

2 October 2017

1 reference

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Small molecule inhibitors of Myc/Max dimerization and Myc-induced cell transformation

2 October 2017

1 reference

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A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors

2 October 2017

1 reference

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When mutants gain new powers: news from the mutant p53 field.

2 October 2017

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2 October 2017

Cancer statistics, 2009

1 reference

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Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice

2 October 2017

1 reference

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The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

2 October 2017

1 reference

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Rho GTPase function in tumorigenesis

2 October 2017

1 reference

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A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53

2 October 2017

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

2 October 2017

1 reference

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Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases

2 October 2017

1 reference

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The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

2 October 2017

1 reference

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Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

2 October 2017

1 reference

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An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations

2 October 2017

1 reference

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GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases

2 October 2017

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The ever expanding role for c-Myc in promoting genomic instability

2 October 2017

1 reference

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Aurora-A kinase interacting protein 1 (AURKAIP1) promotes Aurora-A degradation through an alternative ubiquitin-independent pathway

2 October 2017

1 reference

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The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology.

2 October 2017

1 reference

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Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells

2 October 2017

1 reference

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Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma

2 October 2017

1 reference

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Centrosome amplification, chromosome instability and cancer development

2 October 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

2 October 2017

1 reference

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Non-melanoma skin cancer: what drives tumor development and progression?

2 October 2017

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

2 October 2017

1 reference

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The p53 pathway: positive and negative feedback loops

2 October 2017

1 reference

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Chfr is required for tumor suppression and Aurora A regulation

2 October 2017

1 reference

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The role of UV induced lesions in skin carcinogenesis: an overview of oncogene and tumor suppressor gene modifications in xeroderma pigmentosum skin tumors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Expression profiling of epithelial plasticity in tumor progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

DAVID: Database for Annotation, Visualization, and Integrated Discovery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Skin cancers after organ transplantation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

High metastatic potential in mice inheriting a targeted p53 missense mutation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

2 October 2017

The Hallmarks of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Molecular changes in oral cancer may reflect aetiology and ethnic origin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

More powerful procedures for multiple significance testing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Ras gene mutation and amplification in human nonmelanoma skin cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

c-myc oncogene copy number in squamous carcinoma of the head and neck.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

The ultraviolet fingerprint dominates the mutational spectrum of the p53 and Ha-ras genes in psoralen + ultraviolet A keratoses from psoriasis patients.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

High frequency of ultraviolet mutations at the INK4a-ARF locus in squamous cell carcinomas from psoralen-plus-ultraviolet-A-treated psoriasis patients

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Myc lacks E2F1's ability to suppress skin carcinogenesis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4576849

Genomic aberrations in squamous cell lung carcinoma related to lymph node or distant metastasis

23 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Investigation of c-myc oncogene amplification in colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Activated ras genes occur in human actinic keratoses, premalignant precursors to squamous cell carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Investigation of c-myc and p53 gene alterations in the tumor and surgical borderline tissues of NSCLC and effects on clinicopathologic behavior: by the FISH technique

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

A genetic mouse model for metastatic lung cancer with gender differences in survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.441

Fish detected p53 deletion and N-MYC amplification in colorectal cancer

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21963848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2011.441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21963848%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference