Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36172124)
Watch
English
Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling.
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
title
Hepatitis C virus upregulates Beclin1 for induction of autophagy and activates mTOR signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
main subject
autophagy
0 references
Hepatitis C virus
1 reference
based on heuristic
inferred from title
hepatitis C
1 reference
based on heuristic
inferred from title
author
Shubham Shrivastava
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Ratna B Ray
series ordinal
5
object named as
Ratna B Ray
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author name string
Joydip Bhanja Chowdhury
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Robert Steele
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Ranjit Ray
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
language of work or name
English
0 references
publication date
6 June 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
volume
86
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
issue
16
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
page(s)
8705-8712
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
cites work
The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Autophagy protects cells from HCV-induced defects in lipid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
TFEB links autophagy to lysosomal biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Spatial coupling of mTOR and autophagy augments secretory phenotypes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
New insights into structure and replication of the hepatitis C virus and clinical implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Regulation of mammalian autophagy in physiology and pathophysiology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Endogenous HMGB1 regulates autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Viral interactions with macroautophagy: a double-edged sword
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Viruses and the autophagy machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
mTOR regulation of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The autophagy machinery is required to initiate hepatitis C virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Autophagy genes in immunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Pivotal role of mTOR signaling in hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Hepatitis C Virus Genotype 1a Growth and Induction of Autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Autophagy: from phenomenology to molecular understanding in less than a decade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Signalling through Class I PI3Ks in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
TSC2 mediates cellular energy response to control cell growth and survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
The phosphoinositide 3-kinase pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Synthesis and function of 3-phosphorylated inositol lipids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Phosphoinositide kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
1 October 2017
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
2 July 2018
Using structure to define the function of phosphoinositide 3-kinase family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421755
retrieved
2 July 2018
Identifiers
DOI
10.1128/JVI.00616-12
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PMC publication ID
3421755
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PubMed publication ID
22674982
1 reference
stated in
Europe PubMed Central
PMC publication ID
3421755
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22674982%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit