(Q36099627)

English

Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Unique structure and regulation of the nematode detoxification gene regulator, SKN-1: implications to understanding and controlling drug resistance (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Keith P Choe

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Chi K Leung

2

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Europe PubMed Central

PMC publication ID

12 August 2017

Michael M Miyamoto

3

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Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

4 June 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

Drug Metabolism Reviews

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Europe PubMed Central

PMC publication ID

12 August 2017

44

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

209-223

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1.

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Drug resistance in yeasts--an emerging scenario

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Anthelmintic resistance in human helminths: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Glutathione-S-transferase family of enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Drug resistance in human helminths: current situation and lessons from livestock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

The SKN-1 amino-terminal arm is a DNA specificity segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Cancer multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

A new DNA-binding motif in the Skn-1 binding domain-DNA complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

A molecular evolutionary framework for the phylum Nematoda

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

SKN-1 domain folding and basic region monomer stabilization upon DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Skn-1: evidence for a bipartite recognition helix in DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Glutathione and related enzymes in multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Anthelmintic resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 October 2017

Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

Activation of SKN-1 by novel kinases in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

An investigation of persistent microfilaridermias despite multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

A C. elegans orphan nuclear receptor contributes to xenobiotic resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

Avermectin B1 toxicity in a herd of Murray Grey cattle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3398467

2 July 2018

Inventory and analysis of ATP-binding cassette (ABC) systems in Brugia malayi

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Evolution of the beta-propeller fold.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

The New View of Animal Phylogeny

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Acrylamide-responsive genes in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

The nematode Pristionchus pacificus (Nematoda: Diplogastridae) is associated with the oriental beetle Exomala orientalis (Coleoptera: Scarabaeidae) in Japan

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

The Global Programme to Eliminate Lymphatic Filariasis: health impact during its first 8 years (2000-2007).

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

The AHR-1 aryl hydrocarbon receptor and its co-factor the AHA-1 aryl hydrocarbon receptor nuclear translocator specify GABAergic neuron cell fate in C. elegans.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Phylogeny, taxonomy, and evolution of the endothelin receptor gene family

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Characterization of the xenobiotic response of Caenorhabditis elegans to the anthelmintic drug albendazole and the identification of novel drug glucoside metabolites.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus).

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Drug discovery: fresh hope to can the worms

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

MDR1-deficient genotype in Collie dogs hypersensitive to the P-glycoprotein substrate ivermectin

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Thioredoxins of a parasitic nematode: comparison of the 16- and 12-kDA thioredoxins from Haemonchus contortus

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer.

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Assembling the spiralian tree of life

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.684799

21 January 2018

Glutathione and glutathione-dependent enzymes in cancer drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caenorhabditis elegans Is a Nematode

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oesophagostomum dentatum: Effect of glutathione S-transferase (GST) inhibitors on GST activity and larval development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin D2 synthesis in Oesophagostomum dentatum is mediated by cytosolic Glutathione S-transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione-S-transferase, a possible drug-metabolizing enzyme, in Haemonchus contortus: comparative activity of a cambendazole-resistant and a susceptible strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/22656429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3109/03602532.2012.684799

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

Sitelinks

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