(Q36124536)

12 August 2017

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title

Views from within and beyond: narratives of cardiac contractile dysfunction under senescence (English)

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12 August 2017

Xiaoping Yang

1

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12 August 2017

Nair Sreejayan

series ordinal

2

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12 August 2017

Jun Ren

series ordinal

3

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12 August 2017

language of work or name

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1 March 2005

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12 August 2017

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12 August 2017

volume

26

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12 August 2017

issue

2

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12 August 2017

page(s)

127-137

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Age-dependent expression of fibrosis-related genes and collagen deposition in the rat myocardium1This study was presented in part at the 49th Annual Meeting of the `Gerontological Society of America', Washington, November 17–21, 1996.1

12 August 2017

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Advanced glycation end product cross-linking: pathophysiologic role and therapeutic target in cardiovascular disease

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Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes.

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The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

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12 December 2020

What do hormones have to do with aging? What does aging have to do with hormones?

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12 December 2020

Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress

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Is Akt the mastermind behind age-related heart disease?

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12 December 2020

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

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12 December 2020

Aging: a theory based on free radical and radiation chemistry

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12 December 2020

Cardiovascular aging research: the next horizons

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12 December 2020

Inflammatory markers and incident mobility limitation in the elderly

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12 December 2020

Ageing, hormones, body composition, metabolic effects

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12 December 2020

Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys

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12 December 2020

Does exceptional human longevity come with a high cost of infertility? Testing the evolutionary theories of aging

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12 December 2020

When cells get stressed: an integrative view of cellular senescence

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12 December 2020

Age-associated changes in beta-adrenergic modulation on rat cardiac excitation-contraction coupling

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12 December 2020

Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse.

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12 December 2020

Androgens and cardiovascular disease

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12 December 2020

Ca2+ transients of cardiomyocytes from senescent mice peak late and decay slowly

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12 December 2020

Impact of age on the cardiovascular response to dynamic upright exercise in healthy men and women.

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12 December 2020

Human longevity at the cost of reproductive success

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12 December 2020

Phytoestrogenic isoflavones daidzein and genistein reduce glucose-toxicity-induced cardiac contractile dysfunction in ventricular myocytes

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12 December 2020

Growth hormone treatment increases circulating lipoprotein(a) in children with chronic renal failure

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12 December 2020

The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter

1 reference

12 December 2020

Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats

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12 December 2020

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

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12 December 2020

Treatment With Growth Hormone Enhances Contractile Reserve and Intracellular Calcium Transients in Myocytes From Rats With Postinfarction Heart Failure

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12 December 2020

Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with IGF-I deficiency

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12 December 2020

Age-dependent changes in myosin composition correlate with enhanced economy of contraction in guinea-pig hearts

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12 December 2020

Therapeutic potential of breakers of advanced glycation end product–protein crosslinks

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12 December 2020

The genetics of aging

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12 December 2020

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

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12 December 2020

Reduced threshold for myocardial cell calcium intolerance in the rat heart with aging

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12 December 2020

Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy

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12 December 2020

Ageing of the hypothalamo-pituitary-testicular axis in men.

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12 December 2020

Echocardiographic dimensions and function in adults with primary growth hormone resistance (Laron syndrome).

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12 December 2020

Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function

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12 December 2020

Growth hormone prolongs survival in experimental postinfarction heart failure

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12 December 2020

IGF-I attenuates diabetes-induced cardiac contractile dysfunction in ventricular myocytes

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12 December 2020

Influence of gender on intrinsic contractile properties of isolated ventricular myocytes from calmodulin-induced diabetic transgenic mice

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12 December 2020

Contractile response of individual cardiac myocytes to norepinephrine declines with senescence

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12 December 2020

Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents

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12 December 2020

Living and dying for sex. A theory of aging based on the modulation of cell cycle signaling by reproductive hormones

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12 December 2020

Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men

1 reference

12 December 2020

Effect of oral estradiol on Lp(a) and other lipoproteins in postmenopausal women. A randomized, double-blind, placebo-controlled, crossover study

1 reference

12 December 2020

The influence of aging on the human sympathetic nervous system and brain norepinephrine turnover

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12 December 2020

Age-associated changes in left ventricular diastolic performance during isometric exercise in normal subjects

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12 December 2020

Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart

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12 December 2020

Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats.

