(Q36268344)

13 August 2017

1 reference

title

Protease-activated receptors: potential therapeutic targets in irritable bowel syndrome? (English)

1 reference

13 August 2017

Romain Gloro

1

1 reference

13 August 2017

Philippe Ducrotte

series ordinal

2

1 reference

13 August 2017

Jean-Marie Reimund

series ordinal

3

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 October 2005

1 reference

Expert Opinion on Therapeutic Targets

13 August 2017

1 reference

13 August 2017

9

1 reference

13 August 2017

5

1 reference

13 August 2017

1079-1095

1 reference

AGA technical review on irritable bowel syndrome

13 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Irritable bowel syndrome in France: a common, debilitating and costly disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Costs of care for irritable bowel syndrome patients in a health maintenance organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The burden of selected digestive diseases in the United States.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Effects of stressful life events on bowel symptoms: subjects with irritable bowel syndrome compared with subjects without bowel dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Impaired transit and tolerance of intestinal gas in the irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Evidence for two distinct perceptual alterations in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Dysmotility of the small intestine in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Jejunal sensorimotor dysfunction in irritable bowel syndrome: clinical and psychosocial features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Anorectal manometry in irritable bowel syndrome: differences between diarrhoea and constipation predominant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The putative role of inflammation in the irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Inflammatory neuropathies of the enteric nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Stress and the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Regional cerebral activity in normal and pathological perception of visceral pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Anxiety and depression are related to autonomic nervous system function in women with irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Changes in tolerance to rectal distension correlate with changes in psychological state in patients with severe irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Treating irritable bowel syndrome: overview, perspective and future therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Protease-activated receptors: contribution to physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

G-protein-coupled receptors and signaling networks: emerging paradigms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The many faces of G protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Drug discovery: a historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Target validation of G-protein coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

A genomic perspective on human proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Molecular cloning of a potential proteinase activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

A dual thrombin receptor system for platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Cloning and characterization of human protease-activated receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Gastrointestinal functions of proteinase-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

PAR3 is a cofactor for PAR4 activation by thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The state of GPCR research in 2004.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Review article: proteinase-activated receptors - novel signals for gastrointestinal pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Mucosal pathophysiology and inflammatory changes in the late phase of the intestinal allergic reaction in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

A protective role of protease-activated receptor 1 in rat gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Suppression by protease-activated receptor-2 activation of gastric acid secretion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Protease-activated receptor-2 (PAR-2) in the rat gastric mucosa: immunolocalization and facilitation of pepsin/pepsinogen secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Capsazepine partially inhibits neurally mediated gastric mucus secretion following activation of protease-activated receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

2-Furoyl-LIGRL-NH2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

The protease-activated receptors and their cellular expression and function in blood-related cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinase-activated receptors: novel signals for peripheral nerves.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Evidence for the presence of functional protease activated receptor 4 (PAR4) in the rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Signal transduction pathways involved in the mechanical responses to protease-activated receptors in rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Protease-activated receptors mediate apamin-sensitive relaxation of mouse and guinea pig gastrointestinal smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Dual effect mediated by protease-activated receptors on the mechanical activity of rat colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Modulation of capsaicin-evoked visceral pain and referred hyperalgesia by protease-activated receptors 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Agonists of proteinase-activated receptor 2 excite guinea pig ileal myenteric neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Protease-activated receptors in inflammation, neuronal signaling and pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Thrombin Inhibits NMDA‐Mediated Nociceptive activity in the Mouse: Possible Mediation by Endothelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Modulation of visceral pain and inflammation by protease-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2 as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na+ absorption in the mouse distal colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.5.1079

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

21 January 2018

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI21689

Identifiers

DOI

10.1517/14728222.9.5.1079

1 reference

13 August 2017

1 reference