(Q36089361)

12 August 2017

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title

Invertebrate models of Alzheimer's disease. (English)

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12 August 2017

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Link CD

1

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12 August 2017

language of work or name

English

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publication date

1 April 2005

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Genes, Brain and Behavior

12 August 2017

published in

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12 August 2017

volume

4

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12 August 2017

issue

3

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12 August 2017

page(s)

147-156

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Inclusion-body myositis: newest concepts of pathogenesis and relation to aging and Alzheimer disease

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

AlphaB-crystallin immunolocalization yields new insights into inclusion body myositis.

21 January 2018

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Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Neuropathological stageing of Alzheimer-related changes

21 January 2018

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

21 January 2018

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What the evolution of the amyloid protein precursor supergene family tells us about its function

21 January 2018

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium

21 January 2018

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Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model

21 January 2018

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Dying for a cause: invertebrate genetics takes on human neurodegeneration

21 January 2018

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Screening for presenilin inhibitors using the free-living nematode, Caenorhabditis elegans

21 January 2018

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A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

21 January 2018

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Interaction of intracellular beta amyloid peptide with chaperone proteins

21 January 2018

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aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

21 January 2018

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Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease

21 January 2018

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Intraneuronal Abeta42 accumulation in human brain.

21 January 2018

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APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

21 January 2018

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Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.

21 January 2018

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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

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Altered microtubule organization in small-calibre axons of mice lacking tau protein

21 January 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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Identification and characterization of the Drosophila tau homolog.

21 January 2018

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

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Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

21 January 2018

1 reference

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The gamma-secretase complex: machinery for intramembrane proteolysis

21 January 2018

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

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Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP

21 January 2018

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Genome-wide RNAi screening in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

21 January 2018

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Direct observation of stress response in Caenorhabditis elegans using a reporter transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

ptl-1, a Caenorhabditis elegans gene whose products are homologous to the tau microtubule-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Tau is a candidate gene for chromosome 17 frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Tau and tau reporters disrupt central projections of sensory neurons in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2004.00105.X

10.1111/J.1601-183X.2004.00105.X

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference