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STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function.
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Europe PubMed Central
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5045167
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
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24 March 2020
title
STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function
(English)
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Europe PubMed Central
PMC publication ID
5045167
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
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24 March 2020
main subject
OB-fold nucleic acid binding domain
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author
Anukana Bhattacharjee
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1
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Europe PubMed Central
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5045167
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retrieved
24 March 2020
author name string
Jason Stewart
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2
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Europe PubMed Central
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5045167
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
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24 March 2020
Mary Chaiken
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3
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5045167
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24 March 2020
Carolyn M Price
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4
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5045167
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24 March 2020
publication date
30 September 2016
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5045167
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retrieved
24 March 2020
published in
PLOS Genetics
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5045167
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retrieved
24 March 2020
volume
12
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Europe PubMed Central
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5045167
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24 March 2020
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9
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24 March 2020
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e1006342
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retrieved
24 March 2020
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Creative Commons Attribution 4.0 International
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30 September 2016
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ImageQuantTL
1 reference
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CZ Software Mentions: A large dataset of software mentions in the biomedical literature
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Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.
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The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
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The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch
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POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis
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The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening
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Diffusion of human replication protein A along single-stranded DNA.
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Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association
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Metabolism of DNA secondary structures at the eukaryotic replication fork
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CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis
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SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast
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RPA antagonizes microhomology-mediated repair of DNA double-strand breaks
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Causes and consequences of replication stress
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2 October 2017
Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication
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Molecular basis of telomere syndrome caused by CTC1 mutations
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2 October 2017
The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain
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2 October 2017
Human TEN1 maintains telomere integrity and functions in genome-wide replication restart
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CST for the grand finale of telomere replication.
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Structure of the Human Telomeric Stn1-Ten1 Capping Complex
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2 October 2017
The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures
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2 October 2017
Human CST has independent functions during telomere duplex replication and C-strand fill-in
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Structure and conformational change of a replication protein A heterotrimer bound to ssDNA
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2 October 2017
Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in
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Mutations in the telomere capping complex in bone marrow failure and related syndromes
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Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
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Human CST promotes telomere duplex replication and general replication restart after fork stalling
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2 October 2017
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends
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2 October 2017
The human CST complex is a terminator of telomerase activity
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2 October 2017
Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening
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2 October 2017
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
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Repair-specific functions of replication protein A.
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2 October 2017
Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract
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Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation
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Pre-calculated protein structure alignments at the RCSB PDB website
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Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α
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CST meets shelterin to keep telomeres in check
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Evolution of CST function in telomere maintenance
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Molecular steps of G-overhang generation at human telomeres and its function in chromosome end protection
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Telomeres: structures in need of unwinding
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Maintaining genome stability at the replication fork
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Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres
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Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain
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Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes
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2 October 2017
RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway
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Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells
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OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation
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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
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Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
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Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition
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Yeast telomere capping protein Stn1 overrides DNA replication control through the S phase checkpoint
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Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.
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Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats
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Functional analysis of the four DNA binding domains of replication protein A. The role of RPA2 in ssDNA binding
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The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein
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The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding
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2 October 2017
TRF2 Protects Human Telomeres from End-to-End Fusions
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A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions
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Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress
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Purification and properties of an accessory protein for DNA polymerase alpha/primase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5045167
retrieved
2 July 2018
Checkpoint regulation of replication dynamics in UV-irradiated human cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5045167
retrieved
23 September 2018
Elucidation of the DNA end-replication problem in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27690379
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An emerging role for the conserved telomere component 1 (CTC1) in human genetic disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27690379
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PGEN.1006342
1 reference
stated in
Europe PubMed Central
PMC publication ID
5045167
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 March 2020
PMC publication ID
5045167
1 reference
stated in
Europe PubMed Central
PMC publication ID
5045167
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 March 2020
PubMed publication ID
27690379
1 reference
stated in
Europe PubMed Central
PMC publication ID
5045167
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27690379%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 March 2020
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