(Q36430189)

14 August 2017

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title

Pathogenetic mechanisms in thyroid follicular-cell neoplasia (English)

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14 August 2017

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Sylvia L Asa

3

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Shereen Ezzat

series ordinal

2

object named as

Shereen Ezzat

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14 August 2017

Tetsuo Kondo

1

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14 August 2017

language of work or name

English

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publication date

1 April 2006

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14 August 2017

published in

Nature Reviews Cancer

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14 August 2017

volume

6

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14 August 2017

issue

4

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14 August 2017

page(s)

292-306

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A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

14 August 2017

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Ret oncogene activation in papillary thyroid carcinoma: prevalence and implication on the histological parameters

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RET gene rearrangements (RET/PTC1 and RET/PTC3) in papillary thyroid carcinomas from an iodine-rich country (Japan).

21 January 2018

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Loss of p53 promotes anaplasia and local invasion in ret/PTC1-induced thyroid carcinomas

21 January 2018

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Heterogeneity in the distribution of RET/PTC rearrangements within individual post-Chernobyl papillary thyroid carcinomas

21 January 2018

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Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancer

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Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

21 January 2018

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Evidence that one subset of anaplastic thyroid carcinomas are derived from papillary carcinomas due to BRAF and p53 mutations

21 January 2018

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A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma

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21 January 2018

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BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

21 January 2018

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BRAF mutations typical of papillary thyroid carcinoma are more frequently detected in undifferentiated than in insular and insular-like poorly differentiated carcinomas

21 January 2018

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Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

21 January 2018

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Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.

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Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma

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On Trk for retrograde signaling

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Low frequency of rearrangements of the ret and trk proto-oncogenes in Japanese thyroid papillary carcinomas

21 January 2018

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NTRK1 re-arrangement in papillary thyroid carcinomas of children after the Chernobyl reactor accident

21 January 2018

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Targeting RAS signalling pathways in cancer therapy

21 January 2018

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Point mutations of ras oncogenes are an early event in thyroid tumorigenesis

21 January 2018

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Prevalence of activating ras mutations in morphologically characterized thyroid nodules.

21 January 2018

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N-ras mutation in poorly differentiated thyroid carcinomas: correlation with bone metastases and inverse correlation to thyroglobulin expression.

21 January 2018

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RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma.

21 January 2018

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Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations

21 January 2018

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Absence of RAS and p53 mutations in thyroid carcinomas of children after Chernobyl in contrast to adult thyroid tumours

21 January 2018

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Observer variation in the diagnosis of follicular variant of papillary thyroid carcinoma.

21 January 2018

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ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer.

21 January 2018

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PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]

21 January 2018

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The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition

21 January 2018

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Detection of the PAX8-PPAR gamma fusion oncogene in both follicular thyroid carcinomas and adenomas.

21 January 2018

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Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.

21 January 2018

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A subset of the follicular variant of papillary thyroid carcinoma harbors the PAX8-PPARgamma translocation.

21 January 2018

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Solitary, multiple, and familial oxyphil tumours of the thyroid gland

21 January 2018

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My approach to oncocytic tumours of the thyroid

21 January 2018

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Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours

21 January 2018

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Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors

21 January 2018

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mtDNA mutations increase tumorigenicity in prostate cancer

21 January 2018

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Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis

21 January 2018

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Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.

21 January 2018

1 reference

Fibroblast growth factor signaling in tumorigenesis

21 January 2018

1 reference

Basic fibroblast growth factor: an autocrine mitogen of rat thyroid follicular cells?

21 January 2018

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Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression

21 January 2018

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Fibroblast growth factor receptors as molecular targets in thyroid carcinoma.

21 January 2018

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Overexpression of fibroblast growth factor receptor 3 in a human thyroid carcinoma cell line results in overgrowth of the confluent cultures

21 January 2018

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Tyrosine kinase receptor indistinguishable from the c-met protein

21 January 2018

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Expression of the hepatocyte growth factor and c-met in normal thyroid, non-neoplastic, and neoplastic nodules

21 January 2018

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Met protein and hepatocyte growth factor (HGF) in papillary carcinoma of the thyroid: evidence for a pathogenetic role in tumourigenesis

21 January 2018

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Papillary carcinoma of the thyroid: evidence for a role for hepatocyte growth factor (HGF) in promoting tumour angiogenesis

21 January 2018

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MET receptor tyrosine kinase sequence alterations in differentiated thyroid carcinoma

21 January 2018

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Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

21 January 2018

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c‐Met expression in tall cell variant papillary carcinoma of the thyroid

21 January 2018

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The basic biology of HER2.

21 January 2018

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Expression of erbB receptors mRNA in thyroid tissues.

21 January 2018

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Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.

