(Q36402295)

14 August 2017

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title

Engineering biosynthetic pathways to generate antitumor indolocarbazole derivatives (English)

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14 August 2017

César Sánchez

1

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Carmen Méndez

object named as

Carmen Méndez

series ordinal

2

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author name string

José A Salas

series ordinal

3

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14 August 2017

publication date

21 February 2006

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Journal of Industrial Microbiology & Biotechnology

14 August 2017

published in

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14 August 2017

volume

33

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14 August 2017

issue

7

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14 August 2017

page(s)

560-568

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Revival of the genus Lentzea and proposal for Lechevalieria gen. nov.

14 August 2017

cites work

1 reference

Crossref

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3'-Demethoxy-3'-hydroxystaurosporine-O-methyltransferase from Streptomyces longisporoflavus catalyzing the last step in the biosynthesis of staurosporine

21 January 2018

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Crossref

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Isolation and synthesis of biologically active carbazole alkaloids

21 January 2018

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12 December 2020

Microbial biosynthesis of halometabolites

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12 December 2020

Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243

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12 December 2020

Enzymatic assembly of the bis-indole core of rebeccamycin

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12 December 2020

Isolation of a bromo analog of rebeccamycin from Saccharothrix aerocolonigenes

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12 December 2020

A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.

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12 December 2020

Discovery of antitumor indolocarbazoles: rebeccamycin, NSC 655649, and fluoroindolocarbazoles

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12 December 2020

Cytochrome P450 homolog is responsible for C-N bond formation between aglycone and deoxysugar in the staurosporine biosynthesis of Streptomyces sp. TP-A0274.

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12 December 2020

Generation of hybrid elloramycin analogs by combinatorial biosynthesis using genes from anthracycline-type and macrolide biosynthetic pathways

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12 December 2020

Natural products to drugs: natural product derived compounds in clinical trials

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12 December 2020

The biosynthesis of indolocarbazoles in a heterologous E. coli host.

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12 December 2020

Combinatorial biosynthesis of antitumor indolocarbazole compounds

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12 December 2020

Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT.

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12 December 2020

Rebeccamycin analogues as anti-cancer agents

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12 December 2020

Biosynthesis of staurosporine, 2. Incorporation of tryptophan

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12 December 2020

Streptomyces albus G Mutants Defective in the SalGI Restriction-Modification System

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12 December 2020

Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase

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12 December 2020

Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

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12 December 2020

Cloning and expression of a gene encoding N-glycosyltransferase (ngt) from Saccarothrix aerocolonigenes ATCC39243.

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12 December 2020

Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.

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12 December 2020

Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.

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12 December 2020

Engineering deoxysugar biosynthetic pathways from antibiotic-producing microorganisms. A tool to produce novel glycosylated bioactive compounds

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12 December 2020

A new shuttle cosmid vector, pKC505, for streptomycetes: its use in the cloning of three different spiramycin-resistance genes from a Streptomyces ambofaciens library

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12 December 2020

Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem action of RebO and RebD.

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12 December 2020

UCN-01 (7-hydroxystaurosporine) and other indolocarbazole compounds: a new generation of anti-cancer agents for the new century?

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12 December 2020

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives

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12 December 2020

Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp.

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12 December 2020

The biosynthetic origins of rebeccamycin

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12 December 2020

Indole Pigments from the Fruiting Bodies of the Slime MoldArcyria denudata

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9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/ANIE.198004591

A New Metabolite of Tryptophan, Chromopyrrolic Acid, Produced byChromobacterium violaceum

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1271/BBB.57.775

Identifiers

DOI

10.1007/S10295-006-0092-5

1 reference

14 August 2017

1 reference