(Q36238466)

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A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4.

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Europe PubMed Central

PMC publication ID

13 August 2017

A peroxisome proliferator-activated receptor ligand MCC-555 imparts anti-proliferative response in pancreatic cancer cells by PPARgamma-independent up-regulation of KLF4. (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

pancreatic cancer

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inferred from title

author name string

Kyung-Won Min

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Xiaobo Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Temjenmongla Imchen

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Seung Joon Baek

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

30 June 2012

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Europe PubMed Central

PMC publication ID

13 August 2017

Toxicology and Applied Pharmacology

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Europe PubMed Central

PMC publication ID

13 August 2017

263

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

225-232

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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1 reference

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Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism

1 reference

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PPARγ ligands induce growth inhibition and apoptosis through p63 and p73 in human ovarian cancer cells

1 reference

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KLF4 is a novel candidate tumor suppressor gene in pancreatic ductal carcinoma.

1 reference

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Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.

1 reference

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Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

1 reference

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MCC-555-induced NAG-1 expression is mediated in part by KLF4.

1 reference

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1 reference

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Energy restriction as an antitumor target of thiazolidinediones

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Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice

1 reference

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Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways

1 reference

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5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells

1 reference

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PPARgamma and Apoptosis in Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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Gene alterations by peroxisome proliferator-activated receptor gamma agonists in human colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes inhibit growth, induce apoptosis, and decrease the androgen receptor in LNCaP prostate cancer cells through peroxisome proliferator-activated receptor gamma-independent pathways

1 reference

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Cellular and molecular consequences of peroxisome proliferator-activated receptor-gamma activation in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

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Genetics and biology of pancreatic ductal adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3443873

1 October 2017

KLF4, p21 and context-dependent opposing forces in cancer

1 reference

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1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes are peroxisome proliferator-activated receptor gamma agonists but decrease HCT-116 colon cancer cell survival through receptor-independent activation of early growth response-1 and nonsteroidal ant

1 reference

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Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat.

1 reference

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Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression

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Peroxisome proliferator-activated receptor-gamma (PPAR(gamma)) inhibits tumorigenesis by reversing the undifferentiated phenotype of metastatic non-small-cell lung cancer cells (NSCLC).

1 reference

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A novel PPAR alpha/gamma dual agonist inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.

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Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins

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RWJ-241947 (MCC-555), a unique peroxisome proliferator-activated receptor-gamma ligand with antitumor activity against human prostate cancer in vitro and in beige/nude/ X-linked immunodeficient mice and enhancement of apoptosis in myeloma cells indu

1 reference

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Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer

1 reference

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1 reference

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1 reference

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Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells

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22 September 2018

Peroxisome proliferator-activated receptor gamma induces pancreatic cancer cell apoptosis

1 reference

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1 reference

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The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC-555 treatment

1 reference

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Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22750490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel peroxisome proliferator-activated receptor gamma ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22750490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2012.06.014

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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