(Q36082984)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26396593%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery (English)

1 reference

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24 February 2020

1 reference

16

1 reference

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24 February 2020

Michelle Craig Barton

17

1 reference

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24 February 2020

Jannik N Andersen

21

1 reference

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24 February 2020

14

Carlo Toniatti

1 reference

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24 February 2020

15

Giulio Draetta

1 reference

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24 February 2020

author name string

Yanai Zhan

1

1 reference

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24 February 2020

Maria Kost-Alimova

2

1 reference

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24 February 2020

Xi Shi

3

1 reference

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24 February 2020

Elisabetta Leo

4

1 reference

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24 February 2020

Jennifer P Bardenhagen

5

1 reference

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24 February 2020

Hannah E Shepard

6

1 reference

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24 February 2020

Srikanth Appikonda

7

1 reference

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24 February 2020

Bhavatarini Vangamudi

8

1 reference

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24 February 2020

Shuping Zhao

9

1 reference

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24 February 2020

Trang N Tieu

10

1 reference

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24 February 2020

Shiming Jiang

11

1 reference

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24 February 2020

Timothy P Heffernan

12

1 reference

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24 February 2020

Joseph R Marszalek

13

1 reference

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24 February 2020

Philip Jones

18

1 reference

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24 February 2020

Wylie S Palmer

19

1 reference

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24 February 2020

Mary K Geck Do

20

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24 February 2020

publication date

21 September 2015

1 reference

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24 February 2020

published in

Epigenetics & Chromatin

1 reference

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24 February 2020

volume

8

1 reference

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24 February 2020

page(s)

37

1 reference

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https://scigraph.springernature.com/pub.10.1186/s13072-015-0026-4

24 February 2020

exact match

0 references

cites work

The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

1 reference

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Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

2 October 2017

1 reference

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NanoBRET--A Novel BRET Platform for the Analysis of Protein-Protein Interactions

2 October 2017

1 reference

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Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Protein-protein interaction modulator drug discovery: past efforts and future opportunities using a rich source of low- and high-throughput screening assays

2 October 2017

1 reference

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Unravelling the genomic targets of small molecules using high-throughput sequencing

2 October 2017

1 reference

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Cell-based protein stabilization assays for the detection of interactions between small-molecule inhibitors and BRD4.

2 October 2017

1 reference

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Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

2 October 2017

1 reference

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Readers of histone methylarginine marks.

2 October 2017

1 reference

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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers

2 October 2017

1 reference

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Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation

2 October 2017

1 reference

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RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist

2 October 2017

1 reference

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Genome-wide localization of small molecules

2 October 2017

1 reference

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BET bromodomain inhibitors: a patent review

2 October 2017

1 reference

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RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

2 October 2017

1 reference

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Development of multiple cell-based assays for the detection of histone H3 Lys27 trimethylation (H3K27me3).

2 October 2017

1 reference

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A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

2 October 2017

1 reference

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Malignant genome reprogramming by ATAD2.

2 October 2017

1 reference

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H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins

2 October 2017

1 reference

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Epigenetic protein families: a new frontier for drug discovery

2 October 2017

1 reference

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Histone recognition and large-scale structural analysis of the human bromodomain family

2 October 2017

1 reference

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Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)

2 October 2017

1 reference

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From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Histone deacetylase inhibitors globally enhance h3/h4 tail acetylation without affecting h3 lysine 56 acetylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

TRIM24 links a non-canonical histone signature to breast cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Selective inhibition of BET bromodomains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

In situ subcellular fractionation of adherent and non-adherent mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Fluorescence-based methods in the study of protein-protein interactions in living cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

High-resolution profiling of histone methylations in the human genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Direct observation of individual endogenous protein complexes in situ by proximity ligation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

A small molecule-kinase interaction map for clinical kinase inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Translating the Histone Code

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Chromatin binding of the fission yeast replication factor mcm4 occurs during anaphase and requires ORC and cdc18.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

In situ assay for analyzing the chromatin binding of proteins in fission yeast.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4578755

10.1186/S13072-015-0026-4

23 September 2018

Identifiers

DOI

1 reference

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Dimensions Publication ID

24 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26396593%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26396593

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26396593%20AND%20SRC:MED&resulttype=core&format=json