(Q36102590)

English

Limited influence of UGT1A128 and no effect of UGT2B72 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes

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Europe PubMed Central

PMC publication ID

12 August 2017

Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Vincent C Peterkin

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jonathan N Bauman

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Theunis C Goosen

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Lee Menning

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Michael Z Man

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Joseph D Paulauskis

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

J Andrew Williams

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Scott P Myrand

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

6 June 2007

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

64

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

458-468

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

So many studies, too few subjects: establishing functional relevance of genetic polymorphisms on pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

UDP-glucuronosyltransferases and clinical drug-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 October 2017

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

2 July 2018

Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

Correlation between the UDP-glucuronosyltransferase (UGT1A1) TATAA box polymorphism and carcinogen detoxification phenotype: significantly decreased glucuronidating activity against benzo(a)pyrene-7,8-dihydrodiol(-) in liver microsomes from subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048551

23 September 2018

UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE NOVEL UGT1A9 INTRONIC I399 POLYMORPHISM APPEARS AS A PREDICTOR OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN GLUCURONIDATION LEVELS IN THE LIVER

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y), and UGT2B15(D85Y)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human variability in glucuronidation in relation to uncertainty factors for risk assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UDP glucuronosyltransferase mRNA levels in human liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17555467

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2007.02923.X

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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