(Q36429628)

14 August 2017

1 reference

title

The role of Wnt signaling in cancer and stem cells (English)

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14 August 2017

6

Rafael Rosell

1 reference

14 August 2017

Noemi Reguart

1

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14 August 2017

Biao He

2

1 reference

14 August 2017

Miquel Taron

3

1 reference

14 August 2017

Liang You

4

1 reference

14 August 2017

David M Jablons

5

1 reference

14 August 2017

language of work or name

English

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publication date

1 December 2005

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14 August 2017

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14 August 2017

volume

1

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14 August 2017

issue

6

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14 August 2017

page(s)

787-797

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The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Secreted antagonists of the Wnt signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt signaling and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The dishevelled protein is modified by wingless signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A frizzled homolog functions in a vertebrate Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT- beta-catenin-TCF signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

WNTs modulate cell fate and behavior during vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Biological properties and gene expression associated with metastatic potential of human osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Altered HOX and WNT7A expression in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Shutting down Wnt signal-activated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A new secreted protein that binds to Wnt proteins and inhibits their activities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

WIF1, a component of the Wnt pathway, is down‐regulated in prostate, breast, lung, and bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt signalling: antagonistic Dickkopfs

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The Wnt connection to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The APC gene in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Abnormalities of the APC/beta-catenin pathway in endometrial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt proteins promote neuronal differentiation in neural stem cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A role for Wnt signalling in self-renewal of haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Tissue repair and stem cell renewal in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Wnt2 as a new therapeutic target in malignant pleural mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

Functional genomic analysis of the Wnt-wingless signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.1.6.787

21 January 2018

Identifiers

DOI

10.2217/14796694.1.6.787

1 reference

14 August 2017

1 reference