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12 December 2020

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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12 December 2020

Improved arterial compliance by a novel advanced glycation end-product crosslink breaker

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12 December 2020

Use of growth hormone for prevention or treatment of effects of aging

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12 December 2020

Gender differences and aging: effects on the human heart

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12 December 2020

Oxidants, oxidative stress and the biology of ageing

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12 December 2020

The biochemistry of aging

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12 December 2020

Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study

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12 December 2020

Menopause and the Aging Female Reproductive System

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12 December 2020

Polymorphisms in androgen and estrogen receptor genes: effects on male aging

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12 December 2020

Decrease with senescence in the norepinephrine-induced phosphorylation of myofilament proteins in isolated rat cardiac myocytes

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12 December 2020

A Preliminary Study of Growth Hormone in the Treatment of Dilated Cardiomyopathy

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12 December 2020

Cardiomyocyte aging is gender-dependent: the local IGF-1-IGF-1R system

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12 December 2020

A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.

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12 December 2020

Congestive heart failure in the community: a study of all incident cases in Olmsted County, Minnesota, in 1991.

1 reference

12 December 2020

Increasing longevity by decreasing sympathetic stress--early beta receptor blockade pharmacotherapy

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12 December 2020

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation

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12 December 2020

Aging: is oxidative stress a marker or is it causal?

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12 December 2020

Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men.

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12 December 2020

Postural changes in cardiac volumes in men in relation to adult age

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12 December 2020

Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population

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12 December 2020

Ras: the other pro-aging pathway

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12 December 2020

High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts

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12 December 2020

17beta-estradiol attenuates the development of pressure-overload hypertrophy

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12 December 2020

Do deficiencies in growth hormone and insulin-like growth factor-1 (IGF-1) shorten or prolong longevity?

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12 December 2020

Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

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12 December 2020

Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction

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12 December 2020

Multiple system atrophy

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12 December 2020

Action potential prolongation in cardiac myocytes of old rats is an adaptation to sustain youthful intracellular Ca2+ regulation.

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12 December 2020

Cardiac stem cells fail with aging: a new mechanism for the age-dependent decline in cardiac function

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12 December 2020

An examination of the effect of combined cyclical hormone replacement therapy on lipoprotein(a) and other lipoproteins

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12 December 2020

Age-dependent expression of advanced glycation end product receptor genes in the human heart

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12 December 2020

Diabetes and advanced glycation endproducts

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12 December 2020

Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R.

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12 December 2020

Loss of cardiac contractile response to tetrahydropapaveroline with advanced age and hypertension.

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12 December 2020

Diabetes, lipids, and adipocyte secretagogues

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12 December 2020

Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus

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12 December 2020

Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification

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12 December 2020

ARF Tumor Suppressor Induces Mitochondria-dependent Apoptosis by Modulation of Mitochondrial Bcl-2 Family Proteins

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12 December 2020

Mitochondrial DNA and aging

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12 December 2020

Effects of aging on the cardiac remodeling induced by chronic high-altitude hypoxia in rat.

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12 December 2020

The biology of the receptor for advanced glycation end products and its ligands

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12 December 2020

Effects of insulin-like growth factor-I deficiency and replacement therapy on the hematopoietic system in patients with Laron syndrome (primary growth hormone insensitivity).

1 reference

12 December 2020

The role of glycation in aging and diabetes mellitus

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12 December 2020

Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel

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12 December 2020

Diastolic dysfunction and the aging heart

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12 December 2020

p66ShcA modulates tissue response to hindlimb ischemia.

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12 December 2020

Aminoguanidine prevents age-related deterioration in left ventricular-arterial coupling in Fisher 344 rats

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12 December 2020

Inflammatory markers and physical performance in older persons: the InCHIANTI study

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12 December 2020

Cardiac mass and function, carotid artery intima-media thickness, and lipoprotein levels in growth hormone-deficient adolescents

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12 December 2020

The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo

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12 December 2020

Aging effects on human sympathetic neuronal function

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12 December 2020

A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys

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12 December 2020

Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors.

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12 December 2020

IGF-1 and insulin as growth hormones.

