(Q36437505)

14 August 2017

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title

What makes a good anti-inflammatory drug target? (English)

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14 August 2017

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David L Simmons

1

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14 August 2017

publication date

1 March 2006

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14 August 2017

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14 August 2017

volume

11

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14 August 2017

issue

5-6

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14 August 2017

page(s)

210-219

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The role of innovation in drug development

14 August 2017

cites work

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Tumor necrosis, cachexia, shock, and inflammation: a common mediator

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Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

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Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

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Molecular phylogeny within type I cytokines and their cognate receptors

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The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions

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Interferons, interferon-like cytokines, and their receptors

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The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

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A sequence-based map of the nine genes of the human interleukin-1 cluster

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New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

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Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab

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Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

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The B7 family revisited

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The identification of ligands at orphan G-protein coupled receptors

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Characterization of the human cysteinyl leukotriene CysLT1 receptor

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Principles for modulation of the nuclear receptor superfamily

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Aspirin and steroids: new mechanistic findings and avenues for drug discovery

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7 January 2021

Inflammatory resolution: new opportunities for drug discovery

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The structure of interleukin-2 complexed with its alpha receptor

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7 January 2021

Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines

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Identifiers

DOI

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14 August 2017

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