(Q36243860)

English

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

haploinsufficiency

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1 reference

based on heuristic

inferred from title

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

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Europe PubMed Central

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8 February 2020

Paulo A. Ferreira

5

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8 February 2020

author name string

Kyoung-In Cho

1

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8 February 2020

Kelly Searle

2

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8 February 2020

Mason Webb

3

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8 February 2020

publication date

21 July 2012

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8 February 2020

Cellular and Molecular Life Sciences

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8 February 2020

69

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8 February 2020

20

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8 February 2020

3511-3527

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8 February 2020

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

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Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress

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Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons

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1 October 2017

Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat.

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Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha

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1 October 2017

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1 October 2017

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Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I

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Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function

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1 October 2017

Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta

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1 October 2017

Identification of novel dendritic cell populations in normal mouse retina

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1 October 2017

Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis

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1 October 2017

Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease

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1 October 2017

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism

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1 October 2017

SOX2 is a dose-dependent regulator of retinal neural progenitor competence

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1 October 2017

Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption

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1 October 2017

Parkin ubiquitinates and promotes the degradation of RanBP2

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1 October 2017

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

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1 October 2017

Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription

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Carnitine acyltransferases and their influence on CoA pools in health and disease

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Potential for neural regeneration after neurotoxic injury in the adult mammalian retina

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1 October 2017

Methylthioadenosine.

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1 October 2017

Dopamine and retinal function

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1 October 2017

Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export

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1 October 2017

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

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1 October 2017

Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription

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1 October 2017

RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export.

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1 October 2017

Parkinson's disease: mechanisms and models

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1 October 2017

Autosomal dominant acute necrotizing encephalopathy

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Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

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1 October 2017

Mutations in NR4A2 associated with familial Parkinson disease

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1 October 2017

The nucleoporin RanBP2 has SUMO1 E3 ligase activity

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1 October 2017

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

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1 October 2017

The fundamental plan of the retina

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1 October 2017

Ubc9 interacts with a nuclear localization signal and mediates nuclear localization of the paired-like homeobox protein Vsx-1 independent of SUMO-1 modification

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1 October 2017

Carnosine-related dipeptides in neurons and glia.

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1 October 2017

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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1 October 2017

New animal models for Parkinson's disease

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1 October 2017

Final common pathways in neurodegenerative diseases: regulatory role of the glutathione cycle

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1 October 2017

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1

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1 October 2017

Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription

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1 October 2017

Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9

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1 October 2017

Microglia as mediators of inflammatory and degenerative diseases

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1 October 2017

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

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1 October 2017

RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex

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1 October 2017

Microglia: a sensor for pathological events in the CNS

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1 October 2017

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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1 October 2017

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

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1 October 2017

MPTP toxicity: implications for research in Parkinson's disease

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1 October 2017

Coenzyme A metabolism

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1 October 2017

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29 June 2018

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29 June 2018

Infection-triggered familial or recurrent cases of acute necrotizing encephalopathy caused by mutations in a component of the nuclear pore, RANBP2.

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29 June 2018

Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus.

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29 June 2018

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29 June 2018

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice.

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29 June 2018

Correlation between serum levels of some cholesterol precursors and activity of HMG-CoA reductase in human liver.

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29 June 2018

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

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29 June 2018

MPTP produces reversible disappearance of tyrosine hydroxylase-containing retinal amacrine cells

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29 June 2018

Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions.

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22 September 2018

Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.

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22 September 2018

Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice

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22 September 2018

Altered brain lipid composition in cyclooxygenase-2 knockout mouse

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22 September 2018

Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease.

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22 September 2018

Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo.

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22 September 2018

Glia cell number modulates sensitivity to MPTP in mice

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22 September 2018

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

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22 September 2018

The retina as a novel in vivo model for studying the role of molecules of the Bcl-2 family in relation to MPTP neurotoxicity

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22 September 2018

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

Developmental variation in the structure of the retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

The acute histopathology of MPTP in the mouse CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1071-9

21 January 2018

Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1071-9

21 January 2018

Mice lacking ornithine-delta-aminotransferase have paradoxical neonatal hypoornithinaemia and retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of MPTP on the mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal dopamine sensitivity to MPP+ toxicity: electrophysiological and biochemical evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-012-1071-9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

ResearchGate publication ID

0 references

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