(Q36311166)

13 August 2017

1 reference

title

Multifocal angiostatic therapy: an update (English)

1 reference

13 August 2017

2

Keith I Block

1 reference

13 August 2017

Mark F McCarty

1

1 reference

13 August 2017

publication date

1 December 2005

1 reference

Integrative Cancer Therapies

13 August 2017

published in

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13 August 2017

volume

4

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13 August 2017

issue

4

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13 August 2017

page(s)

301-314

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A wholly nutritional 'multifocal angiostatic therapy' for control of disseminated cancer

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F1534735405282475

Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation

21 January 2018

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https://api.crossref.org/works/10.1177%2F1534735405282475

Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane

21 January 2018

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https://api.crossref.org/works/10.1177%2F1534735405282475

Therapeutic activity of 3,3'-diindolylmethane on prostate cancer in an in vivo model

21 January 2018

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https://api.crossref.org/works/10.1177%2F1534735405282475

3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic mice

21 January 2018

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https://api.crossref.org/works/10.1177%2F1534735405282475

3,3'-Diindolylmethane induces apoptosis in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

The use of silymarin in the treatment of liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Phase I trial of oral green tea extract in adult patients with solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin- and carboplatin-induced growth inhibition and apoptotic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Anti-angiogenic effect of silymarin on colon cancer LoVo cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Pharmacokinetic studies on IdB 1016, a silybin- phosphatidylcholine complex, in healthy human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Angiogenesis inhibited by drinking tea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Matrix metalloproteinase inhibition by green tea catechins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Phase I study of green tea extract in patients with advanced lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Copper lowering therapy with tetrathiomolybdate as an antiangiogenic strategy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Dietary glycine inhibits angiogenesis during wound healing and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Dietary glycine inhibits the growth of B16 melanoma tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Endothelial cells contain a glycine-gated chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Differential oxidation of protein-tyrosine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Endothelial membrane potential regulates production of both nitric oxide and superoxide--a fundamental determinant of vascular health.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Membrane depolarization and NADPH oxidase activation in aortic endothelium during ischemia reflect altered mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Thioredoxin reductase regulates angiogenesis by increasing endothelial cell-derived vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Thioredoxin inhibits tumor necrosis factor- or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Overexpression of thioredoxin reductase 1 regulates NF‐κB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Antiangiogenic activity of selenium in cancer chemoprevention: metabolite-specific effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Inorganic selenium retards progression of experimental hormone refractory prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Insulin-like growth factor I stimulates angiogenesis and the production of vascular endothelial growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Insulin-Like Growth Factor I (IGF-I) and IGF Binding Protein-1 Modulate Prostate Cancer Cell Growth and Apoptosis: Possible Mediators for the Effects of Diet and Exercise on Cancer Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate tumor cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Prevention of Cancer Through Lifestyle Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Intensive lifestyle changes may affect the progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Omega-3 polyunsaturated fatty acids in rodent models of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

n-3 polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Docosapentaenoic acid (22:5, n-3) suppressed tube-forming activity in endothelial cells induced by vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with n-3 fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Strategies for multiple signalling inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Therapeutic integration of signal transduction targeting agents and conventional anti-cancer treatments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

NF-kappaB mediates FGF signal regulation of msx-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Alpha 5 beta 1 integrin activates an NF-kappa B-dependent program of gene expression important for angiogenesis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Involvement of the transcription factor NF-kappaB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Tubular morphogenesis by genotoxic therapeutic agents that induce NF-kappaB activation in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

The alpha(v)beta3 integrin, NF-kappaB, osteoprotegerin endothelial cell survival pathway. Potential role in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Sulindac inhibits activation of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Host cyclooxygenase-2 modulates carcinoma growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

The role of COX-2 in angiogenesis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX‐2 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Role of Src expression and activation in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Herbimycin A inhibits angiogenic activity in endothelial cells and reduces neovascularization in a rat model of retinopathy of prematurity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

pp60(c-src) modulates microvascular endothelial phenotype and in vitro angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Src inhibitors: drugs for the treatment of osteoporosis, cancer or both?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

STAT proteins as novel targets for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Src-dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Overview: Translating Hsp90 Biology into Hsp90 Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Targeting multiple signal transduction pathways through inhibition of Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Altered states: selectively drugging the Hsp90 cancer chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Colorectal cancer and antiangiogenic therapy: what can be expected in clinical practice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Use of angiogenesis inhibitors in tumour treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

Tumor invasion: molecular shears blunted by green tea

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1534735405282475

21 January 2018

Identifiers

DOI

10.1177/1534735405282475

1 reference

13 August 2017

1 reference