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Human variability in glucuronidation in relation to uncertainty factors for risk assessment
scientific article published on 01 December 2001
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1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
title
Human variability in glucuronidation in relation to uncertainty factors for risk assessment
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
author name string
J L Dorne
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
K Walton
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
A G Renwick
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
publication date
1 December 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
published in
Food and Chemical Toxicology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
volume
39
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
page(s)
1153-1173
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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1 reference
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Determinants of acetaminophen metabolism: effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways
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Paracetamol metabolism in pregnancy
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7 January 2021
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Comparison of paracetamol metabolism in young adult and elderly males
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7 January 2021
based on heuristic
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Drug glucuronidation in humans
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7 January 2021
based on heuristic
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Cimetidine does not alter morphine disposition in man.
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7 January 2021
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based on heuristic
inferred from DOI database lookup
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based on heuristic
inferred from DOI database lookup
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https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative bioavailability and pharmacokinetics of chloramphenicol after intravenous chloramphenicol succinate in premature infants and older patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation in morphine pharmacokinetics in children with cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetic study of chloramphenicol in patients with liver disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Zomepirac kinetics in healthy males
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics and bioavailability of intravenous and intramuscular lorazepam with an adjunct test of the inattention effect in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disposition of zomepirac sodium in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pharmacokinetics of morphine and morphine glucuronides in kidney failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pharmacokinetics of lamotrigine (BW430C) in healthy subjects with unconjugated hyperbilirubinaemia (Gilbert's syndrome).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paracetamol disposition and metabolite kinetics in patients with chronic renal failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Method for the Determination of UDP-Glucuronosyltransferase Activity toward Arylcarboxylic Acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional studies of UDP-glucuronosyltransferases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of intravenous atropine on gastric emptying, paracetamol absorption, salivary flow and heart rate in young and fit elderly volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics of paracetamol (acetaminophen) after intravenous and oral administration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pharmacokinetics and metabolism of 14C-carprofen in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics of Carprofen in Plasma and Synovial Fluid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lorazepam pharmacodynamics and pharmacokinetics in children.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Data-derived safety factors for the evaluation of food additives and environmental contaminants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human variability and noncancer risk assessment- An analysis of the default uncertainty factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stereoselective pharmacokinetics and inversion of (R)- ketoprofen in healthy volunteers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of posture and sleep on the pharmacokinetics of paracetamol (acetaminophen) and its metabolites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions and comparative effects of zopiclone, diazepam and lorazepam on psychomotor performance and on elimination pharmacokinetics in healthy volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drugs and phenols glucuronidation in Caco-2 cells: identification of the UDP-glucuronosyltransferases UGT1A6, 1A3 and 2B7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of morphine in patients with renal failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxazepam pharmacokinetics in patients with epilepsy treated long-term with phenytoin alone or in combination with phenobarbitone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on morphine disposition: influence of general anaesthesia on plasma concentrations of morphine and its metabolites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies on morphine disposition: influence of renal failure on the kinetics of morphine and its metabolites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative pharmacokinetics of zidovudine (AZT) and its metabolite (G.AZT) in healthy subjects and HIV seropositive patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bioavailability and pharmacokinetics of oxazepam
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Racial differences in propranolol enantiomer kinetics following simultaneous i.v. and oral administration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical pharmacokinetics of 3'-azido-3'-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3'-amino-3'-deoxythymidine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of effect of paracetamol on the pharmacokinetics of chloramphenicol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics of zidovudine in patients with liver cirrhosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolism of thiamphenicol and comparative studies of its urinary and biliary excretion with chloramphenicol in various species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of diflunisal on the pharmacokinetics of oxazepam
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetics of intravenous morphine in balanced anesthesia: studies in children.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of concurrent antiepileptic medication on the pharmacokinetics of lamotrigine as add-on therapy in epileptic children
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of multiple dosage on the kinetics of glucuronidation and sulphation of diflunisal in man.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial metabolic clearances as determinants of the oral bioavailability of propranolol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulatory as well as inhibitory effects of ethinyloestradiol on the metabolic clearances of propranolol in young women
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uncertainty factors for chemical risk assessment: interspecies differences in glucuronidation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Morphine pharmacokinetics and effects on salivation and continuous reaction times in healthy volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal glucuronidation of zomepirac in patients with cirrhosis of the liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of renal function on the elimination of morphine and morphine glucuronides.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pharmacokinetics of single oral doses of zileuton 200 to 800mg, its enantiomers, and its metabolites, in normal healthy volunteers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renal failure does not impair the metabolism of morphine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The association of age and frailty with paracetamol conjugation in man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interindividual and interethnic differences in the demethylation and glucuronidation of codeine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative pharmacokinetics of zidovudine and its toxic catabolite 3'-amino-3'-deoxythymidine in HIV-infected patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-6915%2801%2900087-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0278-6915(01)00087-4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
PubMed publication ID
11696390
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11696390
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11696390%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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