(Q36161854)

12 August 2017

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title

Oxidative imbalance in Alzheimer's disease (English)

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12 August 2017

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6

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12 August 2017

1

Xiongwei Zhu

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12 August 2017

7

Mark A Smith

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12 August 2017

3

Gemma Casadesus

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12 August 2017

2

Hyoung-Gon Lee

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12 August 2017

4

Jesus Avila

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12 August 2017

Kelly Drew

5

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12 August 2017

1 January 2005

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12 August 2017

Molecular Neurobiology

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12 August 2017

31

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12 August 2017

205-217

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12 August 2017

1-3

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https://scigraph.springernature.com/pub.10.1385/mn:31:1-3:205

12 August 2017

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cites work

Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells

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12 December 2020

Oxidative stress increases expression and activity of BACE in NT2 neurons

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12 December 2020

Brain dysfunction in mild to moderate hypoxia.

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12 December 2020

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

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12 December 2020

Copernicus revisited: amyloid beta in Alzheimer's disease

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12 December 2020

Inhibition of Alzheimer beta-fibrillogenesis by melatonin

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12 December 2020

Does proteasome inhibition play a role in mediating neuropathology and neuron death in Alzheimer's disease?

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12 December 2020

The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease.

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12 December 2020

Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity.

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12 December 2020

Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions

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12 December 2020

Neurons may live for decades with neurofibrillary tangles.

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12 December 2020

Amyloid beta-protein toxicity and oxidative stress in Alzheimer's disease

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12 December 2020

Menadione-induced tau dephosphorylation in cultured human neuroblastoma cells.

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12 December 2020

Molecular pathology of head trauma: altered beta APP metabolism and the aetiology of Alzheimer's disease.

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12 December 2020

Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.

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12 December 2020

Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

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12 December 2020

Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease

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12 December 2020

Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal

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12 December 2020

Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.

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12 December 2020

Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease

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12 December 2020

Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD.

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12 December 2020

Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.

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12 December 2020

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

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12 December 2020

Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease

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12 December 2020

Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease

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12 December 2020

Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation

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12 December 2020

Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease.

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12 December 2020

Malondialdehyde, superoxide dismutase, melatonin, iron, copper, and zinc blood concentrations in patients with Alzheimer disease: cross-sectional study

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12 December 2020

Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants

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12 December 2020

A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains

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12 December 2020

Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity

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12 December 2020

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

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12 December 2020

A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage

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12 December 2020

Oxidative stress in Alzheimer's disease

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12 December 2020

Proteomic identification of nitrated proteins in Alzheimer's disease brain

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12 December 2020

Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

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12 December 2020

The cerebrospinal fluid oxidized NO metabolites, nitrite and nitrate, in Alzheimer's disease and vascular dementia of Binswanger type and multiple small infarct type.

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12 December 2020

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

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12 December 2020

Reactive oxygen species and the central nervous system

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12 December 2020

Oxidative damage is the earliest event in Alzheimer disease

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12 December 2020

The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients

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12 December 2020

Alzheimer's disease: the two-hit hypothesis

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12 December 2020

Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells

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12 December 2020

Oxidative damage to DNA in lymphocytes from AD patients.

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12 December 2020

Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage

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12 December 2020

Oxidative alterations in Alzheimer's disease.

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12 December 2020

Alterations in the interaction between iron regulatory proteins and their iron responsive element in normal and Alzheimer's diseased brains.

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12 December 2020

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

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12 December 2020

Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease.

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12 December 2020

Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.

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12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

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12 December 2020

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

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12 December 2020

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

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12 December 2020

Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?

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12 December 2020

Oxidative damage in Alzheimer's.

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12 December 2020

Oxidative stress, antioxidants, and Alzheimer disease

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12 December 2020

Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology.

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12 December 2020

Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease

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12 December 2020

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

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12 December 2020

Cell cycle markers in the hippocampus in Alzheimer's disease.

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12 December 2020

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

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12 December 2020

Elevated CSF prostaglandin E2 levels in patients with probable AD

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12 December 2020

Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle.

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12 December 2020

Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation

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12 December 2020

Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures.

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12 December 2020

Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine.

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12 December 2020

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

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12 December 2020

Electron transport chain defects in Alzheimer's disease brain.

