(Q36381270)

13 August 2017

1 reference

title

BRCA1-associated complexes: new targets to overcome breast cancer radiation resistance (English)

1 reference

13 August 2017

Xiaowei Chen

1

1 reference

PubMed ID

16445371

13 August 2017

Cletus A Arciero

series ordinal

2

1 reference

PubMed ID

16445371

13 August 2017

Andrew K Godwin

series ordinal

3

1 reference

13 August 2017

1 February 2006

1 reference

Expert Review of Anticancer Therapy

13 August 2017

1 reference

13 August 2017

6

1 reference

13 August 2017

2

1 reference

13 August 2017

187-196

1 reference

13 August 2017

Cancer statistics, 2005

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 mutations in primary breast and ovarian carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Linkage of early-onset familial breast cancer to chromosome 17q21

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Classification of BRCA1 missense variants of unknown clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Genetic analysis of BRCA1 function in a defined tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Primary fibroblasts from BRCA1 heterozygotes display an abnormal G1/S cell cycle checkpoint following UVA irradiation but show normal levels of micronuclei following oxidative stress or mitomycin C treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1 interacts with components of the histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

The role of BRCA1 in the cellular response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Molecular functions of BRCA1 in the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

True recurrence vs. new primary ipsilateral breast tumor relapse: an analysis of clinical and pathologic differences and their implications in natural history, prognoses, and therapeutic management

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Chromosomal radiosensitivity in BRCA1 and BRCA2 mutation carriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Lack of RB protein correlates with increased sensitivity to UV-radiation-induced apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Modulation of radiation response by histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Interaction of FANCD2 and NBS1 in the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

Mutation analysis of BRCA1 and BRCA2 cancer predisposition genes in radiation hypersensitive cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.6.2.187

21 January 2018

Identifiers

DOI

10.1586/14737140.6.2.187

1 reference

13 August 2017

1 reference

PubMed ID

16445371