(Q33897278)

English

Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase (English)

1 reference

Europe PubMed Central

29 July 2017

César Sánchez

object named as

César Sánchez

3

0 references

Alfredo F. Braña

object named as

Alfredo F Braña

4

0 references

object named as

Carmen Méndez

6

0 references

author name string

Aaroa P Salas

1

1 reference

Europe PubMed Central

29 July 2017

Lili Zhu

2

1 reference

Europe PubMed Central

29 July 2017

Jürgen Rohr

5

1 reference

Europe PubMed Central

29 July 2017

José A Salas

7

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 October 2005

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Europe PubMed Central

29 July 2017

Molecular Microbiology

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Europe PubMed Central

29 July 2017

58

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Europe PubMed Central

29 July 2017

17-27

1 reference

Europe PubMed Central

29 July 2017

1

1 reference

Europe PubMed Central

29 July 2017

Combinatorial biosynthesis of antitumor indolocarbazole compounds

1 reference

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28 July 2018

Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

28 July 2018

The biosynthesis of indolocarbazoles in a heterologous E. coli host.

1 reference

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28 July 2018

Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin

1 reference

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28 July 2018

UCN-01 (7-hydroxystaurosporine) and other indolocarbazole compounds: a new generation of anti-cancer agents for the new century?

1 reference

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28 July 2018

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

1 reference

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28 July 2018

3'-Demethoxy-3'-hydroxystaurosporine-O-methyltransferase from Streptomyces longisporoflavus catalyzing the last step in the biosynthesis of staurosporine

1 reference

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28 July 2018

Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

1 reference

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28 July 2018

Further minor metabolites of staurosporine produced by a Streptomyces longisporoflavus strain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

28 July 2018

Streptomyces albus G Mutants Defective in the SalGI Restriction-Modification System

1 reference

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28 July 2018

Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

1 reference

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28 July 2018

A new shuttle cosmid vector, pKC505, for streptomycetes: its use in the cloning of three different spiramycin-resistance genes from a Streptomyces ambofaciens library

1 reference

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28 July 2018

Plasmid cloning vectors that integrate site-specifically in Streptomyces spp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

28 July 2018

Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides

1 reference

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29 October 2018

Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine

1 reference

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29 October 2018

Engineering deoxysugar biosynthetic pathways from antibiotic-producing microorganisms. A tool to produce novel glycosylated bioactive compounds

1 reference

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29 October 2018

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

DesVI: A New Member of the Sugar N,N-Dimethyltransferase Family Involved in the Biosynthesis of Desosamine The authors gratefully acknowledge financial support provided by the National Institutes of Health (GM 54346). H.-w.L. also thanks the Nationa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Staurosporine analogues - pharmacological toys or useful antitumour agents?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881644

29 October 2018

Further metabolic studies of indole and sugar derivatives using the staurosporine producer Streptomyces staurosporeus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of the staurosporine aglycon K-252c with a blocked mutant of the staurosporine producer strain Streptomyces longisporoflavus and by biotransformation of staurosporine with Streptomyces mediocidicus ATCC 13279

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of hybrid elloramycin analogs by combinatorial biosynthesis using genes from anthracycline-type and macrolide biosynthetic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structures of the novel protein kinase C inhibitors K-252a, b, c and d

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3'-Demethoxy-3'-hydroxystaurosporine, a novel staurosporine analogue produced by a blocked mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O- and N-methylation in the biosynthesis of staurosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism studies of indole derivatives using a staurosporine producer, Streptomyces staurosporeus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nitro analogue of staurosporine and other minor metabolites produced by a Streptomyces longisporoflavus strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16164546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2958.2005.04777.X

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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