(Q36147356)

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Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice

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Europe PubMed Central

PMC publication ID

12 August 2017

Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice (English)

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Europe PubMed Central

PMC publication ID

12 August 2017

Ryan T Strachan

5

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Ryan T Strachan

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Europe PubMed Central

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12 August 2017

author name string

Rui Lin

1

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Europe PubMed Central

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12 August 2017

Simone Degan

2

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12 August 2017

Barbara S Theriot

3

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12 August 2017

Bernard M Fischer

4

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Europe PubMed Central

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12 August 2017

Jiurong Liang

6

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12 August 2017

Richard A Pierce

7

1 reference

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12 August 2017

Mary E Sunday

8

1 reference

Europe PubMed Central

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12 August 2017

Paul W Noble

9

1 reference

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12 August 2017

Monica Kraft

10

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Europe PubMed Central

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12 August 2017

Arnold R Brody

11

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12 August 2017

Julia K L Walker

12

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12 August 2017

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publication date

1 April 2012

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12 August 2017

British Journal of Pharmacology

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12 August 2017

165

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12 August 2017

7

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Europe PubMed Central

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12 August 2017

2365-2377

1 reference

Europe PubMed Central

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12 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3413869/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of β-receptor affinity in murine models of asthma

1 reference

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2 October 2017

β(2) -adrenoceptor agonists: current and future direction

1 reference

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2 October 2017

New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma

1 reference

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beta-Adrenoceptor inverse agonists in asthma

1 reference

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Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease

1 reference

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Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease

1 reference

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Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model

1 reference

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1 reference

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Beta-arrestins specifically constrain beta2-adrenergic receptor signaling and function in airway smooth muscle

1 reference

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Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model

1 reference

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Regulation of heterotrimeric G protein signaling in airway smooth muscle

1 reference

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Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal

1 reference

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Hyaluronan in tissue injury and repair

1 reference

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Targeting G protein-coupled receptor signaling in asthma

1 reference

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2 October 2017

Meta-analysis: effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths

1 reference

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2 October 2017

Beta2-agonist and anticholinergic drugs in the treatment of lung disease.

1 reference

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2 October 2017

The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors

1 reference

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2 October 2017

Long-acting beta-agonists: anti-inflammatory properties and synergy with corticosteroids in asthma

1 reference

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2 October 2017

Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma

1 reference

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2 October 2017

Benefit-risk assessment of long-acting beta2-agonists in asthma

1 reference

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2 October 2017

The β-adrenergic receptor kinase in heart failure

1 reference

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2 October 2017

Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox

1 reference

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2 October 2017

Beta-arrestin-2 regulates the development of allergic asthma

1 reference

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2 October 2017

Airway wall remodeling: friend or foe?

1 reference

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2 October 2017

Adverse effects of beta-agonists

1 reference

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2 October 2017

Beta-adrenergic receptor-mediated growth of human airway epithelial cell lines

1 reference

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2 October 2017

Resolution of lung inflammation by CD44

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2 October 2017

Is paradoxical pharmacology a strategy worth pursuing?

1 reference

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Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha)

1 reference

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2 October 2017

Regular inhaled salbutamol : effect on airway responsiveness to methacholine and adenosine 5'-monophosphate and tolerance to bronchoprotection

1 reference

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Enhancement of goblet cell hyperplasia and airway hyperresponsiveness by salbutamol in a rat model of atopic asthma

1 reference

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Regular inhaled salbutamol and asthma control: the TRUST randomised trial. Therapy Working Group of the National Asthma Task Force and the MRC General Practice Research Framework

1 reference

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Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo

1 reference

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Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors

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Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3

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Effect of long-term treatment with salmeterol on asthma control: a double blind, randomised crossover study

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Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients

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Is activation of the sympathetic nervous system beneficial or detrimental to the patient with chronic heart failure? Lessons learned from clinical trials with beta-adrenergic agonists and antagonists

1 reference

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Beta 1-adrenoceptors mediate smooth muscle relaxation in mouse isolated trachea

1 reference

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Distribution of beta 1- and beta 2-adrenoceptors in mouse trachea and lung: a quantitative autoradiographic study

1 reference

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The use of beta-agonists and the risk of death and near death from asthma

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Association between asthma mortality and isoproterenol aerosols: a review

1 reference

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Meta-analysis: effects of adding salmeterol to inhaled corticosteroids on serious asthma-related events

1 reference

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Interactive effects of steroids and beta-agonists on accumulation of type 2 T cells

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Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide

1 reference

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Airway mucosal thickening and bronchial hyperresponsiveness induced by inhaled beta 2-agonist in mice

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Retinoic acid attenuates O2-induced inhibition of lung septation

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23 September 2018

Transgenic overexpression of beta(2)-adrenergic receptors in airway epithelial cells decreases bronchoconstriction.

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23 September 2018

Morphometry explains variation in airway responsiveness in transgenic mice overexpressing interleukin-6 and interleukin-11 in the lung.

1 reference

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Atypical beta-adrenoceptor- (beta 3-adrenoceptor) mediated relaxation of canine isolated bronchial smooth muscle.

1 reference

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23 September 2018

Beta-adrenoceptor regulation and functional responses in the guinea-pig following chronic administration of the long-acting beta 2-adrenoceptor agonist formoterol.

1 reference

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23 September 2018

Expression of airway hyperreactivity to acetylcholine as a simple autosomal recessive trait in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regular inhaled salbutamol and airway responsiveness to allergen

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

End of the New Zealand asthma mortality epidemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A computer-controlled research ventilator for small animals: design and evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid Onset of Tolerance to the Bronchoprotective Effect of Salmeterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance to the bronchoprotective effect of salmeterol 12 hours after starting twice daily treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of treatment with formoterol on bronchoprotection against methacholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-acting inhaled beta 2-agonists and the loss of "bronchoprotective" efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-adrenoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salmeterol does not compromise the bronchodilator response to albuterol during acute episodes of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-agonist saga and its clinical relevance: on and on it goes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Airway remodeling in asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22013997

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2011.01725.X

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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