(Q36366471)

24 June 2018

title

Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome (English)

1 reference

24 June 2018

1 reference

Grant W Brown

6

0 references

author name string

Keith Wheaton

1

1 reference

24 June 2018

Denise Campuzano

2

1 reference

24 June 2018

Weili Ma

3

1 reference

24 June 2018

Michal Sheinis

4

1 reference

24 June 2018

Brandon Ho

5

1 reference

24 June 2018

Samuel Benchimol

7

1 reference

24 June 2018

language of work or name

English

0 references

publication date

29 June 2017

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24 June 2018

Molecular and Cellular Biology

published in

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24 June 2018

volume

37

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24 June 2018

issue

14

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24 June 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5492170/fullTextXML

inferred from PubMed Central ID database lookup

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2 July 2018

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2 July 2018

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2 July 2018

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DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A.

2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

2 July 2018

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2 July 2018

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Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

2 July 2018

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Genomic instability in laminopathy-based premature aging

2 July 2018

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The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

The signals and pathways activating cellular senescence

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Reversal of human cellular senescence: roles of the p53 and p16 pathways

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

A system for stable expression of short interfering RNAs in mammalian cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Nuclear organization of DNA replication in primary mammalian cells.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

The establishment of telomerase-immortalized cell lines representing human chromosome instability syndromes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Extension of life-span by introduction of telomerase into normal human cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Telomere length predicts replicative capacity of human fibroblasts

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5492170

Genome instability in progeria: when repair gets old

22 September 2018

1 reference

12 December 2020

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

12 December 2020

Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths

1 reference

12 December 2020

Telomeres limit cancer growth by inducing senescence: long-sought in vivo evidence obtained

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00659-16

1 reference

24 June 2018

release_moad4cos55frfcwog2zcbljbxm

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/moad4cos55frfcwog2zcbljbxm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

5492170

1 reference

24 June 2018

PubMed publication ID

28483909

1 reference

24 June 2018