(Q36395100)

13 August 2017

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title

Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer (English)

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13 August 2017

Erika M Wolff

1

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13 August 2017

Gangning Liang

series ordinal

2

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13 August 2017

Peter A Jones

series ordinal

3

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13 August 2017

language of work or name

English

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publication date

1 October 2005

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13 August 2017

Nature Reviews Urology

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13 August 2017

2

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13 August 2017

10

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13 August 2017

502-510

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https://scigraph.springernature.com/pub.10.1038/ncpuro0318

13 August 2017

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cites work

Bladder cancer. I. Molecular and genetic basis of carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

What we could do now: molecular pathology of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Connecting proliferation and apoptosis in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

EGFR and cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Review Article: The Role of Ras Superfamily Proteins in Bladder Cancer Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

The E2F transcriptional network: old acquaintances with new faces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Human urinary bladder epithelial cells lacking wild-type p53 function are deficient in the repair of 4-aminobiphenyl-DNA adducts in genomic DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

DBCCR1 mediates death in cultured bladder tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Transcription repression in oncogenic transformation: common targets of epigenetic repression in cells transformed by Fos, Ras or Dnmt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Induction of centrosome amplification and chromosome instability in human bladder cancer cells by p53 mutation and cyclin E overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Identification of chromosome 9 alterations and p53 accumulation in isolated carcinoma in situ of the urinary bladder versus carcinoma in situ associated with carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Identifying distinct classes of bladder carcinoma using microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

The genetics of transitional cell carcinoma: progress and potential clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

The fundamental role of epigenetic events in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

Molecular pathways in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Detection of bladder cancer in urine by a tumor suppressor gene hypermethylation panel

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

FrequentFGFR3mutations in urothelial papilloma

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: contribution of exogenous versus endogenous carcinogens.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

RB regulates transcription of the p21/WAF1/CIP1 gene

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Molecular evolution of multiple recurrent cancers of the bladder

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0318

7 January 2021

Identifiers

DOI

10.1038/NCPURO0318

1 reference

Dimensions Publication ID

13 August 2017

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1 reference