(Q36089054)

12 August 2017

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title

Wnt signalling and prostate cancer (English)

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12 August 2017

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Yardy GW

1

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12 August 2017

Brewster SF

series ordinal

2

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12 August 2017

publication date

1 January 2005

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Prostate Cancer and Prostatic Diseases

12 August 2017

published in

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12 August 2017

volume

8

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12 August 2017

issue

2

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12 August 2017

page(s)

119-126

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Mechanisms of Wnt signaling in development

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

A frizzled homolog functions in a vertebrate Wnt signaling pathway

21 January 2018

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dishevelled and armadillo act in the wingless signalling pathway in Drosophila

21 January 2018

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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

21 January 2018

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

21 January 2018

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Localization of the gene for familial adenomatous polyposis on chromosome 5.

21 January 2018

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GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Beta-catenin signaling in prostate cancer: an early perspective

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

21 January 2018

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The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Nuclear translocation of beta-catenin in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Beta-catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

21 January 2018

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Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Crossregulation of NF-kappaB by the APC/GSK-3beta/beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Activation of the beta-catenin/Lef-Tcf pathway is obligate for formation of primitive endoderm by mouse F9 totipotent teratocarcinoma cells in response to retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Identification of Tcf-4 as a transcriptional target of p53 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Downregulation of beta-catenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Cyclin-dependent kinase 2 regulates the interaction of Axin with beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Beta-catenin mutations in cell lines established from human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear beta-catenin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

AXIN1 mutations but not deletions in cerebellar medulloblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Regulation of angiogenesis by glycogen synthase kinase-3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

State of adenomatous polyposis coli gene and ras oncogenes in Japanese prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

E-cadherin and beta-catenin are down-regulated in prostatic bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Expression, structure, and function of androgen receptor in advanced prostatic carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Linking beta-catenin to androgen-signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Ligand-dependent inhibition of beta-catenin/TCF signaling by androgen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Expression of androgen receptor coregulators in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Folic acid reduces nuclear translocation of beta-catenin in rectal mucosal crypts of patients with colorectal adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal antiinflammatory drugs (NSAIDs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate beta-catenin/TCF-4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

SMAF-1 inhibits the APC/beta-catenin pathway and shows properties similar to those of the tumor suppressor protein APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The suppression of colon cancer cell growth in nude mice by targeting beta-catenin/TCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Ceramide regulates lipopolysaccharide-induced phosphatidylinositol 3-kinase and Akt activity in human alveolar macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Familial multiple polyposis.A statistical study of a large kentucky kindred

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

APC gene mutations in human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Detection and analysis of beta-catenin mutations in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Micronutrients and cancer risk

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https://api.crossref.org/works/10.1038%2FSJ.PCAN.4500794

7 January 2021

Identifiers

DOI

10.1038/SJ.PCAN.4500794

1 reference

12 August 2017

1 reference