(Q36312666)

English

Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Endogenous concentrations of ouabain act as a cofactor to stimulate fluid secretion and cyst growth of in vitro ADPKD models via cAMP and EGFR-Src-MEK pathways (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

Kyle Jansson

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Anh-Nguyet T Nguyen

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Brenda S Magenheimer

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Gail A Reif

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Lavakumar Reddy Aramadhaka

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Elsa Bello-Reuss

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Darren P Wallace

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

James P Calvet

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Gustavo Blanco

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

1 August 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

American Journal of Physiology - Renal Physiology

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

303

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

F982-90

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Cyclic AMP-mediated cyst expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Ouabain protects against adverse developmental programming of the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Signaling mechanisms that link salt retention to hypertension: endogenous ouabain, the Na(+) pump, the Na(+)/Ca(2+) exchanger and TRPC proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Molecular diagnostics for autosomal dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Clinical practice. Autosomal dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Vascular endothelium as a target for endogenous ouabain: studies on the effect of ouabain on human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

The Na,K-ATPase receptor complex: its organization and membership

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Polycystic kidney disease: genes, proteins, animal models, disease mechanisms and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Endogenous cardiac glycosides: hormones using the sodium pump as signal transducer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Molecular pathogenesis of ADPKD: the polycystin complex gets complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Polycystic kidney disease: new understanding in the pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Endogenous cardiac glycosides, a new class of steroid hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

The genetics and physiology of polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Relationship between Na(+),K(+)-ATPase and cell attachment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Chloride and fluid secretion by cultured human polycystic kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

Anion secretion drives fluid secretion by monolayers of cultured human polycystic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

30 September 2017

The effect of caffeine on renal epithelial cells from patients with autosomal dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

29 June 2018

Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

29 June 2018

Mechanisms of progression in autosomal dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

29 June 2018

Pathogenesis of autosomal dominant polycystic kidney disease: recent developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

29 June 2018

Physiological roles of endogenous ouabain in normal rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

KCa3.1 potassium channels are critical for cAMP-dependent chloride secretion and cyst growth in autosomal-dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Regulation of apical NHE3 trafficking by ouabain-induced activation of the basolateral Na+-K+-ATPase receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

The pathogenesis of autosomal dominant polycystic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Adrenergic regulation of salt and fluid secretion in human medullary collecting duct cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Low concentrations of ouabain activate vascular smooth muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Positive inotropic effect of ouabain on isolated heart is accompanied by activation of signal pathways that link Na+/K+-ATPase to ERK1/2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Sulfonylurea-sensitive K(+) transport is involved in Cl(-) secretion and cyst trowth by cultured ADPKD cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Electrolyte and fluid secretion by cultured human inner medullary collecting duct cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Polycystic kidney disease: from the bedside to the gene and back.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469686

22 September 2018

cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical modification of cell proliferation and fluid secretion in renal cysts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secretion of fluid by renal cysts from patients with autosomal dominant polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloride and fluid secretion in polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial transport in polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early embryonic renal tubules of wild-type and polycystic kidney disease kidneys respond to cAMP stimulation with cystic fibrosis transmembrane conductance regulator/Na(+),K(+),2Cl(-) Co-transporter-dependent cystic dilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPRENAL.00677.2011

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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