(Q36348742)

13 August 2017

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title

Limiting inflammatory responses during activation of innate immunity (English)

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13 August 2017

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Jiahuai Han

1

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13 August 2017

Richard J Ulevitch

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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13 August 2017

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13 August 2017

volume

6

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13 August 2017

issue

12

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13 August 2017

page(s)

1198-1205

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13 August 2017

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Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

21 January 2018

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A Toll-like receptor recognizes bacterial DNA

21 January 2018

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Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy

21 January 2018

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Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

21 January 2018

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Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms

21 January 2018

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Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

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An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

21 January 2018

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

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Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

21 January 2018

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TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

21 January 2018

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The CARD domain: a new apoptotic signalling motif

21 January 2018

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CARD15 mutations in Blau syndrome

21 January 2018

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

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Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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Genetic analysis of innate immunity: identification and function of the TIR adapter proteins

21 January 2018

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The NOD: a signaling module that regulates apoptosis and host defense against pathogens

21 January 2018

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IRAK-4 as the central TIR signaling mediator in innate immunity

21 January 2018

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TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

21 January 2018

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RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

21 January 2018

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Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1

21 January 2018

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 January 2018

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NF-kappaB regulation in the immune system

21 January 2018

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

21 January 2018

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The IKK NF-kappa B system: a treasure trove for drug development

21 January 2018

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How MAP kinases are regulated

21 January 2018

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TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1

21 January 2018

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MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

21 January 2018

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Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases

21 January 2018

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The JNK signal transduction pathway

21 January 2018

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Targeting JNK for therapeutic benefit: from junk to gold?

21 January 2018

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Inhibition of p38 MAP kinase as a therapeutic strategy

21 January 2018

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Activation and signaling of the p38 MAP kinase pathway

21 January 2018

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Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38.

21 January 2018

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

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Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

21 January 2018

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Transcription factors as potential targets for therapeutic drugs

21 January 2018

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Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

21 January 2018

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Control of mRNA decay by heat shock-ubiquitin-proteasome pathway

21 January 2018

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Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

21 January 2018

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Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA.

21 January 2018

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Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

21 January 2018

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

21 January 2018

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

21 January 2018

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Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1

21 January 2018

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Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

21 January 2018

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c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells

21 January 2018

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The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

21 January 2018

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Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA.

21 January 2018

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MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

21 January 2018

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MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding

21 January 2018

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MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

21 January 2018

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Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

21 January 2018

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Regulated ARE-mediated mRNA decay in Saccharomyces cerevisiae

21 January 2018

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Involvement of microRNA in AU-rich element-mediated mRNA instability

21 January 2018

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Argonaute2, a link between genetic and biochemical analyses of RNAi

21 January 2018

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A micrococcal nuclease homologue in RNAi effector complexes

21 January 2018

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Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability

21 January 2018

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Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line.

21 January 2018

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Negative regulation of toll-like receptor-mediated immune responses

21 January 2018

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Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors

21 January 2018

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Aberrant Toll receptor expression and endotoxin hypersensitivity in mice lacking a functional TGF-beta 1 signaling pathway

21 January 2018

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Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

21 January 2018

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Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

21 January 2018

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ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance

21 January 2018

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Expression of ST2, an interleukin-1 receptor homologue, is induced by proinflammatory stimuli

21 January 2018

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A novel pathway regulating lipopolysaccharide-induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression

21 January 2018

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Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

21 January 2018

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SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

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IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

21 January 2018

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Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

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Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

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IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

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The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory

21 January 2018

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MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression

21 January 2018

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TRAIL-R as a negative regulator of innate immune cell responses.

21 January 2018

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PI3K and negative regulation of TLR signaling.

21 January 2018

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Characterization of Tollip protein upon Lipopolysaccharide challenge

21 January 2018

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Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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A20 is a negative regulator of IFN regulatory factor 3 signaling.

21 January 2018

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Regulation and role of transforming growth factor-beta in immune tolerance induction and inflammation.

21 January 2018

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Interleukin-10 therapy--review of a new approach

21 January 2018

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PPARs as drug targets to modulate inflammatory responses?

21 January 2018

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IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

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The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense

21 January 2018

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7 January 2021

Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B

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7 January 2021

p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes

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7 January 2021

The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

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7 January 2021

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

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7 January 2021

Gene suppression by tristetraprolin and release by the p38 pathway

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7 January 2021

Oxidized Phospholipids Negatively Regulate Dendritic Cell Maturation Induced by TLRs and CD40

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7 January 2021

Suppressors of cytokine signalling (SOCS) in the immune system

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7 January 2021

Identifiers

DOI

10.1038/NI1274

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13 August 2017

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