(Q45001560)

8 December 2017

Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38. (English)

1 reference

8 December 2017

Luca Paoluzzi

1

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Alex Sparreboom

8

object named as

Alex Sparreboom

1 reference

8 December 2017

6

Jaap Verweij

1 reference

8 December 2017

Arun S Singh

2

1 reference

8 December 2017

Douglas K Price

3

1 reference

8 December 2017

Romano Danesi

4

1 reference

8 December 2017

Ron H J Mathijssen

5

1 reference

8 December 2017

William D Figg

7

1 reference

8 December 2017

1 August 2004

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The Journal of Clinical Pharmacology

8 December 2017

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8 December 2017

44

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8 December 2017

8

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8 December 2017

854-860

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Human UDP-glucuronosyltransferases: metabolism, expression, and disease

8 December 2017

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Vertebrate UDP-glucuronosyltransferases: functional and evolutionary aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Differential and Special Properties of the Major Human UGT1-encoded Gastrointestinal UDP-glucuronosyltransferases Enhance Potential to Control Chemical Uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

UDP-glucuronosyltransferase activity in human liver and colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Clinical pharmacokinetics of irinotecan and its metabolites: a population analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Pharmacokinetic and pharmacodynamic evaluation of the topoisomerase inhibitor irinotecan in cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9*22) and its effects on the transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270004267159

21 January 2018

Identifiers

DOI

10.1177/0091270004267159

1 reference

8 December 2017

1 reference