(Q36221012)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27956228%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice (English)

1 reference

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29 March 2020

0 references

3

1 reference

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29 March 2020

Jill Moore

4

1 reference

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29 March 2020

Yotsawat Pomyen

6

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29 March 2020

Soren H Hough

7

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29 March 2020

Zachary Kennedy

8

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29 March 2020

author name string

Chun-Qing Song

1

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29 March 2020

Yingxiang Li

2

1 reference

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29 March 2020

Angela Park

5

1 reference

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29 March 2020

Andrew Fischer

9

1 reference

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29 March 2020

Hao Yin

10

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29 March 2020

Daniel G Anderson

11

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29 March 2020

Darryl Conte

12

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29 March 2020

Lars Zender

13

1 reference

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29 March 2020

Xin Wei Wang

14

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29 March 2020

Snorri Thorgeirsson

15

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29 March 2020

Zhiping Weng

16

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29 March 2020

Wen Xue

17

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29 March 2020

language of work or name

English

0 references

publication date

10 December 2016

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29 March 2020

1 reference

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29 March 2020

volume

152

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29 March 2020

issue

5

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29 March 2020

page(s)

1161-1173.e1

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AEG-1 Promotes Metastasis Through Downstream AKR1C2 and NF1 in Liver Cancer

29 March 2020

cites work

1 reference

12 December 2020

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

1 reference

12 December 2020

Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target

1 reference

12 December 2020

Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer

1 reference

12 December 2020

WNT and beta-catenin signalling: diseases and therapies

1 reference

12 December 2020

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.

1 reference

12 December 2020

BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma.

1 reference

12 December 2020

Molecular pathogenesis of human hepatocellular carcinoma

1 reference

12 December 2020

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

1 reference

12 December 2020

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

1 reference

12 December 2020

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

1 reference

12 December 2020

Differential expression analysis for sequence count data

1 reference

12 December 2020

Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

1 reference

12 December 2020

The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

1 reference

12 December 2020

Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development

1 reference

12 December 2020

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

1 reference

12 December 2020

Functional and genetic deconstruction of the cellular origin in liver cancer.

1 reference

12 December 2020

Sorafenib in advanced hepatocellular carcinoma

1 reference

12 December 2020

Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

1 reference

12 December 2020

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

1 reference

12 December 2020

Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma

1 reference

12 December 2020

Hepatocellular carcinoma pathogenesis: from genes to environment

1 reference

12 December 2020

A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.

1 reference

12 December 2020

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

1 reference

12 December 2020

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

1 reference

12 December 2020

A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.

1 reference

12 December 2020

Applications of the CRISPR-Cas9 system in cancer biology

1 reference

12 December 2020

CRISPR-mediated direct mutation of cancer genes in the mouse liver

1 reference

12 December 2020

Global cancer statistics, 2012

1 reference

12 December 2020

Improved vectors and genome-wide libraries for CRISPR screening

1 reference

12 December 2020

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.

1 reference

12 December 2020

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

1 reference

12 December 2020

First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement

1 reference

12 December 2020

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

1 reference

12 December 2020

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

1 reference

12 December 2020

A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor

1 reference

12 December 2020

Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma

1 reference

12 December 2020

Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival

1 reference

12 December 2020

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

1 reference

12 December 2020

Plexin B1 is downregulated in renal cell carcinomas and modulates cell growth.

1 reference

12 December 2020

The Ras/MAPK pathway and hepatocarcinoma: pathogenesis and therapeutic implications

1 reference

12 December 2020

Application of comparative functional genomics to identify best-fit mouse models to study human cancer

1 reference

12 December 2020

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 reference

12 December 2020

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

1 reference

12 December 2020

The Cancer Genome Atlas Pan-Cancer analysis project

1 reference

12 December 2020

Suppression of lung adenocarcinoma progression by Nkx2-1

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

1 reference

12 December 2020

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

1 reference

12 December 2020

KRAS and YAP1 converge to regulate EMT and tumor survival

1 reference

12 December 2020

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells.

1 reference

12 December 2020

A versatile reporter system for CRISPR-mediated chromosomal rearrangements.

1 reference

12 December 2020

Roles of HMGA proteins in cancer

1 reference

12 December 2020

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

1 reference

12 December 2020

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

1 reference

12 December 2020

Genetic screens in human cells using the CRISPR-Cas9 system

1 reference

12 December 2020

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

1 reference

12 December 2020

10.1053/J.GASTRO.2016.12.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27956228%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

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29 March 2020

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