(Q36444557)

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Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction

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Europe PubMed Central

PMC publication ID

14 August 2017

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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Parkinson's disease

1 reference

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7

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Sheng-Di Chen

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Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Jing Pan

1

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Europe PubMed Central

PMC publication ID

14 August 2017

Hui Li

2

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Europe PubMed Central

PMC publication ID

14 August 2017

Jian-Fang Ma

3

1 reference

Europe PubMed Central

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14 August 2017

Yu-Yan Tan

4

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Europe PubMed Central

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14 August 2017

Qin Xiao

5

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Europe PubMed Central

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14 August 2017

Jian-Qing Ding

6

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Europe PubMed Central

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14 August 2017

publication date

20 August 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Translational Neurodegeneration

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Europe PubMed Central

PMC publication ID

14 August 2017

1

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Europe PubMed Central

PMC publication ID

14 August 2017

1

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Europe PubMed Central

PMC publication ID

14 August 2017

16

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Europe PubMed Central

PMC publication ID

14 August 2017

MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Phase II trial of curcumin in patients with advanced pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Parkinson's disease: clinical features and diagnosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Expression of FasL and its interaction with Fas are mediated by c-Jun N-terminal kinase (JNK) pathway in 6-OHDA-induced rat model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

NMDA inhibitors cause apoptosis of pyramidal neurons in mature piriform cortex: evidence for a nitric oxide-mediated effect involving inhibitory interneurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

The neuroprotective effects of K252a through inhibiting MLK3/MKK7/JNK3 signaling pathway on ischemic brain injury in rat hippocampal CA1 region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

A critical role of neural-specific JNK3 for ischemic apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

JNK phosphorylates paxillin and regulates cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

30 September 2017

Involvement of oxidative stress in the rapid Akt1 regulating a JNK scaffold during ischemia in rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

28 June 2018

2-Methoxyestradiol-induced phosphorylation of Bcl-2: uncoupling from JNK/SAPK activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

28 June 2018

Changes in diagnosis with follow-up in an incident cohort of patients with parkinsonism.

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Pathological description of a non-motor variant of multiple system atrophy.

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Levodopa induces apoptosis in cultured neuronal cells--a possible accelerator of nigrostriatal degeneration in Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits.

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Neuroprotection of Tat-GluR6-9c against neuronal death induced by kainate in rat hippocampus via nuclear and non-nuclear pathways

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Inhibition of radiation induced nitration by curcumin and nicotinamide in mouse macrophages

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

Neuroprotection against ischaemic brain injury by a GluR6-9c peptide containing the TAT protein transduction sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

21 September 2018

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514118

21 September 2018

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

1 reference

https://api.crossref.org/works/10.1186%2F2047-9158-1-16

21 January 2018

K252a prevents nigral dopaminergic cell death induced by 6-hydroxydopamine through inhibition of both mixed-lineage kinase 3/c-Jun NH2-terminal kinase 3 (JNK3) and apoptosis-inducing kinase 1/JNK3 signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23210631

12 December 2020

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10.1186/2047-9158-1-16

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Europe PubMed Central

PMC publication ID

14 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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