(Q36450196)

14 August 2017

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells (English)

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14 August 2017

1 reference

12

Tõnu Esko

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Leif S Ludwig

Leif S Ludwig

4

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Claudia Fiorini

Claudia Fiorini

2

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Mitchell J Weiss

Mitchell J Weiss

16

0 references

Jacob C Ulirsch

Jacob C Ulirsch

8

0 references

Joel Hirschhorn

15

Joel N Hirschhorn

1 reference

14 August 2017

Felix C Giani

1

1 reference

14 August 2017

Aoi Wakabayashi

3

1 reference

14 August 2017

Rany M Salem

5

1 reference

14 August 2017

Chintan D Jobaliya

6

1 reference

14 August 2017

Stephanie N Regan

7

1 reference

14 August 2017

Ge Liang

9

1 reference

14 August 2017

Orna Steinberg-Shemer

10

1 reference

14 August 2017

Michael H Guo

11

1 reference

14 August 2017

Wei Tong

13

1 reference

14 August 2017

Carlo Brugnara

14

1 reference

14 August 2017

Leonard I Zon

17

1 reference

14 August 2017

Stella T Chou

18

1 reference

14 August 2017

Deborah L French

19

1 reference

14 August 2017

Kiran Musunuru

20

1 reference

14 August 2017

Vijay G Sankaran

21

1 reference

14 August 2017

language of work or name

English

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publication date

20 October 2015

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14 August 2017

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14 August 2017

18

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14 August 2017

1

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14 August 2017

73-78

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PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Tuning cytokine receptor signaling by re-orienting dimer geometry with surrogate ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Hematopoietic differentiation of pluripotent stem cells in culture.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Altered translation of GATA1 in Diamond-Blackfan anemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Large-scale production of red blood cells from stem cells: what are the technical challenges ahead?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Hematopoietic specification from human pluripotent stem cells: current advances and challenges toward de novo generation of hematopoietic stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Challenges in the management of the blood supply

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

A TALEN genome-editing system for generating human stem cell-based disease models

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Seventy-five genetic loci influencing the human red blood cell

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

The switch from fetal to adult hemoglobin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Role of the adaptor protein LNK in normal and malignant hematopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

The potential of stem cells as an in vitro source of red blood cells for transfusion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

A nonsynonymous LNK polymorphism associated with idiopathic erythrocytosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Proof of principle for transfusion of in vitro-generated red blood cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

30 September 2017

Hereditary spherocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Diamond-blackfan anemia: in vitro response of erythroid progenitors to the ligand for c-kit

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

LNK mutations in JAK2 mutation-negative erythrocytosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707983

Simultaneous measurement of reticulocyte and red blood cell indices in healthy subjects and patients with microcytic and macrocytic anemia

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26607381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Defining the path to hematopoietic stem cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26607381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEM.2015.09.015

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26607381

1 reference