(Q36379376)

13 August 2017

1 reference

title

Targeting Aurora kinases in ovarian cancer (English)

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13 August 2017

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Siqing Fu

1

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Robert C. Bast

object named as

Robert C Bast

series ordinal

4

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author name string

Wei Hu

series ordinal

2

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13 August 2017

John J Kavanagh

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 February 2006

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Expert Opinion on Therapeutic Targets

13 August 2017

published in

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13 August 2017

volume

10

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13 August 2017

issue

1

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13 August 2017

page(s)

77-85

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https://api.crossref.org/works/10.1517%2F14728222.10.1.77

13 August 2017

1 reference

Cell division: feeling tense enough?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-A - a guardian of poles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora A, meiosis and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

The clinical significance of Aurora-A/STK15/BTAK expression in human esophageal squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Overexpression and amplification of Aurora-A in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-kinase inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

The Aurora kinases: role in cell transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Chfr is required for tumor suppression and Aurora A regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Amplification and overexpression of aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Progress in the development of selective inhibitors of Aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Progress in the development of selective inhibitors of aurora kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Aurora kinase inhibitor ZM447439 blocks chromosome-induced spindle assembly, the completion of chromosome condensation, and the establishment of the spindle integrity checkpoint in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Mechanism of Aurora B activation by INCENP and inhibition by hesperadin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Crystal structure of aurora-2, an oncogenic serine/threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

Surgeons as an Integral Part of the Cancer Research Team

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.1.77

21 January 2018

Identifiers

DOI

10.1517/14728222.10.1.77

1 reference

13 August 2017

1 reference