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12 December 2020

TRF2 Protects Human Telomeres from End-to-End Fusions

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12 December 2020

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

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12 December 2020

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

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12 December 2020

Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction

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12 December 2020

A glucosylceramide with a novel ceramide and three novel ceramides from the basidiomycete Cortinarius umidicola

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12 December 2020

Effect of insulin treatment on serum lipoprotein(a) in non-insulin-dependent diabetes

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12 December 2020

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

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12 December 2020

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12 December 2020

Role of calcium in adrenergic neurochemical transmission in the aging heart

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12 December 2020

Signal transduction pathways in mouse microglia N-11 cells activated by advanced glycation endproducts (AGEs).

1 reference

12 December 2020

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

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12 December 2020

Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products

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12 December 2020

Impact of gender on basal and insulin-like growth factor I-regulated nitric oxide synthase activity in adult rat left ventricular myocytes

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12 December 2020

Oxidative stress in cardiovascular disease: myth or fact?

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12 December 2020

The endocrine regulation of aging by insulin-like signals

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12 December 2020

Insulin-like growth factors (IGFs) and IGF-binding proteins in nephrotic syndrome children on glucocorticoid

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12 December 2020

Dwarf mice and the ageing process.

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12 December 2020

Impact of estrogen replacement on ventricular myocyte contractile function and protein kinase B/Akt activation

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12 December 2020

Extension of life-span by introduction of telomerase into normal human cells

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12 December 2020

Left ventricular function and remodeling after myocardial infarction in aging rats

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12 December 2020

Comparison of cardiac contractile and intracellular Ca2+ response between estrogen and phytoestrogen alpha-zearalanol in ventricular myocytes

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12 December 2020

Cardioprotection by chronic estrogen or superoxide dismutase mimetic treatment in the aged female rat.

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12 December 2020

Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression.

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12 December 2020

Long-term growth hormone deficiency as a cause of cardiomyopathy and its reversibility with specific replacement therapy

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12 December 2020

Growth hormone and the heart

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12 December 2020

Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension

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12 December 2020

Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover

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12 December 2020

Separate and joint influences of obesity and mild hypertension on left ventricular mass and geometry: The framingham heart study

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12 December 2020

Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases

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12 December 2020

Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning.

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12 December 2020

High glucose induces cardiac insulin-like growth factor I resistance in ventricular myocytes: role of Akt and ERK activation

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12 December 2020

Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure

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12 December 2020

Reactive oxygen species are downstream mediators of p53-dependent apoptosis

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12 December 2020

Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system

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12 December 2020

Chronic sympathetic activation: consequence and cause of age-associated obesity?

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12 December 2020

Aging enhances vascular dysfunction induced by the Alzheimer's peptide beta-amyloid

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12 December 2020

Enhanced peroxynitrite formation is associated with vascular aging

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12 December 2020

Loss of circadian rhythmicity in blood testosterone levels with aging in normal men

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12 December 2020

An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness.

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12 December 2020

Inflammatory markers and physical function among older adults with knee osteoarthritis

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12 December 2020

Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy

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12 December 2020

Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart

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12 December 2020

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12 December 2020

Gene therapy approaches for cardiovascular diseases.

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12 December 2020

Serum lipids, lipoprotein lp(a), and plasminogen activator inhibitor-1 in patients with Turner's syndrome before and during growth hormone and estrogen therapy

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12 December 2020

Growth hormone increases and insulin-like growth factor-I decreases circulating lipoprotein(a)

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12 December 2020

Alterations of antioxidant enzymes and oxidative stress markers in aging

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12 December 2020

Sex Hormones and Cardiomyopathic Phenotype Induced by Cardiac β2-Adrenergic Receptor Overexpression

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12 December 2020

Ras regulates NFAT3 activity in cardiac myocytes

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12 December 2020

Estrogen replacement therapy and protection from acute myocardial infarction

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12 December 2020

The p66shc adaptor protein controls oxidative stress response and life span in mammals

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12 December 2020

RAGE: a new pleiotropic antagonistic gene?

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12 December 2020

Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease

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12 December 2020

Cardiovascular effects of GH

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12 December 2020

[Calcium-binding activity of heart mitochondria in the aging rat and its possible role in myofibril relaxation]

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12 December 2020

Influence of age on inotropic response to insulin and insulin-like growth factor I in spontaneously hypertensive rats: role of nitric oxide

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12 December 2020

Identifiers

DOI

10.1385/ENDO:26:2:127

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Dimensions Publication ID

12 August 2017

1010636943

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