(Q36358858)

13 August 2017

1 reference

title

Clinical potential of GABAB receptor modulators (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

author name string

Jennifer Ong

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

David I B Kerr

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

publication date

1 January 2005

1 reference

CNS Neuroscience & Therapeutics

13 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

page(s)

317-334

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

Baclofen suppresses motivation to consume alcohol in rats

12 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2005.TB00049.X

Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2005.TB00049.X

Effects of the calmodulin antagonists fendiline and calmidazolium on aggregation, secretion of ATP, and internal calcium in washed human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2005.TB00049.X

Fendiline inhibits L-type calcium channels in guinea-pig ventricular myocytes: a whole-cell patch-clamp study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2005.TB00049.X

Implication of the GABA(B) receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine.

21 January 2018

1 reference

12 December 2020

Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release.

1 reference

12 December 2020

Ability of baclofen in reducing alcohol craving and intake: II--Preliminary clinical evidence.

1 reference

12 December 2020

Fendiline increases [Ca2+]i in Madin Darby canine kidney (MDCK) cells by releasing internal Ca2+ followed by capacitative Ca2+ entry

1 reference

12 December 2020

Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules

1 reference

12 December 2020

The anti-anginal drug fendiline increases intracellular Ca(2+) levels in MG63 human osteosarcoma cells

1 reference

12 December 2020

Modification of d-amphetamine-induced responses by baclofen in rats

1 reference

12 December 2020

Dual effect of the antianginal drug fendiline on bladder female transitional carcinoma cells: mobilization of intracellular CA2+ and induction of cell death

1 reference

12 December 2020

Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice

1 reference

12 December 2020

Fendiline, an anti-anginal drug, increases intracellular Ca2+ in PC3 human prostate cancer cells

1 reference

12 December 2020

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).

1 reference

12 December 2020

Fendiline mobilizes intracellular Ca2+ in Chang liver cells

1 reference

12 December 2020

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site

1 reference

12 December 2020

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

1 reference

12 December 2020

Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease

1 reference

12 December 2020

Attenuation of morphine withdrawal signs by the GABA(B) receptor agonist baclofen

1 reference

12 December 2020

Immunohistochemical localization of GABAB receptor in the entorhinal cortex and inferior temporal cortex of schizophrenic brain

1 reference

12 December 2020

GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings

1 reference

12 December 2020

Rapid suppression of alcohol withdrawal syndrome by baclofen.

1 reference

12 December 2020

Metabotropic glutamate and GABA(B) receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells.

1 reference

12 December 2020

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

1 reference

12 December 2020

International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function

1 reference

12 December 2020

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

1 reference

12 December 2020

Patterns of cocaine self-administration in rats produced by various access conditions under a discrete trials procedure

1 reference

12 December 2020

Baclofen decreases methamphetamine self-administration in rats

1 reference

12 December 2020

A potential role for GABA(B) agonists in the treatment of psychostimulant addiction

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12 December 2020

Baclofen antagonizes intravenous self-administration of nicotine in mice and rats

1 reference

12 December 2020

Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study

1 reference

12 December 2020

Arylalkylamines are a novel class of positive allosteric modulators at GABA(B) receptors in rat neocortex

1 reference

12 December 2020

GABA(B) receptor function in the ileum and urinary bladder of wildtype and GABA(B1) subunit null mice.

1 reference

12 December 2020

Drug levels: therapeutic and toxic serum/plasma concentrations of common drugs

1 reference

12 December 2020

The GABA(B) receptor agonist baclofen attenuates cocaine- and heroin-seeking behavior by rats

1 reference

12 December 2020

Suppression by baclofen of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats

1 reference

12 December 2020

Potentiation of metabotropic GABAB receptors by l-amino acids and dipeptides in rat neocortex

1 reference

12 December 2020

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors

1 reference

12 December 2020

GABA(B) receptors as potential therapeutic targets

1 reference

12 December 2020

Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat

1 reference

12 December 2020

GABAergic dysfunction in mood disorders.

1 reference

12 December 2020

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

1 reference

12 December 2020

Effects of GABA agonists on body temperature regulation in GABA(B(1))-/- mice

1 reference

12 December 2020

GABA(B) receptor activation in the ventral tegmental area inhibits the acquisition and expression of opiate-induced motor sensitization

1 reference

12 December 2020

The GABA B receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat

1 reference

12 December 2020

Increased expression of gamma-aminobutyric acid type B receptors in the hippocampus of patients with temporal lobe epilepsy

1 reference

12 December 2020

GABA(B1a), GABA(B1b) AND GABA(B2) mRNA variants expression in hippocampus resected from patients with temporal lobe epilepsy.