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12 December 2020

Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease.

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12 December 2020

N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylation

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12 December 2020

Cerebrometabolic aspects of delirium in relationship to dementia

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12 December 2020

Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review.

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12 December 2020

Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF.

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12 December 2020

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

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12 December 2020

Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine

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12 December 2020

Oxidative stress hypothesis in Alzheimer's disease

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12 December 2020

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

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12 December 2020

Low plasma vitamin C in Alzheimer patients despite an adequate diet.

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12 December 2020

Chemistry and biochemistry of oxidative stress in neurodegenerative disease

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12 December 2020

Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease.

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12 December 2020

Alzheimer's disease and oxygen radicals: new insights

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12 December 2020

Early glycoxidation damage in brains from Down's syndrome.

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12 December 2020

Formation of aberrant phosphotau fibrillar polymers in neural cultured cells

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12 December 2020

The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain

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12 December 2020

Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease

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12 December 2020

DNA replication precedes neuronal cell death in Alzheimer's disease.

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12 December 2020

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12 December 2020

Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma

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12 December 2020

Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease

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12 December 2020

Tau, where are we now?

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12 December 2020

Increased CSF F2-isoprostane concentration in probable AD.

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12 December 2020

Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease.

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12 December 2020

Elemental imbalances in the olfactory pathway in Alzheimer's disease

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12 December 2020

Plasma protein glycation in Alzheimer's disease.

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12 December 2020

Comparison of neuropathologic criteria for the diagnosis of Alzheimer's disease.

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12 December 2020

Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease.

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12 December 2020

Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease.

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12 December 2020

Parkinson's disease is associated with oxidative stress: comparison of peripheral antioxidant profiles in living Parkinson's, Alzheimer's and vascular dementia patients

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12 December 2020

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

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12 December 2020

Abnormal localization of iron regulatory protein in Alzheimer's disease.

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12 December 2020

Free radical generation during brief period of cerebral ischemia may trigger delayed neuronal death

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12 December 2020

Static cytofluorometry and fluorescence morphology of mitochondria and DNA in proliferating fibroblasts

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12 December 2020

E-4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures

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12 December 2020

Decreased catalase activity but unchanged superoxide dismutase activity in brains of patients with dementia of Alzheimer type.

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12 December 2020

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

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12 December 2020

Abnormalities of mitochondrial enzymes in Alzheimer disease.

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12 December 2020

Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E.

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12 December 2020

Superoxide dismutase SOD1, encoded on chromosome 21, but not SOD2 is overexpressed in brains of patients with Down syndrome.

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12 December 2020

Antioxidant defences and oxidative stress markers in erythrocytes and plasma from normally nourished elderly Alzheimer patients

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12 December 2020

Oxidative stress induces dephosphorylation of tau in rat brain primary neuronal cultures.

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12 December 2020

4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau.

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12 December 2020

Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease.

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12 December 2020

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

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12 December 2020

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12 December 2020

Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain

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12 December 2020

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.

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12 December 2020

Recent advance in molecular iron metabolism: translational disorders of ferritin

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12 December 2020

Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease.

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12 December 2020

In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.

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12 December 2020

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

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12 December 2020

Oxidative damage in the olfactory system in Alzheimer's disease.

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12 December 2020

Reduced platelet cytochrome c oxidase activity in Alzheimer's disease.

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12 December 2020

Manganese and copper-zinc superoxide dismutases in the human olfactory mucosa: increased immunoreactivity in Alzheimer's disease

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12 December 2020

Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome

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12 December 2020

Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress.

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12 December 2020

Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo.

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12 December 2020

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

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12 December 2020

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

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12 December 2020

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

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12 December 2020

Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.

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12 December 2020

Evidence of neuronal oxidative damage in Alzheimer's disease.

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12 December 2020

Mitochondrial abnormalities in Alzheimer's disease.

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12 December 2020

Cell cycle events in neurons. Proliferation or death?

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12 December 2020

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

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12 December 2020

Identifiers

DOI

10.1385/MN:31:1-3:205

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PubMed ID

15953822

Dimensions Publication ID

12 August 2017

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1 reference

PubMed ID

15953822