21 January 2018

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Epidermal growth factor (EGF)- and transforming growth factor alpha-stimulated invasion and growth of follicular thyroid cancer cells can be blocked by antagonism to the EGF receptor and tyrosine kinase in vitro

21 January 2018

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Epidermal growth factor stimulates cell proliferation and inhibits iodide uptake of FRTL-5 cells in vitro

21 January 2018

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Expression of angiogenesis stimulators and inhibitors in human thyroid tumors and correlation with clinical pathological features

21 January 2018

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Expression of vascular endothelial growth factor family messenger RNA in diseased thyroid tissues.

21 January 2018

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Expression of vascular endothelial growth factor-C in benign and malignant thyroid tumors

21 January 2018

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VEGF-D expression and lymph vessels play an important role for lymph node metastasis in papillary thyroid carcinoma

21 January 2018

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Intratumoral lymphatics and lymph node metastases in papillary thyroid carcinoma

21 January 2018

1 reference

Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1.

21 January 2018

1 reference

Apoptosis and proliferation in thyroid carcinoma: correlation with bcl-2 and p53 protein expression.

21 January 2018

1 reference

MIB-1 index in thyroid tumors: a predictor of the clinical course in papillary thyroid carcinoma.

21 January 2018

1 reference

Cyclin D1 and Cyclin E expression in malignant thyroid cells and in human thyroid carcinomas

21 January 2018

1 reference

Inverse association between cyclin D1 overexpression and retinoblastoma gene mutation in thyroid carcinomas

21 January 2018

1 reference

Evidence of gene deletion of p21 (WAF1/CIP1), a cyclin-dependent protein kinase inhibitor, in thyroid carcinomas

21 January 2018

1 reference

Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers

21 January 2018

1 reference

High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas

21 January 2018

1 reference

Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland

21 January 2018

1 reference

E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas.

21 January 2018

1 reference

N-cadherin-mediated adhesion and aberrant catenin expression in anaplastic thyroid-carcinoma cell lines.

21 January 2018

1 reference

Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis

21 January 2018

1 reference

Analysis of adenomatous polyposis coli gene in thyroid tumours

21 January 2018

1 reference

Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma

21 January 2018

1 reference

Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasm

21 January 2018

1 reference

Familial adenomatous polyposis-associated thyroid cancer: a clinical, pathological, and molecular genetics study

21 January 2018

1 reference

Gene expression in papillary thyroid carcinoma reveals highly consistent profiles

21 January 2018

1 reference

Absence of fibronectin and presence of plasminogen activator in both normal and malignant human mammary epithelial cells in culture

21 January 2018

1 reference

1alpha,25-Dihydroxyvitamin D3 targets PTEN-dependent fibronectin expression to restore thyroid cancer cell adhesiveness

21 January 2018

1 reference

A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression

21 January 2018

1 reference

Independent clonal origins of distinct tumor foci in multifocal papillary thyroid carcinoma.

21 January 2018

1 reference

Controversies in papillary microcarcinoma of the thyroid

21 January 2018

1 reference

Gene expression profiling identifies platelet-derived growth factor as a diagnostic molecular marker for papillary thyroid carcinoma

21 January 2018

1 reference

TIMP1 and SERPIN-A overexpression and TFF3 and CRABP1 underexpression as biomarkers for papillary thyroid carcinoma.

21 January 2018

1 reference

Malignant transformation of thyroid follicular cells by galectin-3.

21 January 2018

1 reference

Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes

21 January 2018

1 reference

BRAF mutation predicts sensitivity to MEK inhibition

21 January 2018

1 reference

Wnt/beta-catenin signaling mediates antineoplastic effects of imatinib mesylate (gleevec) in anaplastic thyroid cancer

21 January 2018

1 reference

Thyroid gland clonality revisited: the embryonal patch size of the normal human thyroid gland is very large, suggesting X-chromosome inactivation tumor clonality studies of thyroid tumors have to be interpreted with caution

21 January 2018

1 reference

The association of well-differentiated thyroid carcinoma with insular or anaplastic thyroid carcinoma; evidence for dedifferentiation in tumor progression

21 January 2018

1 reference

Oncogene profile of papillary thyroid carcinoma

21 January 2018

1 reference

Cytoplasmic staining of erbB-2 but not mRNA levels correlates with differentiation in human thyroid neoplasia

21 January 2018

1 reference

Immunohistochemical Diagnosis of Papillary Thyroid Carcinoma

21 January 2018

1 reference

Clonality of thyroid nodules in sporadic goiter

21 January 2018

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Cyclin D1 protein expression predicts metastatic behavior in thyroid papillary microcarcinomas but is not associated with gene amplification

21 January 2018

1 reference

Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas

21 January 2018

1 reference

Thyroid cancer after Chernobyl

21 January 2018

1 reference

Poorly differentiated ("insular") thyroid carcinoma. A reinterpretation of Langhans' "wuchernde Struma"

21 January 2018

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Thyroid cancer and thyroiditis in Salta, Argentina: a 40-yr study in relation to iodine prophylaxis

31 March 2020

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Familial papillary thyroid microcarcinoma: a new clinical entity

31 March 2020

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The diagnostic value of flow cytometric DNA measurements in selected disorders of the human thyroid