1 reference

12 December 2020

Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats

1 reference

12 December 2020

Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine use.

1 reference

12 December 2020

Selected amino acids, dipeptides and arylalkylamine derivatives do not act as allosteric modulators at GABAB receptors.

1 reference

12 December 2020

Progress with novel pharmacological strategies for gastro-oesophageal reflux disease.

1 reference

12 December 2020

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

1 reference

12 December 2020

Baclofen prevents MDMA-induced rise in core body temperature in rats

1 reference

12 December 2020

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

1 reference

12 December 2020

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

1 reference

12 December 2020

Calcimimetic and calcilytic drugs: just for parathyroid cells?

1 reference

12 December 2020

GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin

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12 December 2020

Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.

1 reference

12 December 2020

Molecular structure and physiological functions of GABA(B) receptors

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12 December 2020

Immunocytochemical localization of GABABR1 receptor subunits in the basolateral amygdala

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12 December 2020

Baclofen as adjunctive treatment for a patient with cocaine dependence and schizoaffective disorder

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12 December 2020

Activation mechanism of the heterodimeric GABA(B) receptor

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12 December 2020

The GABAB2 subunit is critical for the trafficking and function of native GABAB receptors

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12 December 2020

In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor

1 reference

12 December 2020

Role of GABAB receptor in alcohol dependence: Reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics

1 reference

12 December 2020

Allosteric modulation of GABA(B) receptor function in human frontal cortex.

1 reference

12 December 2020

Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression.

1 reference

12 December 2020

Attenuation of d-amphetamine self-administration by baclofen in the rat: behavioral and neurochemical correlates

1 reference

12 December 2020

Novel approaches to the treatment of cocaine addiction

1 reference

12 December 2020

3-Chloro,4-methoxyfendiline is a potent GABA(B) receptor potentiator in rat neocortical slices

1 reference

12 December 2020

Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains

1 reference

12 December 2020

GABA(B) receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area

1 reference

12 December 2020

Safety and efficacy of GABAergic medications for treating alcoholism

1 reference

12 December 2020

Changes in hippocampal GABABR1 subunit expression in Alzheimer's patients: association with Braak staging.

1 reference

12 December 2020

Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence

1 reference

12 December 2020

The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat.

1 reference

12 December 2020

Immunohistochemical and immunoblot analysis of gamma-aminobutyric acid B receptor in the prefrontal cortex of subjects with schizophrenia and bipolar disorder

1 reference

12 December 2020

Is the GABA B heterodimer a good drug target?

1 reference

12 December 2020

Preclinical evidence for GABAB agonists as a pharmacotherapy for cocaine addiction

1 reference

12 December 2020

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1 reference

12 December 2020

Functional in vitro test of calmodulin antagonism: effect of drugs on interaction between calmodulin and glycolytic enzymes

1 reference

12 December 2020

GABAA and GABAB receptor site distribution in the rat central nervous system

1 reference

12 December 2020

Fendiline: a review of its basic pharmacological and clinical properties.

1 reference

12 December 2020

Tolerance and pharmacokinetics of oral fendiline

1 reference

12 December 2020

A drug with antispastic action on striated muscle. Clinical trial of a derivative of GABA

1 reference

12 December 2020

Single dose pharmacokinetics of fendiline in humans

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12 December 2020

Characterization of GABAB ligands in vivo

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12 December 2020

New drug binding sites in Ca2+ channels

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12 December 2020

CGP 36742: the first orally active GABAB blocker improves the cognitive performance of mice, rats, and rhesus monkeys

1 reference

12 December 2020

The GABAB receptor antagonist CGP 36,742 and the nootropic oxiracetam facilitate the formation of long-term memory.

1 reference

12 December 2020

Baclofen attenuates the reinforcing effects of cocaine in rats.

1 reference

12 December 2020

The GABA(B) receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rats

1 reference

12 December 2020

The calcium-sensing receptor: insights into extracellular calcium homeostasis in health and disease

1 reference

12 December 2020

Calcimimetics with potent and selective activity on the parathyroid calcium receptor

1 reference

12 December 2020

Baclofen as a cocaine anti-craving medication: a preliminary clinical study.

1 reference

12 December 2020

Open state block by fendiline of L-type Ca++ channels in ventricular myocytes from rat heart.

1 reference

12 December 2020

The GABAB agonist baclofen modifies cocaine self-administration in rats.

1 reference

12 December 2020

10.1111/J.1527-3458.2005.TB00049.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741760&resulttype=core&format=json

12 May 2020

1 reference