(Q36430180)

14 August 2017

1 reference

title

Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice (English)

1 reference

14 August 2017

Johnson TM

1

1 reference

PubMed ID

16557272

14 August 2017

Attardi LD

series ordinal

2

1 reference

14 August 2017

1 June 2006

1 reference

Cell Death & Differentiation

14 August 2017

1 reference

14 August 2017

13

1 reference

14 August 2017

6

1 reference

14 August 2017

902-908

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401902

14 August 2017

0 references

cites work

The p53 story: layers of complexity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

p53 and disease: when the guardian angel fails

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Dissecting p53 tumor suppressor functions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Dissecting p53-dependent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Post-translational modification of p53 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Phosphorylation of serine 18 regulates distinct p53 functions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Mutation of mouse p53 Ser23 and the response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Temporal dissection of p53 function in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Modulation of mammalian life span by the short isoform of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

inferred from DOI database lookup

7 January 2021

based on heuristic

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

inferred from DOI database lookup

7 January 2021

based on heuristic

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401902

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4401902

1 reference

PubMed ID

16557272

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16557272