31 March 2020

1 reference

Cytogenetic investigations of 340 thyroid hyperplasias and adenomas revealing correlations between cytogenetic findings and histology

31 March 2020

1 reference

Adenomas and follicular carcinomas of the thyroid display two major patterns of chromosomal changes

31 March 2020

1 reference

Benign and malignant thyroid lesions show instability at microsatellite loci

31 March 2020

1 reference

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway

31 March 2020

1 reference

Prognostic significance of RET and NTRK1 rearrangements in sporadic papillary thyroid carcinoma

31 March 2020

1 reference

Distinct frequency of ret rearrangements in papillary thyroid carcinomas of children and adults from Belarus

31 March 2020

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Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

31 March 2020

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Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas

31 March 2020

1 reference

Frequent RET rearrangements in thyroid papillary microcarcinoma detected by interphase fluorescence in situ hybridization

31 March 2020

1 reference

Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis

31 March 2020

1 reference

ret/PTC-1 Activation in Hashimoto Thyroiditis

31 March 2020

1 reference

Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas

31 March 2020

1 reference

Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

31 March 2020

1 reference

Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma

31 March 2020

1 reference

BRAFMutations Are Not a Major Event in Post-Chernobyl Childhood Thyroid Carcinomas

31 March 2020

1 reference

Prevalence of Ras mutations in thyroid neoplasia

31 March 2020

1 reference

Observer variation of encapsulated follicular lesions of the thyroid gland

31 March 2020

1 reference

PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses

31 March 2020

1 reference

The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions

31 March 2020

1 reference

Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid

31 March 2020

1 reference

Pituitary tumor transforming gene and fibroblast growth factor-2 expression: potential prognostic indicators in differentiated thyroid cancer

31 March 2020

1 reference

Expression of Met protein in thyroid tumours

31 March 2020

1 reference

Oncoproteins and tumor progression in papillary thyroid carcinoma: presence of epidermal growth factor receptor, c-erbB-2 protein, estrogen receptor related protein, p21-ras protein, and proliferation indicators in relation to tumor recurrences and

31 March 2020

1 reference

Vascular endothelial growth factor gene and protein: strong expression in thyroiditis and thyroid carcinoma

31 March 2020

1 reference

Expression of vascular endothelial growth factor (VEGF) in human thyroid neoplasms

31 March 2020

1 reference

Apoptosis and proliferative activity in thyroid tumors

31 March 2020

1 reference

E2F-1 transcription factor is overexpressed in oxyphilic thyroid tumors

31 March 2020

1 reference

Cyclin D1 overexpression in thyroid carcinomas: relation with clinico-pathological parameters, retinoblastoma gene product, and Ki67 labeling index

31 March 2020

1 reference

Immunohistochemical expression of cyclin D1, E2F-1, and Ki-67 in benign and malignant thyroid lesions

31 March 2020

1 reference

Cyclin E expression in papillary thyroid carcinoma: relation to staging

31 March 2020

1 reference

The role of cell cycle regulatory protein, cyclin D1, in the progression of thyroid cancer

31 March 2020

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p27kip1 expression distinguishes papillary hyperplasia in Graves' disease from papillary thyroid carcinoma

31 March 2020

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Lack of p16/CDKN2 alterations in thyroid carcinomas

31 March 2020

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Infrequent CDKN2 mutation in human differentiated thyroid cancers

31 March 2020

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Retinoblastoma expression in thyroid neoplasms

31 March 2020

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p53 gene mutation in thyroid carcinoma

31 March 2020

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Mutations of p53 in thyroid carcinoma with an insular component

31 March 2020

1 reference

Immunohistochemical Localization of p53 in Human Thyroid Neoplasms: Correlation with Biological Behavior

31 March 2020

1 reference

E-cadherin expression in follicular carcinoma of the thyroid

31 March 2020

1 reference

E-cadherin gene alterations are rare events in thyroid tumors

31 March 2020

1 reference

Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant

31 March 2020

1 reference

Beta- and gamma-catenin expression in thyroid carcinomas

31 March 2020

1 reference

Absence of mutations in the beta-catenin and adenomatous polyposis coli genes in papillary and follicular thyroid carcinomas

31 March 2020

1 reference

Strong intracellular and negative peripheral expression of fibronectin in tumor cells contribute to invasion and metastasis in papillary thyroid carcinoma

31 March 2020

1 reference

Analysis of ret/PTC gene rearrangements refines the fine needle aspiration diagnosis of thyroid cancer

31 March 2020

1 reference

Multiple thyroid involvement (intraglandular metastasis) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients

31 March 2020

1 reference

Clonal origin of non-medullary thyroid tumours assessed by non-random X-chromosome inactivation

31 March 2020

1 reference

Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications

31 March 2020

1 reference

Characterization of thyroid 'follicular neoplasms' in fine-needle aspiration cytological specimens using a panel of immunohistochemical markers: a proposal for clinical application

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1836

1 reference

14 August 2017

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